22807997Woolley JF, Naughton R, Stanicka J, Gough DR, Bhatt L, Dickinson BC, Chang CJ, Cotter TGPloS onefms-Like Tyrosine Kinase 3; Gene Expression Regulation, Neoplastic; Hydrogen Peroxide; Leukemia, Myeloid, Acute; NADPH Oxidases; STAT5 Transcription FactorBenzoxazoles; Cell Line, Tumor; Endoplasmic Reticulum; Fluorescent Dyes; Gene Knockdown Techniques; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Imidazoles; Mitochondria; Mutation; Proteasome Endopeptidase Complex; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-pim-1; Pyrroles; RNA, Small Interfering; Signal Transduction; Staurosporine; TriazolesH2O2 production downstream of FLT3 is mediated by p22phox in the endoplasmic reticulum and is required for STAT5 signalling. PLoS One. 2012; 7(7):e34050.PLoS One2012-07-13T00:00:002012H2O2 production downstream of FLT3 is mediated by p22phox in the endoplasmic reticulum and is required for STAT5 signalling.prns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD001583Chemicals & Drugs440.998327BenzoxazolesBryanDickinson02tqa6gbCuPXsW9naE/t8mL1sc65/A==Bryan Dickinson41.7886000000000087.598699999999993482Dickinson, BryanProfessor D007093Chemicals & Drugs1061630.909045ImidazolesD004721Anatomy1032500.866987Endoplasmic ReticulumD006861Chemicals & Drugs791570.932127Hydrogen PeroxideD009154Physiology70239520.442648MutationAuthorship 13663960.1110510.1110511authors10.2526has subject areaD006801Living Beings2262862810.130052HumansD008928AnatomyPhysiology2095350.748731MitochondriaD015470Disorders1227550.629242Leukemia, Myeloid, AcuteD017434Concepts & Ideas2687360.844002Protein Structure, TertiaryD019311Chemicals & Drugs24330.986039StaurosporineD051573Chemicals & Drugs9100.991865Proto-Oncogene Proteins c-pim-1D046988Chemicals & Drugs67990.951878Proteasome Endopeptidase ComplexD011758Chemicals & Drugs621840.890788PyrrolesD038362Chemicals & Drugs45630.962667Glycogen Synthase Kinase 3D014230Chemicals & Drugs60960.934372TriazolesD019255Chemicals & Drugs40810.940302NADPH OxidasesD055785Procedures1412340.920349Gene Knockdown TechniquesD050799Chemicals & Drugs25420.984797STAT5 Transcription FactorD034741Chemicals & Drugs2335470.850016RNA, Small InterferingD045744Anatomy46824210.643233Cell Line, TumorD051941Chemicals & Drugs431210.931518fms-Like Tyrosine Kinase 3D00007167930370.99106Glycogen Synthase Kinase 3 betaD005456Chemicals & Drugs1332420.876373Fluorescent DyesD015398Physiology69932330.460036Signal TransductionD015972Physiology31511960.666181Gene Expression Regulation, NeoplasticD047428Chemicals & Drugs2065890.714193Protein Kinase InhibitorsChemistryUniversity of Chicagotrue1Professor Professor