31776290Tang AT, Sullivan KR, Hong CC, Goddard LM, Mahadevan A, Ren A, Pardo H, Peiper A, Griffin E, Tanes C, Mattei LM, Yang J, Li L, Mericko-Ishizuka P, Shen L, Hobson N, Girard R, Lightle R, Moore T, Shenkar R, Polster SP, Rödel CJ, Li N, Zhu Q, Whitehead KJ, Zheng X, Akers A, Morrison L, Kim H, Bittinger K, Lengner CJ, Schwaninger M, Velcich A, Augenlicht L, Abdelilah-Seyfried S, Min W, Marchuk DA, Awad IA, Kahn MLScience translational medicineApoptosis Regulatory Proteins; Brain; Gastrointestinal Tract; Hemangioma, Cavernous, Central Nervous System; Membrane Proteins; Proto-Oncogene ProteinsAnimals; Carrier Proteins; Colitis; Dexamethasone; Dextran Sulfate; Endothelial Cells; Epithelial Cells; Gastrointestinal Microbiome; Humans; Intestinal Mucosa; KRIT1 Protein; Ligands; Mice; Signal Transduction; Toll-Like Receptor 4Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation. Sci Transl Med. 2019 11 27; 11(520).Sci Transl Med2019-11-27T00:00:002019Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation.prns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:orcidIdORCID idPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD000818Living Beings1457265180.249646AnimalsD001921Anatomy49222110.472384BrainD003092Disorders802360.788868ColitisD003907Chemicals & Drugs1313260.864786DexamethasoneD004847Anatomy2496620.724867Epithelial CellsSurgery-General SurgeryD008565Chemicals & Drugs37111940.607165Membrane ProteinsRomualdGirardRomuald Girard41.7886000000000087.598699999999993817Girard, RomualdResearch Assistant ProfessorD008024Chemicals & Drugs2034330.884665LigandsAuthorship 13454036Authorship 13454120Authorship 134542170.1850930.1850935authors10.2521has subject areaD011518Chemicals & Drugs2306450.750423Proto-Oncogene ProteinsD007413Anatomy1827880.679776Intestinal MucosaD006801Living Beings2262862810.130064HumansAuthorship 14156915D016264Chemicals & Drugs33680.975078Dextran SulfateNeurological SurgeryD051017Chemicals & Drugs961990.903941Apoptosis Regulatory ProteinsSeanPolsterSean Polster41.7886000000000087.598699999999994144Polster, Sean0000-0002-3229-5021Assistant ProfessorAuthorship 15347221D020786Disorders282230.784958Hemangioma, Cavernous, Central Nervous SystemD051379Living Beings980113130.368427MiceD051197Chemicals & Drugs57880.938266Toll-Like Receptor 4D042783Anatomy1474270.7883Endothelial CellsD002352Chemicals & Drugs2666720.751742Carrier ProteinsD0000691961134510.626605Gastrointestinal MicrobiomeD00007592711620.976632KRIT1 Proteinhttp://surgeryresearch.uchicago.edu/robert-shenkarRobert Shenkar, PhDD015398Physiology69932330.460071Signal TransductionD041981Anatomy1031910.839389Gastrointestinal TractUniversity of ChicagoLeShenLe Shen41.78927490000000-87.60125000000000411Shen, LeResearch Associate ProfessorIssamAwad3mN+CqU1DO/RmHllZ0mg9mHvIssam Awad41.78927490000000-87.60125000000000867Awad, IssamProfessorRobertShenkarRobert Shenkar41.78927490000000-87.60125000000000963Shenkar, RobertResearch Associate Professortrue1ProfessorProfessortrue1Research Associate ProfessorResearch Associate Professortrue1Research Assistant ProfessorResearch Assistant Professortrue1Assistant ProfessorAssistant Professortrue1Research Associate ProfessorResearch Associate Professor