D010042Chemicals & DrugsD04.210.500.155.580.130.750.600D09.408.180.810.60018240.98415Ouabainplugins:FeaturedVideosFeatured Videosplugins:TwitterTwitterprns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonBiochemistry and Molecular Biology0.6245910.0052260418research area of0.5687090.0054957824subject area forGokhan M.Mutlu0G98H611OfnamXNnYUHhvWD+6g==Gokhan M. Mutlu0.000000000000000.000000000000002890Mutlu, Gokhan M.ProfessorMedicine-Pulmonary and Critical CareObstetrics and Gynecology-Maternal Fetal Medicine21911500Sandtner W, Egwolf B, Khalili-Araghi F, Sánchez-Rodríguez JE, Roux B, Bezanilla F, Holmgren MThe Journal of biological chemistryOuabain binding site in a functioning Na+/K+ ATPase. J Biol Chem. 2011 Nov 04; 286(44):38177-38183.J Biol Chem2011-09-12T00:00:002011Ouabain binding site in a functioning Na+/K+ ATPase.SaroshRanaSarosh Rana0.000000000000000.000000000000003121Rana, SaroshProfessorhttp://nerve.bsd.uchicago.eduExcitability, Molecular Basishttps://mutlulab.uchicago.edu/Mutlu Labhttp://obg.bsd.uchicago.edu/FacultyResearch/Ranalab/index.htmlRana Preeclampsia labhttp://nerve.bsd.uchicago.edu/FBLab Site@saroshranaOBBiochem/Mol BioMedicineUniversity of ChicagoNickolaiDulin2WZ8B6gbOfnamXNnYUHhvWD+6g==Nickolai Dulin41.78927490000000-87.601250000000001611Dulin, NickolaiAssociate ProfessorFatemehKhalili-AraghiFatemeh Khalili-Araghi41.78927490000000-87.60125000000000888Khalili-Araghi, FatemehPostdoctoral ScholarFranciscoBezanillaFrancisco Bezanilla41.78927490000000-87.60125000000000987Bezanilla, FranciscoProfessortrue1Postdoctoral ScholarPostdoctoral Scholartrue1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessor25637661Sánchez-Rodríguez JE, Khalili-Araghi F, Miranda P, Roux B, Holmgren M, Bezanilla FJournal of molecular biologyA structural rearrangement of the Na+/K+-ATPase traps ouabain within the external ion permeation pathway. J Mol Biol. 2015 Mar 27; 427(6 Pt B):1335-1344.J Mol Biol2015-01-28T00:00:002015A structural rearrangement of the Na+/K+-ATPase traps ouabain within the external ion permeation pathway.26067145Akimova OA, Tverskoi AM, Smolyaninova LV, Mongin AA, Lopina OD, La J, Dulin NO, Orlov SNApoptosis : an international journal on programmed cell deathCritical role of the a1-Na(+), K(+)-ATPase subunit in insensitivity of rodent cells to cytotoxic action of ouabain. Apoptosis. 2015 Sep; 20(9):1200-10.Apoptosis2015-09-01T00:00:002015Critical role of the a1-Na(+), K(+)-ATPase subunit in insensitivity of rodent cells to cytotoxic action of ouabain.24970393Rana S, Rajakumar A, Geahchan C, Salahuddin S, Cerdeira AS, Burke SD, George EM, Granger JP, Karumanchi SAFASEB journal : official publication of the Federation of American Societies for Experimental BiologyOuabain inhibits placental sFlt1 production by repressing HSP27-dependent HIF-1a pathway. FASEB J. 2014 Oct; 28(10):4324-34.FASEB J2014-06-26T00:00:002014Ouabain inhibits placental sFlt1 production by repressing HSP27-dependent HIF-1a pathway.26851261La J, Reed EB, Koltsova S, Akimova O, Hamanaka RB, Mutlu GM, Orlov SN, Dulin NOAmerican journal of physiology. Lung cellular and molecular physiologyRegulation of myofibroblast differentiation by cardiac glycosides. Am J Physiol Lung Cell Mol Physiol. 2016 05 01; 310(9):L815-23.Am J Physiol Lung Cell Mol Physiol2016-02-05T00:00:002016Regulation of myofibroblast differentiation by cardiac glycosides.