Raghu Mirmira to Mice
This is a "connection" page, showing publications Raghu Mirmira has written about Mice.
Connection Strength
1.572
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Phenotypic sexual dimorphism in response to dietary fat manipulation in C57BL/6J mice. J Diabetes Complications. 2021 02; 35(2):107795.
Score: 0.069
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Hypusinated eIF5A is expressed in the pancreas and spleen of individuals with type 1 and type 2 diabetes. PLoS One. 2020; 15(3):e0230627.
Score: 0.066
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Inhibition of 12/15-Lipoxygenase Protects Against ß-Cell Oxidative Stress and Glycemic Deterioration in Mouse Models of Type 1 Diabetes. Diabetes. 2017 11; 66(11):2875-2887.
Score: 0.055
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Peroxisome Proliferator-activated Receptor-? Activation Augments the ß-Cell Unfolded Protein Response and Rescues Early Glycemic Deterioration and ß Cell Death in Non-obese Diabetic Mice. J Biol Chem. 2016 Oct 21; 291(43):22524-22533.
Score: 0.052
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Maintenance of Pdx1 mRNA translation in islet ß-cells during the unfolded protein response. Mol Endocrinol. 2014 Nov; 28(11):1820-30.
Score: 0.045
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12-lipoxygenase promotes obesity-induced oxidative stress in pancreatic islets. Mol Cell Biol. 2014 Oct 01; 34(19):3735-45.
Score: 0.045
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Palmitate induces mRNA translation and increases ER protein load in islet ß-cells via activation of the mammalian target of rapamycin pathway. Diabetes. 2014 Oct; 63(10):3404-15.
Score: 0.044
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Deoxyhypusine synthase promotes differentiation and proliferation of T helper type 1 (Th1) cells in autoimmune diabetes. J Biol Chem. 2013 Dec 20; 288(51):36226-35.
Score: 0.042
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Protective effects of polyamine depletion in mouse models of type 1 diabetes: implications for therapy. Amino Acids. 2014 Mar; 46(3):633-42.
Score: 0.042
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Effects of combination therapy with dipeptidyl peptidase-IV and histone deacetylase inhibitors in the non-obese diabetic mouse model of type 1 diabetes. Clin Exp Immunol. 2013 Jun; 172(3):375-82.
Score: 0.041
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Translational control of inducible nitric oxide synthase by p38 MAPK in islet ß-cells. Mol Endocrinol. 2013 Feb; 27(2):336-49.
Score: 0.040
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Targeting regulatory T cells in the treatment of type 1 diabetes mellitus. Curr Mol Med. 2012 Dec; 12(10):1261-72.
Score: 0.040
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Mouse islet of Langerhans isolation using a combination of purified collagenase and neutral protease. J Vis Exp. 2012 Sep 07; (67).
Score: 0.039
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Islet ß-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model. Diabetes. 2012 Apr; 61(4):818-27.
Score: 0.038
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Deoxyhypusine synthase haploinsufficiency attenuates acute cytokine signaling. Cell Cycle. 2011 Apr 01; 10(7):1043-9.
Score: 0.035
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Inhibition of deoxyhypusine synthase enhances islet {beta} cell function and survival in the setting of endoplasmic reticulum stress and type 2 diabetes. J Biol Chem. 2010 Dec 17; 285(51):39943-52.
Score: 0.034
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The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice. J Clin Invest. 2010 Jun; 120(6):2156-70.
Score: 0.033
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Inducible pluripotent stem cells: not quite ready for prime time? Curr Opin Organ Transplant. 2010 Feb; 15(1):61-7.
Score: 0.033
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Expression and function of Set7/9 in pancreatic islets. Islets. 2009 Nov-Dec; 1(3):269-72.
Score: 0.032
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Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure. Mol Cell Biol. 2009 Apr; 29(8):2053-67.
Score: 0.031
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Development of insulin-producing cells from primitive biologic precursors. Curr Opin Organ Transplant. 2009 Feb; 14(1):56-63.
Score: 0.031
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Noninvasive assessment of pancreatic beta-cell function in vivo with manganese-enhanced magnetic resonance imaging. Am J Physiol Endocrinol Metab. 2009 Mar; 296(3):E573-8.
Score: 0.030
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Methyltransferase Set7/9 maintains transcription and euchromatin structure at islet-enriched genes. Diabetes. 2009 Jan; 58(1):185-93.
Score: 0.030
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Pdx1 and BETA2/NeuroD1 participate in a transcriptional complex that mediates short-range DNA looping at the insulin gene. J Biol Chem. 2008 Mar 28; 283(13):8164-72.
Score: 0.029
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Role of chromatin accessibility in the occupancy and transcription of the insulin gene by the pancreatic and duodenal homeobox factor 1. Mol Endocrinol. 2006 Dec; 20(12):3133-45.
Score: 0.026
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Pdx-1 links histone H3-Lys-4 methylation to RNA polymerase II elongation during activation of insulin transcription. J Biol Chem. 2005 Oct 28; 280(43):36244-53.
Score: 0.024
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The C-terminal domain of the beta cell homeodomain factor Nkx6.1 enhances sequence-selective DNA binding at the insulin promoter. Biochemistry. 2005 Aug 23; 44(33):11269-78.
Score: 0.024
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Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes. J Biol Chem. 2005 Apr 29; 280(17):16798-807.
Score: 0.023
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The transcriptional repressor Nkx6.1 also functions as a deoxyribonucleic acid context-dependent transcriptional activator during pancreatic beta-cell differentiation: evidence for feedback activation of the nkx6.1 gene by Nkx6.1. Mol Endocrinol. 2004 Jun; 18(6):1363-75.
Score: 0.022
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Covalent histone modifications underlie the developmental regulation of insulin gene transcription in pancreatic beta cells. J Biol Chem. 2003 Jun 27; 278(26):23617-23.
Score: 0.020
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Quantitative assessment of gene targeting in vitro and in vivo by the pancreatic transcription factor, Pdx1. Importance of chromatin structure in directing promoter binding. J Biol Chem. 2002 Apr 12; 277(15):13286-93.
Score: 0.019
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Hypusination Orchestrates the Antimicrobial Response of Macrophages. Cell Rep. 2020 12 15; 33(11):108510.
Score: 0.017
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Oligomeric collagen as an encapsulation material for islet/ß-cell replacement: effect of islet source, dose, implant site, and administration format. Am J Physiol Endocrinol Metab. 2020 08 01; 319(2):E388-E400.
Score: 0.017
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Beta-cell differentiation factor Nkx6.1 contains distinct DNA binding interference and transcriptional repression domains. J Biol Chem. 2000 May 12; 275(19):14743-51.
Score: 0.017
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Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention. Cell Metab. 2020 02 04; 31(2):363-374.e6.
Score: 0.016
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Hypusine biosynthesis in ß cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis. Sci Signal. 2019 12 03; 12(610).
Score: 0.016
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A Versatile, Portable Intravital Microscopy Platform for Studying Beta-cell Biology In Vivo. Sci Rep. 2019 06 11; 9(1):8449.
Score: 0.016
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Platelet-type 12-lipoxygenase deletion provokes a compensatory 12/15-lipoxygenase increase that exacerbates oxidative stress in mouse islet ß cells. J Biol Chem. 2019 04 19; 294(16):6612-6620.
Score: 0.015
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eIF5A inhibition influences T cell dynamics in the pancreatic microenvironment of the humanized mouse model of Type 1 Diabetes. Sci Rep. 2019 02 07; 9(1):1533.
Score: 0.015
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1,25-Dihydroxyvitamin D3 enhances glucose-stimulated insulin secretion in mouse and human islets: a role for transcriptional regulation of voltage-gated calcium channels by the vitamin D receptor. J Steroid Biochem Mol Biol. 2019 01; 185:17-26.
Score: 0.015
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In situ type I oligomeric collagen macroencapsulation promotes islet longevity and function in vitro and in vivo. Am J Physiol Endocrinol Metab. 2018 10 01; 315(4):E650-E661.
Score: 0.015
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A system for detecting high impact-low frequency mutations in primary tumors and metastases. Oncogene. 2018 01 11; 37(2):185-196.
Score: 0.014
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Loss of mTORC1 signalling impairs ß-cell homeostasis and insulin processing. Nat Commun. 2017 07 12; 8:16014.
Score: 0.014
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Chronic high fat feeding restricts islet mRNA translation initiation independently of ER stress via DNA damage and p53 activation. Sci Rep. 2017 06 19; 7(1):3758.
Score: 0.014
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IRS1 deficiency protects ß-cells against ER stress-induced apoptosis by modulating sXBP-1 stability and protein translation. Sci Rep. 2016 07 05; 6:28177.
Score: 0.013
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Loss of Free Fatty Acid Receptor 2 leads to impaired islet mass and beta cell survival. Sci Rep. 2016 06 21; 6:28159.
Score: 0.013
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Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells. Diabetologia. 2016 Jan; 59(1):151-160.
Score: 0.012
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Proinsulin and heat shock protein 90 as biomarkers of beta-cell stress in the early period after onset of type 1 diabetes. Transl Res. 2016 Feb; 168:96-106.e1.
Score: 0.012
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SET7/9 Enzyme Regulates Cytokine-induced Expression of Inducible Nitric-oxide Synthase through Methylation of Lysine 4 at Histone 3 in the Islet ß Cell. J Biol Chem. 2015 Jul 03; 290(27):16607-18.
Score: 0.012
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Transcriptional activity of the islet ß cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9. J Biol Chem. 2015 Apr 10; 290(15):9812-22.
Score: 0.012
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Leukotriene B4-mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of type 1 diabetes. Sci Signal. 2015 Jan 27; 8(361):ra10.
Score: 0.012
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Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic ß cells. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):E2319-28.
Score: 0.011
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Syntaxin 4 up-regulation increases efficiency of insulin release in pancreatic islets from humans with and without type 2 diabetes mellitus. J Clin Endocrinol Metab. 2014 May; 99(5):E866-70.
Score: 0.011
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Eukaryotic translation initiation factor 5A inhibition alters physiopathology and immune responses in a "humanized" transgenic mouse model of type 1 diabetes. Am J Physiol Endocrinol Metab. 2014 Apr 01; 306(7):E791-8.
Score: 0.011
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Divergent compensatory responses to high-fat diet between C57BL6/J and C57BLKS/J inbred mouse strains. Am J Physiol Endocrinol Metab. 2013 Dec; 305(12):E1495-511.
Score: 0.011
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Mouse and human islets survive and function after coating by biosilicification. Am J Physiol Endocrinol Metab. 2013 Nov 15; 305(10):E1230-40.
Score: 0.010
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Detection of islet ß-cell death in vivo by multiplex PCR analysis of differentially methylated DNA. Endocrinology. 2013 Sep; 154(9):3476-81.
Score: 0.010
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Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-Alox15(null) mice, leading to protection against type 1 diabetes development. PLoS One. 2013; 8(2):e56763.
Score: 0.010
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Mitogen-inducible gene 6 triggers apoptosis and exacerbates ER stress-induced ß-cell death. Mol Endocrinol. 2013 Jan; 27(1):162-71.
Score: 0.010
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?40 Isoform of p53 controls ß-cell proliferation and glucose homeostasis in mice. Diabetes. 2011 Apr; 60(4):1210-22.
Score: 0.009
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Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain. Mol Cell Biol. 2010 Sep; 30(17):4234-44.
Score: 0.008
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An intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic beta cells. J Clin Invest. 2010 Jul; 120(7):2575-89.
Score: 0.008
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The roles of ATF3, an adaptive-response gene, in high-fat-diet-induced diabetes and pancreatic beta-cell dysfunction. Mol Endocrinol. 2010 Jul; 24(7):1423-33.
Score: 0.008
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AGI-1067, a novel antioxidant and anti-inflammatory agent, enhances insulin release and protects mouse islets. Mol Cell Endocrinol. 2010 Jul 29; 323(2):246-55.
Score: 0.008
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Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress. Proc Natl Acad Sci U S A. 2009 Nov 10; 106(45):19090-5.
Score: 0.008
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Research resource: nuclear hormone receptor expression in the endocrine pancreas. Mol Endocrinol. 2008 Oct; 22(10):2353-63.
Score: 0.007
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Proendocrine genes coordinate the pancreatic islet differentiation program in vitro. Proc Natl Acad Sci U S A. 2004 Sep 07; 101(36):13245-50.
Score: 0.006
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Regulation of the pancreatic pro-endocrine gene neurogenin3. Diabetes. 2001 May; 50(5):928-36.
Score: 0.004