Resistance to thyroid hormone caused by two mutant thyroid hormone receptors beta, R243Q and R243W, with marked impairment of function that cannot be explained by altered in vitro 3,5,3'-triiodothyroinine binding affinity.

Resistance to thyroid hormone caused by two mutant thyroid hormone receptors beta, R243Q and R243W, with marked impairment of function that cannot be explained by altered in vitro 3,5,3'-triiodothyroinine binding affinity. J Clin Endocrinol Metab. 1997 May; 82(5):1608-14.

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subject areas

Animals
Cell Nucleus
DNA
Humans
Macromolecular Substances
Mutation
Pituitary Gland
Receptors, Thyroid Hormone
Thyroid Hormone Resistance Syndrome
Thyrotropin
Thyroxine
Transcriptional Activation
Transfection
Triiodothyronine
Tumor Cells, Cultured

authors with profiles

Samuel Refetoff