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H2O2 production downstream of FLT3 is mediated by p22phox in the endoplasmic reticulum and is required for STAT5 signalling.
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H2O2 production downstream of FLT3 is mediated by p22phox in the endoplasmic reticulum and is required for STAT5 signalling.
H2O2 production downstream of FLT3 is mediated by p22phox in the endoplasmic reticulum and is required for STAT5 signalling. PLoS One. 2012; 7(7):e34050.
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PubMed
subject areas
Benzoxazoles
Cell Line, Tumor
Endoplasmic Reticulum
Fluorescent Dyes
fms-Like Tyrosine Kinase 3
Gene Expression Regulation, Neoplastic
Gene Knockdown Techniques
Glycogen Synthase Kinase 3
Glycogen Synthase Kinase 3 beta
Humans
Hydrogen Peroxide
Imidazoles
Leukemia, Myeloid, Acute
Mitochondria
Mutation
NADPH Oxidases
Proteasome Endopeptidase Complex
Protein Kinase Inhibitors
Protein Structure, Tertiary
Proto-Oncogene Proteins c-pim-1
Pyrroles
RNA, Small Interfering
Signal Transduction
STAT5 Transcription Factor
Staurosporine
Triazoles
authors with profiles
Bryan Dickinson