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Connection

Gokhan M. Mutlu to Animals

This is a "connection" page, showing publications Gokhan M. Mutlu has written about Animals.
Connection Strength

1.993
  1. The role of metabolic reprogramming and de novo amino acid synthesis in collagen protein production by myofibroblasts: implications for organ fibrosis and cancer. Amino Acids. 2021 Dec; 53(12):1851-1862.
    View in: PubMed
    Score: 0.051
  2. The lung microenvironment shapes a dysfunctional response of alveolar macrophages in aging. J Clin Invest. 2021 02 15; 131(4).
    View in: PubMed
    Score: 0.050
  3. Metabolic requirements of pulmonary fibrosis: role of fibroblast metabolism. FEBS J. 2021 11; 288(22):6331-6352.
    View in: PubMed
    Score: 0.050
  4. Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response. Elife. 2020 04 07; 9.
    View in: PubMed
    Score: 0.047
  5. Tissue-Resident Alveolar Macrophages Do Not Rely on Glycolysis for LPS-induced Inflammation. Am J Respir Cell Mol Biol. 2020 02; 62(2):243-255.
    View in: PubMed
    Score: 0.047
  6. Suppression of Superoxide-Hydrogen Peroxide Production at Site IQ of Mitochondrial Complex I Attenuates Myocardial Stunning and Improves Postcardiac Arrest Outcomes. Crit Care Med. 2020 02; 48(2):e133-e140.
    View in: PubMed
    Score: 0.047
  7. Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis. Am J Respir Crit Care Med. 2019 06 15; 199(12):1517-1536.
    View in: PubMed
    Score: 0.045
  8. Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis. Cell Metab. 2019 02 05; 29(2):335-347.e5.
    View in: PubMed
    Score: 0.042
  9. Inhalational exposure to particulate matter air pollution alters the composition of the gut microbiome. Environ Pollut. 2018 Sep; 240:817-830.
    View in: PubMed
    Score: 0.041
  10. Inhibition of Phosphoglycerate Dehydrogenase Attenuates Bleomycin-induced Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2018 05; 58(5):585-593.
    View in: PubMed
    Score: 0.041
  11. Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span. J Exp Med. 2017 Aug 07; 214(8):2387-2404.
    View in: PubMed
    Score: 0.039
  12. HIF-1a is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium. Elife. 2017 05 30; 6.
    View in: PubMed
    Score: 0.039
  13. Experimental Lung Injury Reduces Krüppel-like Factor 2 to Increase Endothelial Permeability via Regulation of RAPGEF3-Rac1 Signaling. Am J Respir Crit Care Med. 2017 03 01; 195(5):639-651.
    View in: PubMed
    Score: 0.038
  14. Prolonged Exposures to Intermittent Hypoxia Promote Visceral White Adipose Tissue Inflammation in a Murine Model of Severe Sleep Apnea: Effect of Normoxic Recovery. Sleep. 2017 03 01; 40(3).
    View in: PubMed
    Score: 0.038
  15. SIRT3 blocks myofibroblast differentiation and pulmonary fibrosis by preventing mitochondrial DNA damage. Am J Physiol Lung Cell Mol Physiol. 2017 01 01; 312(1):L68-L78.
    View in: PubMed
    Score: 0.037
  16. Macrophage-epithelial paracrine crosstalk inhibits lung edema clearance during influenza infection. J Clin Invest. 2016 Apr 01; 126(4):1566-80.
    View in: PubMed
    Score: 0.036
  17. Regulation of allergic lung inflammation by endothelial cell transglutaminase 2. Am J Physiol Lung Cell Mol Physiol. 2015 Sep 15; 309(6):L573-83.
    View in: PubMed
    Score: 0.034
  18. Nitric oxide prevents alveolar senescence and emphysema in a mouse model. PLoS One. 2015; 10(3):e0116504.
    View in: PubMed
    Score: 0.033
  19. Asbestos-induced pulmonary fibrosis is augmented in 8-oxoguanine DNA glycosylase knockout mice. Am J Respir Cell Mol Biol. 2015 Jan; 52(1):25-36.
    View in: PubMed
    Score: 0.033
  20. Nonclassical Ly6C(-) monocytes drive the development of inflammatory arthritis in mice. Cell Rep. 2014 Oct 23; 9(2):591-604.
    View in: PubMed
    Score: 0.032
  21. Impaired clearance of influenza A virus in obese, leptin receptor deficient mice is independent of leptin signaling in the lung epithelium and macrophages. PLoS One. 2014; 9(9):e108138.
    View in: PubMed
    Score: 0.032
  22. Intratracheal administration of influenza virus is superior to intranasal administration as a model of acute lung injury. J Virol Methods. 2014 Dec; 209:116-20.
    View in: PubMed
    Score: 0.032
  23. Wnt coreceptor Lrp5 is a driver of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2014 Jul 15; 190(2):185-95.
    View in: PubMed
    Score: 0.032
  24. ß2-Adrenergic agonists augment air pollution-induced IL-6 release and thrombosis. J Clin Invest. 2014 Jul; 124(7):2935-46.
    View in: PubMed
    Score: 0.031
  25. Loss of TLR4 does not prevent influenza A-induced mortality. Am J Respir Crit Care Med. 2014 May 15; 189(10):1280-1.
    View in: PubMed
    Score: 0.031
  26. PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice. Proc Natl Acad Sci U S A. 2014 May 13; 111(19):7090-5.
    View in: PubMed
    Score: 0.031
  27. Flow cytometric analysis of macrophages and dendritic cell subsets in the mouse lung. Am J Respir Cell Mol Biol. 2013 Oct; 49(4):503-10.
    View in: PubMed
    Score: 0.030
  28. Sequestration of mitochondrial iron by silica particle initiates a biological effect. Am J Physiol Lung Cell Mol Physiol. 2013 Nov 15; 305(10):L712-24.
    View in: PubMed
    Score: 0.030
  29. Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-d. Nat Immunol. 2013 May; 14(5):461-9.
    View in: PubMed
    Score: 0.029
  30. Toll-like receptor 4 signaling augments transforming growth factor-ß responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma. Am J Pathol. 2013 Jan; 182(1):192-205.
    View in: PubMed
    Score: 0.028
  31. Inhibition of allergic inflammation by supplementation with 5-hydroxytryptophan. Am J Physiol Lung Cell Mol Physiol. 2012 Oct 15; 303(8):L642-60.
    View in: PubMed
    Score: 0.028
  32. The effect of rosuvastatin in a murine model of influenza A infection. PLoS One. 2012; 7(4):e35788.
    View in: PubMed
    Score: 0.027
  33. Alcohol worsens acute lung injury by inhibiting alveolar sodium transport through the adenosine A1 receptor. PLoS One. 2012; 7(1):e30448.
    View in: PubMed
    Score: 0.027
  34. Minimizing oxidation and stable nanoscale dispersion improves the biocompatibility of graphene in the lung. Nano Lett. 2011 Dec 14; 11(12):5201-7.
    View in: PubMed
    Score: 0.026
  35. Proteasomal inhibition after injury prevents fibrosis by modulating TGF-ß(1) signalling. Thorax. 2012 Feb; 67(2):139-46.
    View in: PubMed
    Score: 0.026
  36. Linking air pollution exposure with thrombosis. Blood. 2011 Sep 01; 118(9):2636-7.
    View in: PubMed
    Score: 0.026
  37. Hypoxia leads to Na,K-ATPase downregulation via Ca(2+) release-activated Ca(2+) channels and AMPK activation. Mol Cell Biol. 2011 Sep; 31(17):3546-56.
    View in: PubMed
    Score: 0.026
  38. Particulate matter air pollution causes oxidant-mediated increase in gut permeability in mice. Part Fibre Toxicol. 2011 Jun 09; 8:19.
    View in: PubMed
    Score: 0.026
  39. Particulate matter-induced lung inflammation increases systemic levels of PAI-1 and activates coagulation through distinct mechanisms. PLoS One. 2011 Apr 11; 6(4):e18525.
    View in: PubMed
    Score: 0.025
  40. Leptin promotes fibroproliferative acute respiratory distress syndrome by inhibiting peroxisome proliferator-activated receptor-?. Am J Respir Crit Care Med. 2011 Jun 01; 183(11):1490-8.
    View in: PubMed
    Score: 0.025
  41. Epithelial cell death is an important contributor to oxidant-mediated acute lung injury. Am J Respir Crit Care Med. 2011 Apr 15; 183(8):1043-54.
    View in: PubMed
    Score: 0.024
  42. Update in environmental and occupational medicine 2009. Am J Respir Crit Care Med. 2010 Jun 01; 181(11):1174-80.
    View in: PubMed
    Score: 0.024
  43. Biocompatible nanoscale dispersion of single-walled carbon nanotubes minimizes in vivo pulmonary toxicity. Nano Lett. 2010 May 12; 10(5):1664-70.
    View in: PubMed
    Score: 0.024
  44. Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity. Proc Natl Acad Sci U S A. 2010 May 11; 107(19):8788-93.
    View in: PubMed
    Score: 0.024
  45. Proteasomal regulation of pulmonary fibrosis. Proc Am Thorac Soc. 2010 Feb; 7(1):77-83.
    View in: PubMed
    Score: 0.023
  46. Beta-catenin/T-cell factor signaling is activated during lung injury and promotes the survival and migration of alveolar epithelial cells. J Biol Chem. 2010 Jan 29; 285(5):3157-67.
    View in: PubMed
    Score: 0.023
  47. Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio. Free Radic Biol Med. 2009 May 15; 46(10):1386-91.
    View in: PubMed
    Score: 0.022
  48. Proapoptotic Noxa is required for particulate matter-induced cell death and lung inflammation. FASEB J. 2009 Jul; 23(7):2055-64.
    View in: PubMed
    Score: 0.022
  49. Mitochondrial complex III-generated oxidants activate ASK1 and JNK to induce alveolar epithelial cell death following exposure to particulate matter air pollution. J Biol Chem. 2009 Jan 23; 284(4):2176-86.
    View in: PubMed
    Score: 0.021
  50. Stretch-induced activation of AMP kinase in the lung requires dystroglycan. Am J Respir Cell Mol Biol. 2008 Dec; 39(6):666-72.
    View in: PubMed
    Score: 0.021
  51. Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway. J Clin Invest. 2007 Oct; 117(10):2952-61.
    View in: PubMed
    Score: 0.020
  52. Alveolar epithelial beta2-adrenergic receptors. Am J Respir Cell Mol Biol. 2008 Feb; 38(2):127-34.
    View in: PubMed
    Score: 0.020
  53. The intrinsic apoptotic pathway is required for lipopolysaccharide-induced lung endothelial cell death. J Immunol. 2007 Aug 01; 179(3):1834-41.
    View in: PubMed
    Score: 0.020
  54. Electroporation-mediated gene transfer of the Na+,K+ -ATPase rescues endotoxin-induced lung injury. Am J Respir Crit Care Med. 2007 Sep 15; 176(6):582-90.
    View in: PubMed
    Score: 0.019
  55. Adenosine regulation of alveolar fluid clearance. Proc Natl Acad Sci U S A. 2007 Mar 06; 104(10):4083-8.
    View in: PubMed
    Score: 0.019
  56. Leptin resistance protects mice from hyperoxia-induced acute lung injury. Am J Respir Crit Care Med. 2007 Mar 15; 175(6):587-94.
    View in: PubMed
    Score: 0.019
  57. p53 mediates particulate matter-induced alveolar epithelial cell mitochondria-regulated apoptosis. Am J Respir Crit Care Med. 2006 Dec 01; 174(11):1229-38.
    View in: PubMed
    Score: 0.018
  58. Air pollution impairs lung's ability to clear edema fluid. Am J Cardiol. 2006 Aug 01; 98(3):423-4.
    View in: PubMed
    Score: 0.018
  59. Proapoptotic Bid is required for pulmonary fibrosis. Proc Natl Acad Sci U S A. 2006 Mar 21; 103(12):4604-9.
    View in: PubMed
    Score: 0.018
  60. Airborne particulate matter inhibits alveolar fluid reabsorption in mice via oxidant generation. Am J Respir Cell Mol Biol. 2006 Jun; 34(6):670-6.
    View in: PubMed
    Score: 0.018
  61. Mechanisms of pulmonary edema clearance. Am J Physiol Lung Cell Mol Physiol. 2005 Nov; 289(5):L685-95.
    View in: PubMed
    Score: 0.017
  62. Interdependency of beta-adrenergic receptors and CFTR in regulation of alveolar active Na+ transport. Circ Res. 2005 May 13; 96(9):999-1005.
    View in: PubMed
    Score: 0.017
  63. Potential genetic therapies for acute lung injury. Curr Gene Ther. 2004 Dec; 4(4):487-95.
    View in: PubMed
    Score: 0.016
  64. beta(2)-Agonists for treatment of pulmonary edema: ready for clinical studies? Crit Care Med. 2004 Jul; 32(7):1607-8.
    View in: PubMed
    Score: 0.016
  65. Upregulation of alveolar epithelial active Na+ transport is dependent on beta2-adrenergic receptor signaling. Circ Res. 2004 Apr 30; 94(8):1091-100.
    View in: PubMed
    Score: 0.015
  66. Effects of beta2-adrenergic receptor overexpression on alveolar epithelial active transport. J Allergy Clin Immunol. 2002 Dec; 110(6 Suppl):S242-6.
    View in: PubMed
    Score: 0.014
  67. Comparison of surfactant and perfluorochemical liquid enhanced adenovirus-mediated gene transfer in normal rat lung. Mol Ther. 2002 Jul; 6(1):43-9.
    View in: PubMed
    Score: 0.014
  68. Acute lung injury does not impair adenoviral-mediated gene transfer to the alveolar epithelium. Chest. 2002 Mar; 121(3 Suppl):33S-34S.
    View in: PubMed
    Score: 0.013
  69. Enhancement of alveolar epithelial beta(2)-adrenergic receptor function via gene transfer. Chest. 2002 Mar; 121(3 Suppl):45S-46S.
    View in: PubMed
    Score: 0.013
  70. P311 Promotes Lung Fibrosis via Stimulation of Transforming Growth Factor-ß1, -ß2, and -ß3 Translation. Am J Respir Cell Mol Biol. 2019 02; 60(2):221-231.
    View in: PubMed
    Score: 0.011
  71. Influenza A Virus Infection Induces Muscle Wasting via IL-6 Regulation of the E3 Ubiquitin Ligase Atrogin-1. J Immunol. 2019 01 15; 202(2):484-493.
    View in: PubMed
    Score: 0.011
  72. Lung-specific loss of a3 laminin worsens bleomycin-induced pulmonary fibrosis. Am J Respir Cell Mol Biol. 2015 Apr; 52(4):503-12.
    View in: PubMed
    Score: 0.008
  73. Oxidized phospholipids protect against lung injury and endothelial barrier dysfunction caused by heat-inactivated Staphylococcus aureus. Am J Physiol Lung Cell Mol Physiol. 2015 Mar 15; 308(6):L550-62.
    View in: PubMed
    Score: 0.008
  74. Lung-specific loss of the laminin a3 subunit confers resistance to mechanical injury. J Cell Sci. 2011 Sep 01; 124(Pt 17):2927-37.
    View in: PubMed
    Score: 0.006
  75. Effects of body temperature on ventilator-induced lung injury. J Crit Care. 2005 Mar; 20(1):66-73.
    View in: PubMed
    Score: 0.004
  76. Acute hyperoxic lung injury does not impede adenoviral-mediated alveolar gene transfer. Am J Respir Crit Care Med. 2002 Feb 15; 165(4):521-6.
    View in: PubMed
    Score: 0.003
  77. beta(2)-adrenergic receptor overexpression increases alveolar fluid clearance and responsiveness to endogenous catecholamines in rats. Circ Res. 2001 Nov 09; 89(10):907-14.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.