Mutant Calreticulin Requires Both Its Mutant C-terminus and the Thrombopoietin Receptor for Oncogenic Transformation.

Mutant Calreticulin Requires Both Its Mutant C-terminus and the Thrombopoietin Receptor for Oncogenic Transformation. Cancer Discov. 2016 Apr; 6(4):368-81.

View in: PubMed

subject areas

Animals
Base Sequence
Bone Marrow Transplantation
Calreticulin
Cell Line
Cell Transformation, Neoplastic
Disease Models, Animal
Female
Frameshift Mutation
Hematopoietic Stem Cells
Humans
Janus Kinases
Mice
Mutation
Myeloproliferative Disorders
Phenotype
Protein Binding
Protein Interaction Domains and Motifs
Protein Kinase Inhibitors
Receptors, Thrombopoietin
Signal Transduction
STAT Transcription Factors
Structure Collapse