Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities.

Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities. Protein Sci. 1997 Sep; 6(9):1806-24.

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subject areas

Amino Acid Sequence
Amyloid beta-Protein Precursor
Animals
Aprotinin
Base Sequence
Binding Sites
Cattle
Chymotrypsin
Crystallization
Crystallography, X-Ray
Models, Molecular
Mutagenesis
Protein Conformation
Protein Engineering
Structure-Activity Relationship
Trypsin

authors with profiles

Anthony Kossiakoff