Raghu Mirmira to Islets of Langerhans
This is a "connection" page, showing publications Raghu Mirmira has written about Islets of Langerhans.
Connection Strength
7.044
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Distinct gene expression pathways in islets from individuals with short- and long-duration type 1 diabetes. Diabetes Obes Metab. 2018 08; 20(8):1859-1867.
Score: 0.478
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Measurement of Differentially Methylated INS DNA Species in Human Serum Samples as a Biomarker of Islet ß Cell Death. J Vis Exp. 2016 12 21; (118).
Score: 0.437
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Maintenance of Pdx1 mRNA translation in islet ß-cells during the unfolded protein response. Mol Endocrinol. 2014 Nov; 28(11):1820-30.
Score: 0.374
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12-lipoxygenase promotes obesity-induced oxidative stress in pancreatic islets. Mol Cell Biol. 2014 Oct 01; 34(19):3735-45.
Score: 0.370
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From immunobiology to ß-cell biology: the changing perspective on type 1 diabetes. Islets. 2014; 6(2):e28778.
Score: 0.355
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Mouse islet of Langerhans isolation using a combination of purified collagenase and neutral protease. J Vis Exp. 2012 Sep 07; (67).
Score: 0.324
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The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice. J Clin Invest. 2010 Jun; 120(6):2156-70.
Score: 0.277
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Expression and function of Set7/9 in pancreatic islets. Islets. 2009 Nov-Dec; 1(3):269-72.
Score: 0.266
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Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure. Mol Cell Biol. 2009 Apr; 29(8):2053-67.
Score: 0.254
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Methyltransferase Set7/9 maintains transcription and euchromatin structure at islet-enriched genes. Diabetes. 2009 Jan; 58(1):185-93.
Score: 0.249
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A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis. Mol Genet Metab. 2007 Sep-Oct; 92(1-2):43-55.
Score: 0.228
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Glucose regulation of insulin gene transcription and pre-mRNA processing in human islets. Diabetes. 2007 Mar; 56(3):827-35.
Score: 0.221
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The C-terminal domain of the beta cell homeodomain factor Nkx6.1 enhances sequence-selective DNA binding at the insulin promoter. Biochemistry. 2005 Aug 23; 44(33):11269-78.
Score: 0.199
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Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes. J Biol Chem. 2005 Apr 29; 280(17):16798-807.
Score: 0.193
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The transcriptional repressor Nkx6.1 also functions as a deoxyribonucleic acid context-dependent transcriptional activator during pancreatic beta-cell differentiation: evidence for feedback activation of the nkx6.1 gene by Nkx6.1. Mol Endocrinol. 2004 Jun; 18(6):1363-75.
Score: 0.181
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Covalent histone modifications underlie the developmental regulation of insulin gene transcription in pancreatic beta cells. J Biol Chem. 2003 Jun 27; 278(26):23617-23.
Score: 0.169
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Transcription factors direct the development and function of pancreatic beta cells. Trends Endocrinol Metab. 2003 Mar; 14(2):78-84.
Score: 0.168
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Circulating unmethylated CHTOP and INS DNA fragments provide evidence of possible islet cell death in youth with obesity and diabetes. Clin Epigenetics. 2020 07 31; 12(1):116.
Score: 0.140
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Beta-cell differentiation factor Nkx6.1 contains distinct DNA binding interference and transcriptional repression domains. J Biol Chem. 2000 May 12; 275(19):14743-51.
Score: 0.138
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Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention. Cell Metab. 2020 02 04; 31(2):363-374.e6.
Score: 0.135
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Profiling of RNAs from Human Islet-Derived Exosomes in a Model of Type 1 Diabetes. Int J Mol Sci. 2019 11 25; 20(23).
Score: 0.134
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Abnormalities in proinsulin processing in islets from individuals with longstanding T1D. Transl Res. 2019 11; 213:90-99.
Score: 0.131
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A Versatile, Portable Intravital Microscopy Platform for Studying Beta-cell Biology In Vivo. Sci Rep. 2019 06 11; 9(1):8449.
Score: 0.130
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Biomarkers of islet beta cell stress and death in type 1 diabetes. Diabetologia. 2018 11; 61(11):2259-2265.
Score: 0.122
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In situ type I oligomeric collagen macroencapsulation promotes islet longevity and function in vitro and in vivo. Am J Physiol Endocrinol Metab. 2018 10 01; 315(4):E650-E661.
Score: 0.121
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Comparative quantitative proteomic analysis of disease stratified laser captured microdissected human islets identifies proteins and pathways potentially related to type 1 diabetes. PLoS One. 2017; 12(9):e0183908.
Score: 0.115
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12-Lipoxygenase Inhibitor Improves Functions of Cytokine-Treated Human Islets and Type 2 Diabetic Islets. J Clin Endocrinol Metab. 2017 08 01; 102(8):2789-2797.
Score: 0.114
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SET7/9 Enzyme Regulates Cytokine-induced Expression of Inducible Nitric-oxide Synthase through Methylation of Lysine 4 at Histone 3 in the Islet ß Cell. J Biol Chem. 2015 Jul 03; 290(27):16607-18.
Score: 0.098
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Syntaxin 4 up-regulation increases efficiency of insulin release in pancreatic islets from humans with and without type 2 diabetes mellitus. J Clin Endocrinol Metab. 2014 May; 99(5):E866-70.
Score: 0.090
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Mouse and human islets survive and function after coating by biosilicification. Am J Physiol Endocrinol Metab. 2013 Nov 15; 305(10):E1230-40.
Score: 0.087
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AGI-1067, a novel antioxidant and anti-inflammatory agent, enhances insulin release and protects mouse islets. Mol Cell Endocrinol. 2010 Jul 29; 323(2):246-55.
Score: 0.068
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Liver X receptor agonists augment human islet function through activation of anaplerotic pathways and glycerolipid/free fatty acid cycling. J Biol Chem. 2010 Feb 19; 285(8):5392-404.
Score: 0.067
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Differential expression of cell cycle proteins during ageing of pancreatic islet cells. Diabetes Obes Metab. 2008 Nov; 10 Suppl 4:136-46.
Score: 0.062
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Research resource: nuclear hormone receptor expression in the endocrine pancreas. Mol Endocrinol. 2008 Oct; 22(10):2353-63.
Score: 0.061
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Trefoil factor 3 stimulates human and rodent pancreatic islet beta-cell replication with retention of function. Mol Endocrinol. 2008 May; 22(5):1251-9.
Score: 0.059
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Pdx-1 links histone H3-Lys-4 methylation to RNA polymerase II elongation during activation of insulin transcription. J Biol Chem. 2005 Oct 28; 280(43):36244-53.
Score: 0.050
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The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells. Proc Natl Acad Sci U S A. 2005 May 17; 102(20):7297-302.
Score: 0.049
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Proendocrine genes coordinate the pancreatic islet differentiation program in vitro. Proc Natl Acad Sci U S A. 2004 Sep 07; 101(36):13245-50.
Score: 0.047
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Quantitative assessment of gene targeting in vitro and in vivo by the pancreatic transcription factor, Pdx1. Importance of chromatin structure in directing promoter binding. J Biol Chem. 2002 Apr 12; 277(15):13286-93.
Score: 0.039
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Regulation of the pancreatic pro-endocrine gene neurogenin3. Diabetes. 2001 May; 50(5):928-36.
Score: 0.037
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Transcriptional and translational regulation of beta-cell differentiation factor Nkx6.1. J Biol Chem. 2000 Nov 03; 275(44):34224-30.
Score: 0.036
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Oligomeric collagen as an encapsulation material for islet/ß-cell replacement: effect of islet source, dose, implant site, and administration format. Am J Physiol Endocrinol Metab. 2020 08 01; 319(2):E388-E400.
Score: 0.035
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1,25-Dihydroxyvitamin D3 enhances glucose-stimulated insulin secretion in mouse and human islets: a role for transcriptional regulation of voltage-gated calcium channels by the vitamin D receptor. J Steroid Biochem Mol Biol. 2019 01; 185:17-26.
Score: 0.031
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IFN-a induces a preferential long-lasting expression of MHC class I in human pancreatic beta cells. Diabetologia. 2018 03; 61(3):636-640.
Score: 0.029
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Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells. Diabetologia. 2016 Jan; 59(1):151-160.
Score: 0.026
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Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-Alox15(null) mice, leading to protection against type 1 diabetes development. PLoS One. 2013; 8(2):e56763.
Score: 0.021
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The roles of ATF3, an adaptive-response gene, in high-fat-diet-induced diabetes and pancreatic beta-cell dysfunction. Mol Endocrinol. 2010 Jul; 24(7):1423-33.
Score: 0.017
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Cyclical and alternating infusions of glucose and intralipid in rats inhibit insulin gene expression and Pdx-1 binding in islets. Diabetes. 2008 Feb; 57(2):424-31.
Score: 0.015