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Connection

Raghu Mirmira to Homeodomain Proteins

This is a "connection" page, showing publications Raghu Mirmira has written about Homeodomain Proteins.
Connection Strength

2.849
  1. Maintenance of Pdx1 mRNA translation in islet ß-cells during the unfolded protein response. Mol Endocrinol. 2014 Nov; 28(11):1820-30.
    View in: PubMed
    Score: 0.363
  2. Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure. Mol Cell Biol. 2009 Apr; 29(8):2053-67.
    View in: PubMed
    Score: 0.247
  3. Pdx1 and BETA2/NeuroD1 participate in a transcriptional complex that mediates short-range DNA looping at the insulin gene. J Biol Chem. 2008 Mar 28; 283(13):8164-72.
    View in: PubMed
    Score: 0.229
  4. A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis. Mol Genet Metab. 2007 Sep-Oct; 92(1-2):43-55.
    View in: PubMed
    Score: 0.221
  5. Role of chromatin accessibility in the occupancy and transcription of the insulin gene by the pancreatic and duodenal homeobox factor 1. Mol Endocrinol. 2006 Dec; 20(12):3133-45.
    View in: PubMed
    Score: 0.207
  6. Pdx-1 links histone H3-Lys-4 methylation to RNA polymerase II elongation during activation of insulin transcription. J Biol Chem. 2005 Oct 28; 280(43):36244-53.
    View in: PubMed
    Score: 0.194
  7. The C-terminal domain of the beta cell homeodomain factor Nkx6.1 enhances sequence-selective DNA binding at the insulin promoter. Biochemistry. 2005 Aug 23; 44(33):11269-78.
    View in: PubMed
    Score: 0.194
  8. Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes. J Biol Chem. 2005 Apr 29; 280(17):16798-807.
    View in: PubMed
    Score: 0.187
  9. The transcriptional repressor Nkx6.1 also functions as a deoxyribonucleic acid context-dependent transcriptional activator during pancreatic beta-cell differentiation: evidence for feedback activation of the nkx6.1 gene by Nkx6.1. Mol Endocrinol. 2004 Jun; 18(6):1363-75.
    View in: PubMed
    Score: 0.176
  10. Quantitative assessment of gene targeting in vitro and in vivo by the pancreatic transcription factor, Pdx1. Importance of chromatin structure in directing promoter binding. J Biol Chem. 2002 Apr 12; 277(15):13286-93.
    View in: PubMed
    Score: 0.151
  11. Beta-cell differentiation factor Nkx6.1 contains distinct DNA binding interference and transcriptional repression domains. J Biol Chem. 2000 May 12; 275(19):14743-51.
    View in: PubMed
    Score: 0.134
  12. Transcriptional activity of the islet ß cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9. J Biol Chem. 2015 Apr 10; 290(15):9812-22.
    View in: PubMed
    Score: 0.094
  13. Expression and function of Set7/9 in pancreatic islets. Islets. 2009 Nov-Dec; 1(3):269-72.
    View in: PubMed
    Score: 0.065
  14. Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress. Proc Natl Acad Sci U S A. 2009 Nov 10; 106(45):19090-5.
    View in: PubMed
    Score: 0.065
  15. Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1. Mol Cell Biol. 2008 May; 28(10):3465-76.
    View in: PubMed
    Score: 0.058
  16. Cyclical and alternating infusions of glucose and intralipid in rats inhibit insulin gene expression and Pdx-1 binding in islets. Diabetes. 2008 Feb; 57(2):424-31.
    View in: PubMed
    Score: 0.056
  17. The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells. Proc Natl Acad Sci U S A. 2005 May 17; 102(20):7297-302.
    View in: PubMed
    Score: 0.047
  18. Transcriptional and translational regulation of beta-cell differentiation factor Nkx6.1. J Biol Chem. 2000 Nov 03; 275(44):34224-30.
    View in: PubMed
    Score: 0.035
  19. Intramolecular control of transcriptional activity by the NK2-specific domain in NK-2 homeodomain proteins. Proc Natl Acad Sci U S A. 2000 Aug 15; 97(17):9443-8.
    View in: PubMed
    Score: 0.034
  20. Chronic high fat feeding restricts islet mRNA translation initiation independently of ER stress via DNA damage and p53 activation. Sci Rep. 2017 06 19; 7(1):3758.
    View in: PubMed
    Score: 0.027
  21. Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic ß cells. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):E2319-28.
    View in: PubMed
    Score: 0.022
  22. Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain. Mol Cell Biol. 2010 Sep; 30(17):4234-44.
    View in: PubMed
    Score: 0.017
  23. Liver X receptor agonists augment human islet function through activation of anaplerotic pathways and glycerolipid/free fatty acid cycling. J Biol Chem. 2010 Feb 19; 285(8):5392-404.
    View in: PubMed
    Score: 0.016
  24. The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter. Mol Cell Biol. 2000 Feb; 20(3):900-11.
    View in: PubMed
    Score: 0.008
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.