Gokhan M. Mutlu to Animals
This is a "connection" page, showing publications Gokhan M. Mutlu has written about Animals.
Connection Strength
1.891
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The role of metabolic reprogramming and de novo amino acid synthesis in collagen protein production by myofibroblasts: implications for organ fibrosis and cancer. Amino Acids. 2021 Dec; 53(12):1851-1862.
Score: 0.048
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The lung microenvironment shapes a dysfunctional response of alveolar macrophages in aging. J Clin Invest. 2021 02 15; 131(4).
Score: 0.047
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Metabolic requirements of pulmonary fibrosis: role of fibroblast metabolism. FEBS J. 2021 11; 288(22):6331-6352.
Score: 0.047
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Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response. Elife. 2020 04 07; 9.
Score: 0.045
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Tissue-Resident Alveolar Macrophages Do Not Rely on Glycolysis for LPS-induced Inflammation. Am J Respir Cell Mol Biol. 2020 02; 62(2):243-255.
Score: 0.044
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Suppression of Superoxide-Hydrogen Peroxide Production at Site IQ of Mitochondrial Complex I Attenuates Myocardial Stunning and Improves Postcardiac Arrest Outcomes. Crit Care Med. 2020 02; 48(2):e133-e140.
Score: 0.044
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Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis. Am J Respir Crit Care Med. 2019 06 15; 199(12):1517-1536.
Score: 0.042
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Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis. Cell Metab. 2019 02 05; 29(2):335-347.e5.
Score: 0.040
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Inhalational exposure to particulate matter air pollution alters the composition of the gut microbiome. Environ Pollut. 2018 Sep; 240:817-830.
Score: 0.039
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Inhibition of Phosphoglycerate Dehydrogenase Attenuates Bleomycin-induced Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2018 05; 58(5):585-593.
Score: 0.039
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Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span. J Exp Med. 2017 Aug 07; 214(8):2387-2404.
Score: 0.037
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HIF-1a is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium. Elife. 2017 05 30; 6.
Score: 0.037
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Experimental Lung Injury Reduces Krüppel-like Factor 2 to Increase Endothelial Permeability via Regulation of RAPGEF3-Rac1 Signaling. Am J Respir Crit Care Med. 2017 03 01; 195(5):639-651.
Score: 0.036
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Prolonged Exposures to Intermittent Hypoxia Promote Visceral White Adipose Tissue Inflammation in a Murine Model of Severe Sleep Apnea: Effect of Normoxic Recovery. Sleep. 2017 03 01; 40(3).
Score: 0.036
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SIRT3 blocks myofibroblast differentiation and pulmonary fibrosis by preventing mitochondrial DNA damage. Am J Physiol Lung Cell Mol Physiol. 2017 01 01; 312(1):L68-L78.
Score: 0.035
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Macrophage-epithelial paracrine crosstalk inhibits lung edema clearance during influenza infection. J Clin Invest. 2016 Apr 01; 126(4):1566-80.
Score: 0.034
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Regulation of allergic lung inflammation by endothelial cell transglutaminase 2. Am J Physiol Lung Cell Mol Physiol. 2015 Sep 15; 309(6):L573-83.
Score: 0.032
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Nitric oxide prevents alveolar senescence and emphysema in a mouse model. PLoS One. 2015; 10(3):e0116504.
Score: 0.031
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Asbestos-induced pulmonary fibrosis is augmented in 8-oxoguanine DNA glycosylase knockout mice. Am J Respir Cell Mol Biol. 2015 Jan; 52(1):25-36.
Score: 0.031
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Nonclassical Ly6C(-) monocytes drive the development of inflammatory arthritis in mice. Cell Rep. 2014 Oct 23; 9(2):591-604.
Score: 0.031
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Impaired clearance of influenza A virus in obese, leptin receptor deficient mice is independent of leptin signaling in the lung epithelium and macrophages. PLoS One. 2014; 9(9):e108138.
Score: 0.030
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Intratracheal administration of influenza virus is superior to intranasal administration as a model of acute lung injury. J Virol Methods. 2014 Dec; 209:116-20.
Score: 0.030
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Wnt coreceptor Lrp5 is a driver of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2014 Jul 15; 190(2):185-95.
Score: 0.030
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ß2-Adrenergic agonists augment air pollution-induced IL-6 release and thrombosis. J Clin Invest. 2014 Jul; 124(7):2935-46.
Score: 0.030
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Loss of TLR4 does not prevent influenza A-induced mortality. Am J Respir Crit Care Med. 2014 May 15; 189(10):1280-1.
Score: 0.030
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PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice. Proc Natl Acad Sci U S A. 2014 May 13; 111(19):7090-5.
Score: 0.030
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Flow cytometric analysis of macrophages and dendritic cell subsets in the mouse lung. Am J Respir Cell Mol Biol. 2013 Oct; 49(4):503-10.
Score: 0.028
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Sequestration of mitochondrial iron by silica particle initiates a biological effect. Am J Physiol Lung Cell Mol Physiol. 2013 Nov 15; 305(10):L712-24.
Score: 0.028
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Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-d. Nat Immunol. 2013 May; 14(5):461-9.
Score: 0.027
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Toll-like receptor 4 signaling augments transforming growth factor-ß responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma. Am J Pathol. 2013 Jan; 182(1):192-205.
Score: 0.027
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Inhibition of allergic inflammation by supplementation with 5-hydroxytryptophan. Am J Physiol Lung Cell Mol Physiol. 2012 Oct 15; 303(8):L642-60.
Score: 0.026
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The effect of rosuvastatin in a murine model of influenza A infection. PLoS One. 2012; 7(4):e35788.
Score: 0.026
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Alcohol worsens acute lung injury by inhibiting alveolar sodium transport through the adenosine A1 receptor. PLoS One. 2012; 7(1):e30448.
Score: 0.025
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Minimizing oxidation and stable nanoscale dispersion improves the biocompatibility of graphene in the lung. Nano Lett. 2011 Dec 14; 11(12):5201-7.
Score: 0.025
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Proteasomal inhibition after injury prevents fibrosis by modulating TGF-ß(1) signalling. Thorax. 2012 Feb; 67(2):139-46.
Score: 0.025
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Linking air pollution exposure with thrombosis. Blood. 2011 Sep 01; 118(9):2636-7.
Score: 0.025
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Hypoxia leads to Na,K-ATPase downregulation via Ca(2+) release-activated Ca(2+) channels and AMPK activation. Mol Cell Biol. 2011 Sep; 31(17):3546-56.
Score: 0.024
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Particulate matter air pollution causes oxidant-mediated increase in gut permeability in mice. Part Fibre Toxicol. 2011 Jun 09; 8:19.
Score: 0.024
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Particulate matter-induced lung inflammation increases systemic levels of PAI-1 and activates coagulation through distinct mechanisms. PLoS One. 2011 Apr 11; 6(4):e18525.
Score: 0.024
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Leptin promotes fibroproliferative acute respiratory distress syndrome by inhibiting peroxisome proliferator-activated receptor-?. Am J Respir Crit Care Med. 2011 Jun 01; 183(11):1490-8.
Score: 0.024
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Epithelial cell death is an important contributor to oxidant-mediated acute lung injury. Am J Respir Crit Care Med. 2011 Apr 15; 183(8):1043-54.
Score: 0.023
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Update in environmental and occupational medicine 2009. Am J Respir Crit Care Med. 2010 Jun 01; 181(11):1174-80.
Score: 0.023
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Biocompatible nanoscale dispersion of single-walled carbon nanotubes minimizes in vivo pulmonary toxicity. Nano Lett. 2010 May 12; 10(5):1664-70.
Score: 0.022
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Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity. Proc Natl Acad Sci U S A. 2010 May 11; 107(19):8788-93.
Score: 0.022
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Proteasomal regulation of pulmonary fibrosis. Proc Am Thorac Soc. 2010 Feb; 7(1):77-83.
Score: 0.022
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Beta-catenin/T-cell factor signaling is activated during lung injury and promotes the survival and migration of alveolar epithelial cells. J Biol Chem. 2010 Jan 29; 285(5):3157-67.
Score: 0.022
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Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio. Free Radic Biol Med. 2009 May 15; 46(10):1386-91.
Score: 0.021
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Proapoptotic Noxa is required for particulate matter-induced cell death and lung inflammation. FASEB J. 2009 Jul; 23(7):2055-64.
Score: 0.021
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Mitochondrial complex III-generated oxidants activate ASK1 and JNK to induce alveolar epithelial cell death following exposure to particulate matter air pollution. J Biol Chem. 2009 Jan 23; 284(4):2176-86.
Score: 0.020
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Stretch-induced activation of AMP kinase in the lung requires dystroglycan. Am J Respir Cell Mol Biol. 2008 Dec; 39(6):666-72.
Score: 0.020
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Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway. J Clin Invest. 2007 Oct; 117(10):2952-61.
Score: 0.019
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Alveolar epithelial beta2-adrenergic receptors. Am J Respir Cell Mol Biol. 2008 Feb; 38(2):127-34.
Score: 0.019
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The intrinsic apoptotic pathway is required for lipopolysaccharide-induced lung endothelial cell death. J Immunol. 2007 Aug 01; 179(3):1834-41.
Score: 0.019
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Electroporation-mediated gene transfer of the Na+,K+ -ATPase rescues endotoxin-induced lung injury. Am J Respir Crit Care Med. 2007 Sep 15; 176(6):582-90.
Score: 0.018
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Adenosine regulation of alveolar fluid clearance. Proc Natl Acad Sci U S A. 2007 Mar 06; 104(10):4083-8.
Score: 0.018
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Leptin resistance protects mice from hyperoxia-induced acute lung injury. Am J Respir Crit Care Med. 2007 Mar 15; 175(6):587-94.
Score: 0.018
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p53 mediates particulate matter-induced alveolar epithelial cell mitochondria-regulated apoptosis. Am J Respir Crit Care Med. 2006 Dec 01; 174(11):1229-38.
Score: 0.017
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Air pollution impairs lung's ability to clear edema fluid. Am J Cardiol. 2006 Aug 01; 98(3):423-4.
Score: 0.017
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Proapoptotic Bid is required for pulmonary fibrosis. Proc Natl Acad Sci U S A. 2006 Mar 21; 103(12):4604-9.
Score: 0.017
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Airborne particulate matter inhibits alveolar fluid reabsorption in mice via oxidant generation. Am J Respir Cell Mol Biol. 2006 Jun; 34(6):670-6.
Score: 0.017
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Mechanisms of pulmonary edema clearance. Am J Physiol Lung Cell Mol Physiol. 2005 Nov; 289(5):L685-95.
Score: 0.016
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Interdependency of beta-adrenergic receptors and CFTR in regulation of alveolar active Na+ transport. Circ Res. 2005 May 13; 96(9):999-1005.
Score: 0.016
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Potential genetic therapies for acute lung injury. Curr Gene Ther. 2004 Dec; 4(4):487-95.
Score: 0.015
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beta(2)-Agonists for treatment of pulmonary edema: ready for clinical studies? Crit Care Med. 2004 Jul; 32(7):1607-8.
Score: 0.015
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Upregulation of alveolar epithelial active Na+ transport is dependent on beta2-adrenergic receptor signaling. Circ Res. 2004 Apr 30; 94(8):1091-100.
Score: 0.015
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Effects of beta2-adrenergic receptor overexpression on alveolar epithelial active transport. J Allergy Clin Immunol. 2002 Dec; 110(6 Suppl):S242-6.
Score: 0.013
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Comparison of surfactant and perfluorochemical liquid enhanced adenovirus-mediated gene transfer in normal rat lung. Mol Ther. 2002 Jul; 6(1):43-9.
Score: 0.013
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Acute lung injury does not impair adenoviral-mediated gene transfer to the alveolar epithelium. Chest. 2002 Mar; 121(3 Suppl):33S-34S.
Score: 0.013
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Enhancement of alveolar epithelial beta(2)-adrenergic receptor function via gene transfer. Chest. 2002 Mar; 121(3 Suppl):45S-46S.
Score: 0.013
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P311 Promotes Lung Fibrosis via Stimulation of Transforming Growth Factor-ß1, -ß2, and -ß3 Translation. Am J Respir Cell Mol Biol. 2019 02; 60(2):221-231.
Score: 0.010
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Influenza A Virus Infection Induces Muscle Wasting via IL-6 Regulation of the E3 Ubiquitin Ligase Atrogin-1. J Immunol. 2019 01 15; 202(2):484-493.
Score: 0.010
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Lung-specific loss of a3 laminin worsens bleomycin-induced pulmonary fibrosis. Am J Respir Cell Mol Biol. 2015 Apr; 52(4):503-12.
Score: 0.008
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Oxidized phospholipids protect against lung injury and endothelial barrier dysfunction caused by heat-inactivated Staphylococcus aureus. Am J Physiol Lung Cell Mol Physiol. 2015 Mar 15; 308(6):L550-62.
Score: 0.008
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Lung-specific loss of the laminin a3 subunit confers resistance to mechanical injury. J Cell Sci. 2011 Sep 01; 124(Pt 17):2927-37.
Score: 0.006
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Effects of body temperature on ventilator-induced lung injury. J Crit Care. 2005 Mar; 20(1):66-73.
Score: 0.004
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Acute hyperoxic lung injury does not impede adenoviral-mediated alveolar gene transfer. Am J Respir Crit Care Med. 2002 Feb 15; 165(4):521-6.
Score: 0.003
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beta(2)-adrenergic receptor overexpression increases alveolar fluid clearance and responsiveness to endogenous catecholamines in rats. Circ Res. 2001 Nov 09; 89(10):907-14.
Score: 0.003