DemetArac-OzkanDemet Arac-Ozkan0.000000000000000.000000000000002885Arac-Ozkan, DemetBrainstructural biologyElectron MicroscopyCrystallography, X RaymulticellularityCell Surface ProteinsMembrane ProteinsG Protein Coupled ReceptorsSignaling PathwaysSynapsescortex developmentMyelinationNeurobiology, MolecularPI last name in publications: ARAÇ
ARAÇ LAB RESEARCH
Cells in multicellular organisms have the extraordinary ability of adhering to each other and exchanging information. Cellular adhesion and communication is essential for the development of all organs such as the brain, and is a key phenomenon that is disrupted in many human diseases. The Araç Lab is interested in understanding cellular communication with a special focus on the cell-surface receptors that mediate intercellular adhesion and communication. Genetic studies revealed critical roles for these surface proteins in embryonic development (especially of the brain and the heart), and in neurobiology (especially in synaptogenesis, axon pathfinding, axon-dendrite partner marching and wiring the brain); and link them to numerous diseases including neurological disorders, developmental impairments, multiple types of cancers (such as glioblastoma and ovarian cancer) and congenital general anosmia (the inability to smell). Considering that many drugs target the extracellular regions of membrane receptors to regulate receptor function, and have excellent therapeutic benefits, these proteins may be promising targets for drugs to treat numerous diseases once mechanistic details about the components that regulate their functions are understood. However, in spite of the recent exciting advances, their mechanisms of action, high-resolution structures in isolation or in complex with their ligands, and how they can mediate such broad range of functions remain majorly unknown. Our lab’s ultimate goal is to understand the mechanisms by which cell-adhesion receptors mediate communication between cells.Associate Professorplugins:TwitterTwitterprns:awardConferredByaward conferred byprns:coAuthorOfcoauthor ofprns:emailEncryptedemail addressprns:endDateend dateprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:trainingAtOrganizationeducational organizationprns:trainingLocationtraining locationprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipvivo:awardOrHonorawards and honorsAward or Honor Receiptvivo:degreeEarneddegree earnedDepartmentvivo:educationalTrainingeducation and trainingEducational Trainingvivo:freetextKeywordkeywordsGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:majorFieldmajor field of degreevivo:overviewoverviewvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson18093522Araç D, Boucard AA, Ozkan E, Strop P, Newell E, Südhof TC, Brunger ATNeuronStructures of neuroligin-1 and the neuroligin-1/neurexin-1 beta complex reveal specific protein-protein and protein-Ca2+ interactions. Neuron. 2007 Dec 20; 56(6):992-1003.Neuron2007-12-20T00:00:002007Structures of neuroligin-1 and the neuroligin-1/neurexin-1 beta complex reveal specific protein-protein and protein-Ca2+ interactions.Biochemistry and Molecular BiologyMolecular Genetics and Cell BiologyNeurobiologyAuthorship 10915313Authorship 10915413Authorship 1091556Authorship 10915613Authorship 1091577Authorship 1091582Authorship 1091592Authorship 1091604Authorship 1091618Authorship 1091623Authorship 1091631Authorship 1091646Authorship 1091652Authorship 1091663Authorship 10916710Authorship 1091686Authorship 1091694Authorship 1091703Authorship 1091717Authorship 1091729Authorship 1091736Authorship 1091749Authorship 1091756Authorship 1091763Authorship 1091773Authorship 1091783Authorship 1091795Authorship 1091805Authorship 1091817Authorship 1091824Authorship 109183Authorship 1091846Authorship 109185428874577Salzman GS, Zhang S, Gupta A, Koide A, Koide S, Araç DProceedings of the National Academy of Sciences of the United States of AmericaStachel-independent modulation of GPR56/ADGRG1 signaling by synthetic ligands directed to its extracellular region. Proc Natl Acad Sci U S A. 2017 09 19; 114(38):10095-10100.Proc Natl Acad Sci U S A2017-09-05T00:00:002017Stachel-independent modulation of GPR56/ADGRG1 signaling by synthetic ligands directed to its extracellular region.23850273Prömel S, Langenhan T, Araç DTrends in pharmacological sciencesMatching structure with function: the GAIN domain of adhesion-GPCR and PKD1-like proteins. Trends Pharmacol Sci. 2013 Aug; 34(8):470-8.Trends Pharmacol Sci2013-07-11T00:00:002013Matching structure with function: the GAIN domain of adhesion-GPCR and PKD1-like proteins.20471353Zhang C, Atasoy D, Araç D, Yang X, Fucillo MV, Robison AJ, Ko J, Brunger AT, Südhof TCNeuronNeurexins physically and functionally interact with GABA(A) receptors. Neuron. 2010 May 13; 66(3):403-16.Neuron2010-05-13T00:00:002010Neurexins physically and functionally interact with GABA(A) receptors.19730411Ko J, Zhang C, Arac D, Boucard AA, Brunger AT, Südhof TCThe EMBO journalNeuroligin-1 performs neurexin-dependent and neurexin-independent functions in synapse validation. EMBO J. 2009 Oct 21; 28(20):3244-55.EMBO J2009-09-03T00:00:002009Neuroligin-1 performs neurexin-dependent and neurexin-independent functions in synapse validation.16491093Araç D, Chen X, Khant HA, Ubach J, Ludtke SJ, Kikkawa M, Johnson AE, Chiu W, Südhof TC, Rizo JNature structural & molecular biologyClose membrane-membrane proximity induced by Ca(2+)-dependent multivalent binding of synaptotagmin-1 to phospholipids. Nat Struct Mol Biol. 2006 Mar; 13(3):209-17.Nat Struct Mol Biol2006-02-19T00:00:002006Close membrane-membrane proximity induced by Ca(2+)-dependent multivalent binding of synaptotagmin-1 to phospholipids.16361343Chen X, Araç D, Wang TM, Gilpin CJ, Zimmerberg J, Rizo JBiophysical journalSNARE-mediated lipid mixing depends on the physical state of the vesicles. Biophys J. 2006 Mar 15; 90(6):2062-74.Biophys J2005-12-16T00:00:002005SNARE-mediated lipid mixing depends on the physical state of the vesicles.15670607Araç D, Dulubova I, Pei J, Huryeva I, Grishin NV, Rizo JJournal of molecular biologyThree-dimensional structure of the rSly1 N-terminal domain reveals a conformational change induced by binding to syntaxin 5. J Mol Biol. 2005 Feb 18; 346(2):589-601.J Mol Biol2004-12-24T00:00:002004Three-dimensional structure of the rSly1 N-terminal domain reveals a conformational change induced by binding to syntaxin 5.11832227Chen X, Tomchick DR, Kovrigin E, Ara? D, Machius M, S?dhof TC, Rizo JNeuronThree-dimensional structure of the complexin/SNARE complex. Neuron. 2002 Jan 31; 33(3):397-409.Neuron2002-01-31T00:00:002002Three-dimensional structure of the complexin/SNARE complex.29765606Skubák P, Araç D, Bowler MW, Correia AR, Hoelz A, Larsen S, Leonard GA, McCarthy AA, McSweeney S, Mueller-Dieckmann C, Otten H, Salzman G, Pannu NSIUCrJA new MR-SAD algorithm for the automatic building of protein models from low-resolution X-ray data and a poor starting model. IUCrJ. 2018 Mar 01; 5(Pt 2):166-171.IUCrJ2018-01-25T00:00:002018A new MR-SAD algorithm for the automatic building of protein models from low-resolution X-ray data and a poor starting model.23215895Araç D, Aust G, Calebiro D, Engel FB, Formstone C, Goffinet A, Hamann J, Kittel RJ, Liebscher I, Lin HH, Monk KR, Petrenko A, Piao X, Prömel S, Schiöth HB, Schwartz TW, Stacey M, Ushkaryov YA, Wobus M, Wolfrum U, Xu L, Langenhan TAnnals of the New York Academy of SciencesDissecting signaling and functions of adhesion G protein-coupled receptors. Ann N Y Acad Sci. 2012 Dec; 1276:1-25.Ann N Y Acad Sci2012-12-07T00:00:002012Dissecting signaling and functions of adhesion G protein-coupled receptors.16595652Li L, Shin OH, Rhee JS, Araç D, Rah JC, Rizo J, Südhof T, Rosenmund CThe Journal of biological chemistryPhosphatidylinositol phosphates as co-activators of Ca2+ binding to C2 domains of synaptotagmin 1. J Biol Chem. 2006 Jun 09; 281(23):15845-52.J Biol Chem2006-04-04T00:00:002006Phosphatidylinositol phosphates as co-activators of Ca2+ binding to C2 domains of synaptotagmin 1.12460570Kulik V, Weyand M, Seidel R, Niks D, Arac D, Dunn MF, Schlichting IJournal of molecular biologyOn the role of alphaThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase. J Mol Biol. 2002 Dec 06; 324(4):677-90.J Mol Biol2002-12-06T00:00:002002On the role of alphaThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase.12114520Antonin W, Dulubova I, Arac D, Pabst S, Plitzner J, Rizo J, Jahn RThe Journal of biological chemistryThe N-terminal domains of syntaxin 7 and vti1b form three-helix bundles that differ in their ability to regulate SNARE complex assembly. J Biol Chem. 2002 Sep 27; 277(39):36449-56.J Biol Chem2002-07-11T00:00:002002The N-terminal domains of syntaxin 7 and vti1b form three-helix bundles that differ in their ability to regulate SNARE complex assembly.26235030Lu YC, Nazarko OV, Sando R, Salzman GS, Li NS, Südhof TC, Araç DStructure (London, England : 1993)Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion. Structure. 2015 Sep 01; 23(9):1678-1691.Structure2015-07-30T00:00:002015Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion.25713288Hamann J, Aust G, Araç D, Engel FB, Formstone C, Fredriksson R, Hall RA, Harty BL, Kirchhoff C, Knapp B, Krishnan A, Liebscher I, Lin HH, Martinelli DC, Monk KR, Peeters MC, Piao X, Prömel S, Schöneberg T, Schwartz TW, Singer K, Stacey M, Ushkaryov YA, Vallon M, Wolfrum U, Wright MW, Xu L, Langenhan T, Schiöth HBPharmacological reviewsInternational Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors. Pharmacol Rev. 2015; 67(2):338-67.Pharmacol Rev2015-01-01T00:00:002015International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.25424900Liebscher I, Ackley B, Araç D, Ariestanti DM, Aust G, Bae BI, Bista BR, Bridges JP, Duman JG, Engel FB, Giera S, Goffinet AM, Hall RA, Hamann J, Hartmann N, Lin HH, Liu M, Luo R, Mogha A, Monk KR, Peeters MC, Prömel S, Ressl S, Schiöth HB, Sigoillot SM, Song H, Talbot WS, Tall GG, White JP, Wolfrum U, Xu L, Piao XAnnals of the New York Academy of SciencesNew functions and signaling mechanisms for the class of adhesion G protein-coupled receptors. Ann N Y Acad Sci. 2014 Dec; 1333:43-64.Ann N Y Acad Sci2014-11-25T00:00:002014New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors.25378172Tsetsenis T, Boucard AA, Araç D, Brunger AT, Südhof TCThe Journal of neuroscience : the official journal of the Society for NeuroscienceDirect visualization of trans-synaptic neurexin-neuroligin interactions during synapse formation. J Neurosci. 2014 Nov 05; 34(45):15083-96.J Neurosci2014-11-05T00:00:002014Direct visualization of trans-synaptic neurexin-neuroligin interactions during synapse formation.22333914Araç D, Boucard AA, Bolliger MF, Nguyen J, Soltis SM, Südhof TC, Brunger ATThe EMBO journalA novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis. EMBO J. 2012 Mar 21; 31(6):1364-78.EMBO J2012-02-14T00:00:002012A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis.17320903Dai H, Shen N, Araç D, Rizo JJournal of molecular biologyA quaternary SNARE-synaptotagmin-Ca2+-phospholipid complex in neurotransmitter release. J Mol Biol. 2007 Mar 30; 367(3):848-63.J Mol Biol2007-01-23T00:00:002007A quaternary SNARE-synaptotagmin-Ca2+-phospholipid complex in neurotransmitter release.12795692Jarousse N, Wilson JD, Arac D, Rizo J, Kelly RBTraffic (Copenhagen, Denmark)Endocytosis of synaptotagmin 1 is mediated by a novel, tryptophan-containing motif. Traffic. 2003 Jul; 4(7):468-78.Traffic2003-07-01T00:00:002003Endocytosis of synaptotagmin 1 is mediated by a novel, tryptophan-containing motif.12506202Dulubova I, Yamaguchi T, Arac D, Li H, Huryeva I, Min SW, Rizo J, Sudhof TCProceedings of the National Academy of Sciences of the United States of AmericaConvergence and divergence in the mechanism of SNARE binding by Sec1/Munc18-like proteins. Proc Natl Acad Sci U S A. 2003 Jan 07; 100(1):32-7.Proc Natl Acad Sci U S A2002-12-27T00:00:002002Convergence and divergence in the mechanism of SNARE binding by Sec1/Munc18-like proteins.12152619Hafezparast M, Ball S, Nicholson SJ, Witherden A, Arac D, Broadway N, Saggerson D, Cooper E, Naase M, Gokhale S, Quant P, Lascelles C, Nickols C, Baker CS, Peters J, Martin JE, Fisher EMMammalian genome : official journal of the International Mammalian Genome SocietyA new mouse mutant, skijumper. Mamm Genome. 2002 Jul; 13(7):359-364.Mamm Genome2002-07-01T00:00:002002A new mouse mutant, skijumper.11867214Witherden AS, Hafezparast M, Nicholson SJ, Ahmad-Annuar A, Bermingham N, Arac D, Rankin J, Iravani M, Ball S, Peters J, Martin JE, Huntley D, Hummerich H, Sergot M, Fisher EMGeneAn integrated genetic, radiation hybrid, physical and transcription map of a region of distal mouse chromosome 12, including an imprinted locus and the 'Legs at odd angles' (Loa) mutation. Gene. 2002 Jan 23; 283(1-2):71-82.Gene2002-01-23T00:00:002002An integrated genetic, radiation hybrid, physical and transcription map of a region of distal mouse chromosome 12, including an imprinted locus and the 'Legs at odd angles' (Loa) mutation.11754837Fernandez I, Araç D, Ubach J, Gerber SH, Shin O, Gao Y, Anderson RG, Südhof TC, Rizo JNeuronThree-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine. Neuron. 2001 Dec 20; 32(6):1057-69.Neuron2001-12-20T00:00:002001Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine.29677516Li J, Shalev-Benami M, Sando R, Jiang X, Kibrom A, Wang J, Leon K, Katanski C, Nazarko O, Lu YC, Südhof TC, Skiniotis G, Araç DCellStructural Basis for Teneurin Function in Circuit-Wiring: A Toxin Motif at the Synapse. Cell. 2018 04 19; 173(3):735-748.e15.Cell2018-04-19T00:00:002018Structural Basis for Teneurin Function in Circuit-Wiring: A Toxin Motif at the Synapse.24949629Luo R, Jeong SJ, Yang A, Wen M, Saslowsky DE, Lencer WI, Araç D, Piao XPloS oneMechanism for adhesion G protein-coupled receptor GPR56-mediated RhoA activation induced by collagen III stimulation. PLoS One. 2014; 9(6):e100043.PLoS One2014-06-20T00:00:002014Mechanism for adhesion G protein-coupled receptor GPR56-mediated RhoA activation induced by collagen III stimulation.18940613Zuniga JE, Schmidt JJ, Fenn T, Burnett JC, Araç D, Gussio R, Stafford RG, Badie SS, Bavari S, Brunger ATStructure (London, England : 1993)A potent peptidomimetic inhibitor of botulinum neurotoxin serotype A has a very different conformation than SNAP-25 substrate. Structure. 2008 Oct 08; 16(10):1588-97.Structure2008-10-08T00:00:002008A potent peptidomimetic inhibitor of botulinum neurotoxin serotype A has a very different conformation than SNAP-25 substrate.16698267Rizo J, Chen X, Araç DTrends in cell biologyUnraveling the mechanisms of synaptotagmin and SNARE function in neurotransmitter release. Trends Cell Biol. 2006 Jul; 16(7):339-50.Trends Cell Biol2006-05-12T00:00:002006Unraveling the mechanisms of synaptotagmin and SNARE function in neurotransmitter release.16319061Ferguson AD, Labunskyy VM, Fomenko DE, Araç D, Chelliah Y, Amezcua CA, Rizo J, Gladyshev VN, Deisenhofer JThe Journal of biological chemistryNMR structures of the selenoproteins Sep15 and SelM reveal redox activity of a new thioredoxin-like family. J Biol Chem. 2006 Feb 10; 281(6):3536-43.J Biol Chem2005-11-30T00:00:002005NMR structures of the selenoproteins Sep15 and SelM reveal redox activity of a new thioredoxin-like family.12627942Araç D, Murphy T, Rizo JBiochemistryFacile detection of protein-protein interactions by one-dimensional NMR spectroscopy. Biochemistry. 2003 Mar 18; 42(10):2774-80.Biochemistry2003-03-18T00:00:002003Facile detection of protein-protein interactions by one-dimensional NMR spectroscopy.11352720Ubach J, Lao Y, Fernandez I, Arac D, Südhof TC, Rizo JBiochemistryThe C2B domain of synaptotagmin I is a Ca2+-binding module. Biochemistry. 2001 May 22; 40(20):5854-60.Biochemistry2001-05-22T00:00:002001The C2B domain of synaptotagmin I is a Ca2+-binding module.2013Stanford UniversityStanford, CAStanford University, Structural and Cellular BiologyPostdoctoralStructural and Cellular Biology2006UT Southwestern Med. CenterDallas, TXUT Southwestern Med. Center, Molecular BiophysicsPhDMolecular Biophysics1999Bilkent UniversityAnkara, Turkey Bilkent University, Molecular Biology and GeneticsBSMolecular Biology and GeneticsHoward Hughes Medical Center20102007Life Sciences Research Foundation Postdoctoral FellowshipBrain Research Foundation 20152014Fay/Frank Seed GrantUniversity of Chicago20152014Big Ideas Generator University of California, Riverside20001999Chancellor’s Distinguished FellowshipAuthorship 1260021230428326Nazarko O, Kibrom A, Winkler J, Leon K, Stoveken H, Salzman G, Merdas K, Lu Y, Narkhede P, Tall G, Prömel S, Araç DiScienceA Comprehensive Mutagenesis Screen of the Adhesion GPCR Latrophilin-1/ADGRL1. iScience. 2018 May 25; 3:264-278.iScience2018-04-30T00:00:002018A Comprehensive Mutagenesis Screen of the Adhesion GPCR Latrophilin-1/ADGRL1.Authorship 128885230952063Araç D, Li JCurrent opinion in structural biologyTeneurins and latrophilins: two giants meet at the synapse. Curr Opin Struct Biol. 2019 02; 54:141-151.Curr Opin Struct Biol2019-04-02T00:00:002019Teneurins and latrophilins: two giants meet at the synapse.D008565Chemicals & Drugs37111940.607129Membrane ProteinsD009419Chemicals & Drugs2005030.780094Nerve Tissue ProteinsD013569Anatomy812650.826498SynapsesChicago60637ILEnginOzkanEngin Ozkan0.000000000000000.000000000000002877Ozkan, EnginAssociate Professor4.194480.00852865226research areas0.1371420.02023362coauthor of20.91524.60660similar to1136selected publicationsD043562Chemicals & Drugs761140.911264Receptors, G-Protein-CoupledD059748Physiology731000.942264ProteolysisChuanHe1Gp8Cq8dHMzMknJtY0fp/Cv/+94=Chuan He0.000000000000000.000000000000003123He, ChuanProfessorhttp://feilab.uchicago.edu/Fei Grouphttps://neuroscience.uchicago.edu/Neuroscience Institutehttps://voices.uchicago.edu/ozkanlabThe Özkan Lab at the University of Chicagohttp://bmb.uchospitals.edu/Department of Biochemistry and Molecular Biologyhttp://arac.uchicago.eduArac Labhttp://voices.uchicago.edu/drsisodialab/Sisodia Labhttp://he-group.uchicago.eduMy Lab Sitehttps://voices.uchicago.edu/fehonlab/Fehon Labhttp://kosslab.uchicago.eduKosslabhttps://zhaolab.uchicago.eduZhao Labhttps://arac.uchicago.edu/page/publicationsArac Lab Publicationshttp://recombinant-antibodies.orgRecombinant Antibody Network@demet_arachttps://twitter.com/fei_jingyi2021-05-31NIHARAC-OZKAN, DEMET2016-09-15Structural and Functional Studies of Adhesion GPCRsR01GM1203222023-08-31NIHARAC-OZKAN, DEMET2019-09-01Structural and Functional Studies of Teneurins: A bacterial toxin homolog in humanR01GM1340352020-08-31NIHARAC-OZKAN, DEMET2019-09-01Structural and Functional Studies of Brain Angiogenesis Inhibitors (BAIs/ADGRBs)R03MH122261Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorChemistryMedicinePathologyUniversity of ChicagoAnthonyKossiakoff1mlmGLIcGOf5hHlsaUXv9Gq0+s+oAnthony Kossiakoff41.78927490000000-87.601250000000001188Kossiakoff, AnthonyProfessorRichard G.FehonRichard G. Fehon41.78927490000000-87.601250000000001759Fehon, Richard G.ProfessorNan-ShengLiNan-Sheng Li41.78927490000000-87.60125000000000351Li, Nan-ShengSangram S.SisodiaxHF6ArIaHeX5hHlsaUXv9Gq0+s+oSangram S. Sisodia41.78927490000000-87.60125000000000510Sisodia, Sangram S.ProfessorYusukeNakamuraYusuke Nakamura41.78927490000000-87.60125000000000582Nakamura, YusukeEmeritus/Emerita, Professortrue1true1true1Associate ProfessorAssociate Professortrue1Assistant ProfessorAssistant Professortrue1Associate ProfessorAssociate Professortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1Emeritus/Emerita, ProfessorEmeritus/Emerita, Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate ProfessorGeoffreyWoolGeoffrey Wool0.000000000000000.000000000000003213Wool, GeoffreyAssociate ProfessorJingyiFeiJingyi Fei0.000000000000000.000000000000003274Fei, JingyiAssistant Professor27657451Salzman GS, Ackerman SD, Ding C, Koide A, Leon K, Luo R, Stoveken HM, Fernandez CG, Tall GG, Piao X, Monk KR, Koide S, Araç DNeuronStructural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains. Neuron. 2016 Sep 21; 91(6):1292-1304.Neuron2016-09-21T00:00:002016Structural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains.SatoeHommaSatoe Homma0.000000000000000.000000000000002846Homma, SatoeAuthorship 97135227832484Araç D, Sträter N, Seiradake EHandbook of experimental pharmacologyUnderstanding the Structural Basis of Adhesion GPCR Functions. Handb Exp Pharmacol. 2016; 234:67-82.Handb Exp Pharmacol2016-01-01T00:00:002016Understanding the Structural Basis of Adhesion GPCR Functions.MingleiZhaoMinglei Zhao0.000000000000000.000000000000003410Zhao, MingleiAssociate Professor