D006903Chemicals & DrugsD08.811.682.047.820.150.4156160.993388Hydroxymethylglutaryl CoA Reductasesprns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonOrganismal Biology and Anatomy0.4543960.01753946research area of0.2228830.017599319subject area for30929013Kar SP, Brenner H, Giles GG, Huo D, Milne RL, Rennert G, Simard J, Zheng W, Burgess S, Pharoah PDPInternational journal of epidemiologyBody mass index and the association between low-density lipoprotein cholesterol as predicted by HMGCR genetic variants and breast cancer risk. Int J Epidemiol. 2019 10 01; 48(5):1727-1730.Int J Epidemiol2019-10-01T00:00:002019Body mass index and the association between low-density lipoprotein cholesterol as predicted by HMGCR genetic variants and breast cancer risk.11833826Davidson MH, Lukacsko P, Sun JX, Phillips G, Walters E, Sterman A, Niecestro R, Friedhoff LClinical therapeuticsA multiple-dose pharmacodynamic, safety, and pharmacokinetic comparison of extended- and immediate-release formulations of lovastatin. Clin Ther. 2002 Jan; 24(1):112-25.Clin Ther2002-01-01T00:00:002002A multiple-dose pharmacodynamic, safety, and pharmacokinetic comparison of extended- and immediate-release formulations of lovastatin.11584328Davidson MHJournal of cardiovascular pharmacology and therapeuticsTreatment of the elderly with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors: focus on drug interactions. J Cardiovasc Pharmacol Ther. 2001 Jul; 6(3):219-29.J Cardiovasc Pharmacol Ther2001-07-01T00:00:002001Treatment of the elderly with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors: focus on drug interactions.Public Health Scienceshttps://voices.uchicago.edu/princelab/Prince Lab Websitehttp://bcrisktool.uchicago.edu/Breast Cancer Risk Calculator for Africanshttps://biosciences.uchicago.edu/UChicago Bioscienceshttp://abcs.uchicago.eduABCS databaseBiochem/Mol BioMedicineUniversity of ChicagoDezhengHuo02p8BIEdHO3VhXIqYlXqvXD598K+6LJRPnx+Yw==Dezheng Huo41.78927490000000-87.60125000000000130Huo, DezhengProfessorVictoria E.PrincewXJ7Aq8WHMzMknJtY0fp/Cv/+94=Victoria E. Prince41.78927490000000-87.601250000000001396Prince, Victoria E.ProfessorTheodoreSteckTheodore L. Steck41.78927490000000-87.601250000000002431Steck, TheodoreEmeritus/EmeritaJamesLiaoJames Liao41.78927490000000-87.60125000000000382Liao, JamesProfessorMichael H.DavidsonMichael H. Davidson41.78927490000000-87.60125000000000611Davidson, Michael H.Clinical Professortrue1Emeritus/EmeritaEmeritus/Emeritatrue1ProfessorProfessortrue1Clinical ProfessorClinical Professortrue1ProfessorProfessortrue1ProfessorProfessor12163444Liao JKThe Journal of clinical investigationIsoprenoids as mediators of the biological effects of statins. J Clin Invest. 2002 Aug; 110(3):285-8.J Clin Invest2002-08-01T00:00:002002Isoprenoids as mediators of the biological effects of statins.9395516Laufs U, Fata VL, Liao JKThe Journal of biological chemistryInhibition of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase blocks hypoxia-mediated down-regulation of endothelial nitric oxide synthase. J Biol Chem. 1997 Dec 12; 272(50):31725-9.J Biol Chem1997-12-12T00:00:001997Inhibition of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase blocks hypoxia-mediated down-regulation of endothelial nitric oxide synthase.Medicine-Cardiology