Raghu Mirmira to Humans
This is a "connection" page, showing publications Raghu Mirmira has written about Humans.
Connection Strength
0.599
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Preclinical evaluation of tyrosine kinase 2 inhibitors for human beta-cell protection in type 1 diabetes. Diabetes Obes Metab. 2020 10; 22(10):1827-1836.
Score: 0.024
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Hypusinated eIF5A is expressed in the pancreas and spleen of individuals with type 1 and type 2 diabetes. PLoS One. 2020; 15(3):e0230627.
Score: 0.023
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Distinct gene expression pathways in islets from individuals with short- and long-duration type 1 diabetes. Diabetes Obes Metab. 2018 08; 20(8):1859-1867.
Score: 0.020
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Inhibition of 12/15-Lipoxygenase Protects Against ß-Cell Oxidative Stress and Glycemic Deterioration in Mouse Models of Type 1 Diabetes. Diabetes. 2017 11; 66(11):2875-2887.
Score: 0.019
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Molecular mechanisms of nonalcoholic fatty liver disease: Potential role for 12-lipoxygenase. J Diabetes Complications. 2017 Nov; 31(11):1630-1637.
Score: 0.019
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Measurement of Differentially Methylated INS DNA Species in Human Serum Samples as a Biomarker of Islet ß Cell Death. J Vis Exp. 2016 12 21; (118).
Score: 0.019
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Biomarkers of ß-Cell Stress and Death in Type 1 Diabetes. Curr Diab Rep. 2016 10; 16(10):95.
Score: 0.018
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Editorial: Lessons From the Classic Scientific Literature. Mol Endocrinol. 2015 Oct; 29(10):1385-7.
Score: 0.017
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Elevations in Circulating Methylated and Unmethylated Preproinsulin DNA in New-Onset Type 1 Diabetes. Diabetes. 2015 Nov; 64(11):3867-72.
Score: 0.017
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Minireview: 12-Lipoxygenase and Islet ß-Cell Dysfunction in Diabetes. Mol Endocrinol. 2015 Jun; 29(6):791-800.
Score: 0.016
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Editorial: The vulnerable physician-scientist. Mol Endocrinol. 2014 May; 28(5):603-6.
Score: 0.015
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From immunobiology to ß-cell biology: the changing perspective on type 1 diabetes. Islets. 2014; 6(2):e28778.
Score: 0.015
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Lost in translation: endoplasmic reticulum stress and the decline of ß-cell health in diabetes mellitus. Diabetes Obes Metab. 2013 Sep; 15 Suppl 3:159-69.
Score: 0.015
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Translational control of inducible nitric oxide synthase by p38 MAPK in islet ß-cells. Mol Endocrinol. 2013 Feb; 27(2):336-49.
Score: 0.014
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Hypusine: a new target for therapeutic intervention in diabetic inflammation. Discov Med. 2010 Jul; 10(50):18-23.
Score: 0.012
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Inducible pluripotent stem cells: not quite ready for prime time? Curr Opin Organ Transplant. 2010 Feb; 15(1):61-7.
Score: 0.012
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Stem cells and the future of organ transplantation. Curr Opin Organ Transplant. 2010 Feb; 15(1):52-3.
Score: 0.012
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Development of insulin-producing cells from primitive biologic precursors. Curr Opin Organ Transplant. 2009 Feb; 14(1):56-63.
Score: 0.011
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A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis. Mol Genet Metab. 2007 Sep-Oct; 92(1-2):43-55.
Score: 0.010
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Glucose regulation of insulin gene transcription and pre-mRNA processing in human islets. Diabetes. 2007 Mar; 56(3):827-35.
Score: 0.009
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Pdx-1 links histone H3-Lys-4 methylation to RNA polymerase II elongation during activation of insulin transcription. J Biol Chem. 2005 Oct 28; 280(43):36244-53.
Score: 0.008
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The C-terminal domain of the beta cell homeodomain factor Nkx6.1 enhances sequence-selective DNA binding at the insulin promoter. Biochemistry. 2005 Aug 23; 44(33):11269-78.
Score: 0.008
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The transcriptional repressor Nkx6.1 also functions as a deoxyribonucleic acid context-dependent transcriptional activator during pancreatic beta-cell differentiation: evidence for feedback activation of the nkx6.1 gene by Nkx6.1. Mol Endocrinol. 2004 Jun; 18(6):1363-75.
Score: 0.008
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Transcription factors direct the development and function of pancreatic beta cells. Trends Endocrinol Metab. 2003 Mar; 14(2):78-84.
Score: 0.007
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The demise of islet allotransplantation in the United States: A call for an urgent regulatory update. Am J Transplant. 2021 04; 21(4):1365-1375.
Score: 0.006
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Hypusination Orchestrates the Antimicrobial Response of Macrophages. Cell Rep. 2020 12 15; 33(11):108510.
Score: 0.006
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The role of beta-cell dysfunction in early type 1 diabetes. Curr Opin Endocrinol Diabetes Obes. 2020 08; 27(4):215-224.
Score: 0.006
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Circulating unmethylated CHTOP and INS DNA fragments provide evidence of possible islet cell death in youth with obesity and diabetes. Clin Epigenetics. 2020 07 31; 12(1):116.
Score: 0.006
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Our Response to COVID-19 as Endocrinologists and Diabetologists. J Clin Endocrinol Metab. 2020 05 01; 105(5).
Score: 0.006
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Nanomedicine-Based Strategies for Diabetes: Diagnostics, Monitoring, and Treatment. Trends Endocrinol Metab. 2020 06; 31(6):448-458.
Score: 0.006
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Circulating Unmethylated Insulin DNA As a Biomarker of Human Beta Cell Death: A Multi-laboratory Assay Comparison. J Clin Endocrinol Metab. 2020 03 01; 105(3).
Score: 0.006
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Nuclear Translocation of Glutaminase GLS2 in Human Cancer Cells Associates with Proliferation Arrest and Differentiation. Sci Rep. 2020 02 10; 10(1):2259.
Score: 0.006
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Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention. Cell Metab. 2020 02 04; 31(2):363-374.e6.
Score: 0.006
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Hypusine biosynthesis in ß cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis. Sci Signal. 2019 12 03; 12(610).
Score: 0.006
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Profiling of RNAs from Human Islet-Derived Exosomes in a Model of Type 1 Diabetes. Int J Mol Sci. 2019 11 25; 20(23).
Score: 0.006
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Abnormalities in proinsulin processing in islets from individuals with longstanding T1D. Transl Res. 2019 11; 213:90-99.
Score: 0.006
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The role of proteomics in assessing beta-cell dysfunction and death in type 1 diabetes. Expert Rev Proteomics. 2019 07; 16(7):569-582.
Score: 0.006
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A Versatile, Portable Intravital Microscopy Platform for Studying Beta-cell Biology In Vivo. Sci Rep. 2019 06 11; 9(1):8449.
Score: 0.006
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Response to Comment on Sims et al. Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes. Diabetes Care 2019;42:258-264. Diabetes Care. 2019 05; 42(5):e85-e86.
Score: 0.005
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eIF5A inhibition influences T cell dynamics in the pancreatic microenvironment of the humanized mouse model of Type 1 Diabetes. Sci Rep. 2019 02 07; 9(1):1533.
Score: 0.005
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Combined Analysis of GAD65, miR-375, and Unmethylated Insulin DNA Following Islet Transplantation in Patients With T1D. J Clin Endocrinol Metab. 2019 02 01; 104(2):451-460.
Score: 0.005
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Recessive Rare Variants in Deoxyhypusine Synthase, an Enzyme Involved in the Synthesis of Hypusine, Are Associated with a Neurodevelopmental Disorder. Am J Hum Genet. 2019 02 07; 104(2):287-298.
Score: 0.005
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Analysis of serum Hsp90 as a potential biomarker of ß cell autoimmunity in type 1 diabetes. PLoS One. 2019; 14(1):e0208456.
Score: 0.005
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Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes. Diabetes Care. 2019 02; 42(2):258-264.
Score: 0.005
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Cellular metabolism constrains innate immune responses in early human ontogeny. Nat Commun. 2018 11 16; 9(1):4822.
Score: 0.005
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Role of the 12-lipoxygenase pathway in diabetes pathogenesis and complications. Pharmacol Ther. 2019 03; 195:100-110.
Score: 0.005
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Persistent elevations in circulating INS DNA among subjects with longstanding type 1 diabetes. Diabetes Obes Metab. 2019 01; 21(1):95-102.
Score: 0.005
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Biomarkers of islet beta cell stress and death in type 1 diabetes. Diabetologia. 2018 11; 61(11):2259-2265.
Score: 0.005
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1,25-Dihydroxyvitamin D3 enhances glucose-stimulated insulin secretion in mouse and human islets: a role for transcriptional regulation of voltage-gated calcium channels by the vitamin D receptor. J Steroid Biochem Mol Biol. 2019 01; 185:17-26.
Score: 0.005
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Immune reconstitution in ART treated, but not untreated HIV infection, is associated with abnormal beta cell function. PLoS One. 2018; 13(5):e0197080.
Score: 0.005
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Interleukin-6 Reduces ß-Cell Oxidative Stress by Linking Autophagy With the Antioxidant Response. Diabetes. 2018 08; 67(8):1576-1588.
Score: 0.005
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IFN-a induces a preferential long-lasting expression of MHC class I in human pancreatic beta cells. Diabetologia. 2018 03; 61(3):636-640.
Score: 0.005
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Elevated unmethylated and methylated insulin DNA are unique markers of A+ß+ ketosis prone diabetes. J Diabetes Complications. 2018 02; 32(2):193-195.
Score: 0.005
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A system for detecting high impact-low frequency mutations in primary tumors and metastases. Oncogene. 2018 01 11; 37(2):185-196.
Score: 0.005
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Comparative quantitative proteomic analysis of disease stratified laser captured microdissected human islets identifies proteins and pathways potentially related to type 1 diabetes. PLoS One. 2017; 12(9):e0183908.
Score: 0.005
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12-Lipoxygenase Inhibitor Improves Functions of Cytokine-Treated Human Islets and Type 2 Diabetic Islets. J Clin Endocrinol Metab. 2017 08 01; 102(8):2789-2797.
Score: 0.005
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Loss of mTORC1 signalling impairs ß-cell homeostasis and insulin processing. Nat Commun. 2017 07 12; 8:16014.
Score: 0.005
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Elevations in the Fasting Serum Proinsulin-to-C-Peptide Ratio Precede the Onset of Type 1 Diabetes. Diabetes Care. 2016 Sep; 39(9):1519-26.
Score: 0.004
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Loss of Free Fatty Acid Receptor 2 leads to impaired islet mass and beta cell survival. Sci Rep. 2016 06 21; 6:28159.
Score: 0.004
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Proinsulin and heat shock protein 90 as biomarkers of beta-cell stress in the early period after onset of type 1 diabetes. Transl Res. 2016 Feb; 168:96-106.e1.
Score: 0.004
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An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion. Mol Endocrinol. 2015 Jul; 29(7):1055-66.
Score: 0.004
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Transcriptional activity of the islet ß cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9. J Biol Chem. 2015 Apr 10; 290(15):9812-22.
Score: 0.004
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Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic ß cells. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):E2319-28.
Score: 0.004
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Syntaxin 4 up-regulation increases efficiency of insulin release in pancreatic islets from humans with and without type 2 diabetes mellitus. J Clin Endocrinol Metab. 2014 May; 99(5):E866-70.
Score: 0.004
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Eukaryotic translation initiation factor 5A inhibition alters physiopathology and immune responses in a "humanized" transgenic mouse model of type 1 diabetes. Am J Physiol Endocrinol Metab. 2014 Apr 01; 306(7):E791-8.
Score: 0.004
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Mouse and human islets survive and function after coating by biosilicification. Am J Physiol Endocrinol Metab. 2013 Nov 15; 305(10):E1230-40.
Score: 0.004
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Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-Alox15(null) mice, leading to protection against type 1 diabetes development. PLoS One. 2013; 8(2):e56763.
Score: 0.004
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Insights into mentorship for endocrinologists. J Clin Endocrinol Metab. 2012 Nov; 97(11):3891-6.
Score: 0.003
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Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain. Mol Cell Biol. 2010 Sep; 30(17):4234-44.
Score: 0.003
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AGI-1067, a novel antioxidant and anti-inflammatory agent, enhances insulin release and protects mouse islets. Mol Cell Endocrinol. 2010 Jul 29; 323(2):246-55.
Score: 0.003
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Liver X receptor agonists augment human islet function through activation of anaplerotic pathways and glycerolipid/free fatty acid cycling. J Biol Chem. 2010 Feb 19; 285(8):5392-404.
Score: 0.003
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Regenerative medicine and tissue engineering: contribution of stem cells in organ transplantation. Curr Opin Organ Transplant. 2009 Feb; 14(1):46-50.
Score: 0.003
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Differential expression of cell cycle proteins during ageing of pancreatic islet cells. Diabetes Obes Metab. 2008 Nov; 10 Suppl 4:136-46.
Score: 0.003
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Research resource: nuclear hormone receptor expression in the endocrine pancreas. Mol Endocrinol. 2008 Oct; 22(10):2353-63.
Score: 0.003
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Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1. Mol Cell Biol. 2008 May; 28(10):3465-76.
Score: 0.003
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Trefoil factor 3 stimulates human and rodent pancreatic islet beta-cell replication with retention of function. Mol Endocrinol. 2008 May; 22(5):1251-9.
Score: 0.003
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Proendocrine genes coordinate the pancreatic islet differentiation program in vitro. Proc Natl Acad Sci U S A. 2004 Sep 07; 101(36):13245-50.
Score: 0.002
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Regulation of the pancreatic pro-endocrine gene neurogenin3. Diabetes. 2001 May; 50(5):928-36.
Score: 0.002
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Interactions of a hybrid insulin/insulin-like growth factor-I analog with chimeric insulin/type I insulin-like growth factor receptors. J Biol Chem. 1993 Feb 15; 268(5):3044-7.
Score: 0.001
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An insulin-like growth factor I/insulin hybrid exhibiting high potency for interaction with the type I insulin-like growth factor and insulin receptors of placental plasma membranes. J Biol Chem. 1990 Oct 15; 265(29):17820-5.
Score: 0.001