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Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth.
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Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth.
Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth. Sci Signal. 2009 Nov 17; 2(97):ra73.
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PubMed
subject areas
Adenosine Triphosphate
Animals
Cell Line
Cell Line, Tumor
Cell Proliferation
Fructosediphosphates
Glucose
Glycolysis
Humans
Immunoblotting
K562 Cells
Male
Mice
Mice, Nude
Mutation
Neoplasms
Neoplasms, Experimental
Oxygen Consumption
Phosphorylation
Proteomics
Pyruvate Kinase
Receptor, Fibroblast Growth Factor, Type 1
Transplantation, Heterologous
Tumor Burden
Tyrosine
authors with profiles
Jing Chen