Raghu Mirmira to Insulin-Secreting Cells
This is a "connection" page, showing publications Raghu Mirmira has written about Insulin-Secreting Cells.
Connection Strength
9.657
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Preclinical evaluation of tyrosine kinase 2 inhibitors for human beta-cell protection in type 1 diabetes. Diabetes Obes Metab. 2020 10; 22(10):1827-1836.
Score: 0.551
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Inhibition of 12/15-Lipoxygenase Protects Against ß-Cell Oxidative Stress and Glycemic Deterioration in Mouse Models of Type 1 Diabetes. Diabetes. 2017 11; 66(11):2875-2887.
Score: 0.452
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Biomarkers of ß-Cell Stress and Death in Type 1 Diabetes. Curr Diab Rep. 2016 10; 16(10):95.
Score: 0.425
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Peroxisome Proliferator-activated Receptor-? Activation Augments the ß-Cell Unfolded Protein Response and Rescues Early Glycemic Deterioration and ß Cell Death in Non-obese Diabetic Mice. J Biol Chem. 2016 Oct 21; 291(43):22524-22533.
Score: 0.423
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Minireview: 12-Lipoxygenase and Islet ß-Cell Dysfunction in Diabetes. Mol Endocrinol. 2015 Jun; 29(6):791-800.
Score: 0.382
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Maintenance of Pdx1 mRNA translation in islet ß-cells during the unfolded protein response. Mol Endocrinol. 2014 Nov; 28(11):1820-30.
Score: 0.369
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Palmitate induces mRNA translation and increases ER protein load in islet ß-cells via activation of the mammalian target of rapamycin pathway. Diabetes. 2014 Oct; 63(10):3404-15.
Score: 0.360
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Lost in translation: endoplasmic reticulum stress and the decline of ß-cell health in diabetes mellitus. Diabetes Obes Metab. 2013 Sep; 15 Suppl 3:159-69.
Score: 0.343
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Achieving "PeaK-A" insulin secretion. Diabetes. 2013 May; 62(5):1389-90.
Score: 0.335
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Translational control of inducible nitric oxide synthase by p38 MAPK in islet ß-cells. Mol Endocrinol. 2013 Feb; 27(2):336-49.
Score: 0.327
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Saturated free fatty acids: islet ß cell "stressERs". Endocrine. 2012 Aug; 42(1):1-2.
Score: 0.318
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Islet ß-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model. Diabetes. 2012 Apr; 61(4):818-27.
Score: 0.311
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Deoxyhypusine synthase haploinsufficiency attenuates acute cytokine signaling. Cell Cycle. 2011 Apr 01; 10(7):1043-9.
Score: 0.290
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Inhibition of deoxyhypusine synthase enhances islet {beta} cell function and survival in the setting of endoplasmic reticulum stress and type 2 diabetes. J Biol Chem. 2010 Dec 17; 285(51):39943-52.
Score: 0.281
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Development of insulin-producing cells from primitive biologic precursors. Curr Opin Organ Transplant. 2009 Feb; 14(1):56-63.
Score: 0.250
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Noninvasive assessment of pancreatic beta-cell function in vivo with manganese-enhanced magnetic resonance imaging. Am J Physiol Endocrinol Metab. 2009 Mar; 296(3):E573-8.
Score: 0.248
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Role of chromatin accessibility in the occupancy and transcription of the insulin gene by the pancreatic and duodenal homeobox factor 1. Mol Endocrinol. 2006 Dec; 20(12):3133-45.
Score: 0.210
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The role of beta-cell dysfunction in early type 1 diabetes. Curr Opin Endocrinol Diabetes Obes. 2020 08; 27(4):215-224.
Score: 0.138
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Hypusinated eIF5A is expressed in the pancreas and spleen of individuals with type 1 and type 2 diabetes. PLoS One. 2020; 15(3):e0230627.
Score: 0.135
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Circulating Unmethylated Insulin DNA As a Biomarker of Human Beta Cell Death: A Multi-laboratory Assay Comparison. J Clin Endocrinol Metab. 2020 03 01; 105(3).
Score: 0.135
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Hypusine biosynthesis in ß cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis. Sci Signal. 2019 12 03; 12(610).
Score: 0.132
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The role of proteomics in assessing beta-cell dysfunction and death in type 1 diabetes. Expert Rev Proteomics. 2019 07; 16(7):569-582.
Score: 0.128
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A Versatile, Portable Intravital Microscopy Platform for Studying Beta-cell Biology In Vivo. Sci Rep. 2019 06 11; 9(1):8449.
Score: 0.128
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Platelet-type 12-lipoxygenase deletion provokes a compensatory 12/15-lipoxygenase increase that exacerbates oxidative stress in mouse islet ß cells. J Biol Chem. 2019 04 19; 294(16):6612-6620.
Score: 0.125
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Analysis of serum Hsp90 as a potential biomarker of ß cell autoimmunity in type 1 diabetes. PLoS One. 2019; 14(1):e0208456.
Score: 0.124
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Biomarkers of islet beta cell stress and death in type 1 diabetes. Diabetologia. 2018 11; 61(11):2259-2265.
Score: 0.121
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Immune reconstitution in ART treated, but not untreated HIV infection, is associated with abnormal beta cell function. PLoS One. 2018; 13(5):e0197080.
Score: 0.119
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Interleukin-6 Reduces ß-Cell Oxidative Stress by Linking Autophagy With the Antioxidant Response. Diabetes. 2018 08; 67(8):1576-1588.
Score: 0.119
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An In Vivo Zebrafish Model for Interrogating ROS-Mediated Pancreatic ß-Cell Injury, Response, and Prevention. Oxid Med Cell Longev. 2018; 2018:1324739.
Score: 0.118
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IFN-a induces a preferential long-lasting expression of MHC class I in human pancreatic beta cells. Diabetologia. 2018 03; 61(3):636-640.
Score: 0.116
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Loss of mTORC1 signalling impairs ß-cell homeostasis and insulin processing. Nat Commun. 2017 07 12; 8:16014.
Score: 0.112
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Chronic high fat feeding restricts islet mRNA translation initiation independently of ER stress via DNA damage and p53 activation. Sci Rep. 2017 06 19; 7(1):3758.
Score: 0.112
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IRS1 deficiency protects ß-cells against ER stress-induced apoptosis by modulating sXBP-1 stability and protein translation. Sci Rep. 2016 07 05; 6:28177.
Score: 0.104
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Loss of Free Fatty Acid Receptor 2 leads to impaired islet mass and beta cell survival. Sci Rep. 2016 06 21; 6:28159.
Score: 0.104
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Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells. Diabetologia. 2016 Jan; 59(1):151-160.
Score: 0.101
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Proinsulin and heat shock protein 90 as biomarkers of beta-cell stress in the early period after onset of type 1 diabetes. Transl Res. 2016 Feb; 168:96-106.e1.
Score: 0.099
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Transcriptional activity of the islet ß cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9. J Biol Chem. 2015 Apr 10; 290(15):9812-22.
Score: 0.095
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12-lipoxygenase promotes obesity-induced oxidative stress in pancreatic islets. Mol Cell Biol. 2014 Oct 01; 34(19):3735-45.
Score: 0.091
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Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic ß cells. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):E2319-28.
Score: 0.090
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Detection of islet ß-cell death in vivo by multiplex PCR analysis of differentially methylated DNA. Endocrinology. 2013 Sep; 154(9):3476-81.
Score: 0.085
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Effects of combination therapy with dipeptidyl peptidase-IV and histone deacetylase inhibitors in the non-obese diabetic mouse model of type 1 diabetes. Clin Exp Immunol. 2013 Jun; 172(3):375-82.
Score: 0.084
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Targeting regulatory T cells in the treatment of type 1 diabetes mellitus. Curr Mol Med. 2012 Dec; 12(10):1261-72.
Score: 0.081
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Mitogen-inducible gene 6 triggers apoptosis and exacerbates ER stress-induced ß-cell death. Mol Endocrinol. 2013 Jan; 27(1):162-71.
Score: 0.081
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?40 Isoform of p53 controls ß-cell proliferation and glucose homeostasis in mice. Diabetes. 2011 Apr; 60(4):1210-22.
Score: 0.072
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Oscillatory glucose flux in INS 1 pancreatic ß cells: a self-referencing microbiosensor study. Anal Biochem. 2011 Apr 15; 411(2):185-93.
Score: 0.071
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Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain. Mol Cell Biol. 2010 Sep; 30(17):4234-44.
Score: 0.069
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The roles of ATF3, an adaptive-response gene, in high-fat-diet-induced diabetes and pancreatic beta-cell dysfunction. Mol Endocrinol. 2010 Jul; 24(7):1423-33.
Score: 0.068
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Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress. Proc Natl Acad Sci U S A. 2009 Nov 10; 106(45):19090-5.
Score: 0.066
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Methyltransferase Set7/9 maintains transcription and euchromatin structure at islet-enriched genes. Diabetes. 2009 Jan; 58(1):185-93.
Score: 0.061
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Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1. Mol Cell Biol. 2008 May; 28(10):3465-76.
Score: 0.059
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Trefoil factor 3 stimulates human and rodent pancreatic islet beta-cell replication with retention of function. Mol Endocrinol. 2008 May; 22(5):1251-9.
Score: 0.058
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Pdx1 and BETA2/NeuroD1 participate in a transcriptional complex that mediates short-range DNA looping at the insulin gene. J Biol Chem. 2008 Mar 28; 283(13):8164-72.
Score: 0.058
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Pdx-1 links histone H3-Lys-4 methylation to RNA polymerase II elongation during activation of insulin transcription. J Biol Chem. 2005 Oct 28; 280(43):36244-53.
Score: 0.049
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Oligomeric collagen as an encapsulation material for islet/ß-cell replacement: effect of islet source, dose, implant site, and administration format. Am J Physiol Endocrinol Metab. 2020 08 01; 319(2):E388-E400.
Score: 0.034
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eIF5A inhibition influences T cell dynamics in the pancreatic microenvironment of the humanized mouse model of Type 1 Diabetes. Sci Rep. 2019 02 07; 9(1):1533.
Score: 0.031
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Role of the 12-lipoxygenase pathway in diabetes pathogenesis and complications. Pharmacol Ther. 2019 03; 195:100-110.
Score: 0.031
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Persistent elevations in circulating INS DNA among subjects with longstanding type 1 diabetes. Diabetes Obes Metab. 2019 01; 21(1):95-102.
Score: 0.030
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1,25-Dihydroxyvitamin D3 enhances glucose-stimulated insulin secretion in mouse and human islets: a role for transcriptional regulation of voltage-gated calcium channels by the vitamin D receptor. J Steroid Biochem Mol Biol. 2019 01; 185:17-26.
Score: 0.030
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Elevated unmethylated and methylated insulin DNA are unique markers of A+ß+ ketosis prone diabetes. J Diabetes Complications. 2018 02; 32(2):193-195.
Score: 0.029
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Polyamine biosynthesis is critical for growth and differentiation of the pancreas. Sci Rep. 2015 Aug 24; 5:13269.
Score: 0.025
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SET7/9 Enzyme Regulates Cytokine-induced Expression of Inducible Nitric-oxide Synthase through Methylation of Lysine 4 at Histone 3 in the Islet ß Cell. J Biol Chem. 2015 Jul 03; 290(27):16607-18.
Score: 0.024
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Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-Alox15(null) mice, leading to protection against type 1 diabetes development. PLoS One. 2013; 8(2):e56763.
Score: 0.021
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An intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic beta cells. J Clin Invest. 2010 Jul; 120(7):2575-89.
Score: 0.017