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m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade.
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m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade.
m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade. Nat Commun. 2019 06 25; 10(1):2782.
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PubMed
subject areas
Adenosine
Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Animals
Antibodies, Monoclonal
Antibodies, Monoclonal, Humanized
Carcinogenesis
Cell Line, Tumor
Cell Proliferation
Demethylation
DNA Methylation
Female
Humans
Immunotherapy
Melanoma
Mice
Mice, Inbred C57BL
Mice, Nude
Programmed Cell Death 1 Receptor
RNA Stability
RNA, Messenger
authors with profiles
Chuan He
Yu-Ying He