KarenFrankKaren M. Frank0.000000000000000.000000000000002908Frank, KarenM.Assoc Prof-Clinical Deptplugins:TwitterTwitterprns:coAuthorOfcoauthor ofprns:emailEncryptedemail addressprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:middleNamemiddle name or initialvivo:orcidIdORCID idvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 1005082Authorship 101433227533330Diehl BC, Frank KAdvances in neonatal care : official journal of the National Association of Neonatal NursesA Multifaceted Nursing Role to Comply With Neonatal Transport Regulations in Maryland: The TR/DR Nurse. Adv Neonatal Care. 2016 Oct; 16(5):360-368.Adv Neonatal Care2016-10-01T00:00:002016A Multifaceted Nursing Role to Comply With Neonatal Transport Regulations in Maryland: The TR/DR Nurse.27629902Dekker JP, Frank KMJournal of clinical microbiologyNext-Generation Epidemiology: Using Real-Time Core Genome Multilocus Sequence Typing To Support Infection Control Policy. J Clin Microbiol. 2016 12; 54(12):2850-2853.J Clin Microbiol2016-09-14T00:00:002016Next-Generation Epidemiology: Using Real-Time Core Genome Multilocus Sequence Typing To Support Infection Control Policy.Authorship 1024091028373194Davison JR, Lohith KM, Wang X, Bobyk K, Mandadapu SR, Lee SL, Cencic R, Nelson J, Simpkins S, Frank KM, Pelletier J, Myers CL, Piotrowski J, Smith HE, Bewley CAAntimicrobial agents and chemotherapyA New Natural Product Analog of Blasticidin S Reveals Cellular Uptake Facilitated by the NorA Multidrug Transporter. Antimicrob Agents Chemother. 2017 06; 61(6).Antimicrob Agents Chemother2017-05-24T00:00:002017A New Natural Product Analog of Blasticidin S Reveals Cellular Uptake Facilitated by the NorA Multidrug Transporter.Authorship 104119928506784Decker BK, Lau AF, Dekker JP, Spalding CD, Sinaii N, Conlan S, Henderson DK, Segre JA, Frank KM, Palmore TNClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious DiseasesHealthcare personnel intestinal colonization with multidrug-resistant organisms. Clin Microbiol Infect. 2018 Jan; 24(1):82.e1-82.e4.Clin Microbiol Infect2017-05-12T00:00:002017Healthcare personnel intestinal colonization with multidrug-resistant organisms.D001426Chemicals & Drugs1808610.630933Bacterial ProteinsAuthorship 1058288Authorship 106271528650723Donohue PK, Norvell M, Boss RD, Shepard J, Frank K, Patron C, Crowe TYJournal of palliative medicineHospital Chaplains: Through the Eyes of Parents of Hospitalized Children. J Palliat Med. 2017 12; 20(12):1352-1358.J Palliat Med2017-06-26T00:00:002017Hospital Chaplains: Through the Eyes of Parents of Hospitalized Children.28659317Chen M, Conlan S, Lau AF, Dekker JP, Deming C, NISC Comparative Sequencing Program, Henderson DK, Frank KM, Palmore TN, Segre JAJournal of clinical microbiologyWhole-Genome Sequencing Overrules a Suspected Case of Carbapenem-Resistant Enterobacter cloacae Transmission. J Clin Microbiol. 2017 09; 55(9):2868-2870.J Clin Microbiol2017-06-28T00:00:002017Whole-Genome Sequencing Overrules a Suspected Case of Carbapenem-Resistant Enterobacter cloacae Transmission.D001618Chemicals & Drugs21510.940458beta-LactamasesD004755Living Beings15210.982942EnterobacteriaceaeMedicine-General Internal MedicineMedicine-Infectious DiseasesMicrobiologyAuthorship 1119251Authorship 11607816Authorship 1167247Authorship 1225083Authorship 1249427Authorship 125294129982557Matson MJ, Stock F, Shupert WL, Bushmaker T, Feldmann F, Bishop WB, Frank KM, Dekker JP, Chertow DS, Munster VJThe Journal of infectious diseasesCompatibility of Maximum-Containment Virus-Inactivation Protocols With Identification of Bacterial Coinfections by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry. J Infect Dis. 2018 11 22; 218(suppl_5):S297-S300.J Infect Dis2018-11-22T00:00:002018Compatibility of Maximum-Containment Virus-Inactivation Protocols With Identification of Bacterial Coinfections by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry.25533735Frank K, Esbensen AJJournal of intellectual disability research : JIDRFine motor and self-care milestones for individuals with Down syndrome using a Retrospective Chart Review. J Intellect Disabil Res. 2015 Aug; 59(8):719-29.J Intellect Disabil Res2014-12-23T00:00:002014Fine motor and self-care milestones for individuals with Down syndrome using a Retrospective Chart Review.30447809Frank KMCritical care nursing clinics of North AmericaFetal Surgery and Delayed Cord Clamping: Neonatal Implications. Crit Care Nurs Clin North Am. 2018 Dec; 30(4):499-507.Crit Care Nurs Clin North Am2018-10-16T00:00:002018Fetal Surgery and Delayed Cord Clamping: Neonatal Implications.30098394Panch SR, Bikkani T, Vargas V, Procter J, Atkins JW, Guptill V, Frank KM, Lau AF, Stroncek DFBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow TransplantationProspective Evaluation of a Practical Guideline for Managing Positive Sterility Test Results in Cell Therapy Products. Biol Blood Marrow Transplant. 2019 01; 25(1):172-178.Biol Blood Marrow Transplant2018-08-09T00:00:002018Prospective Evaluation of a Practical Guideline for Managing Positive Sterility Test Results in Cell Therapy Products.29021151Lemon JK, Khil PP, Frank KM, Dekker JPJournal of clinical microbiologyRapid Nanopore Sequencing of Plasmids and Resistance Gene Detection in Clinical Isolates. J Clin Microbiol. 2017 12; 55(12):3530-3543.J Clin Microbiol2017-10-11T00:00:002017Rapid Nanopore Sequencing of Plasmids and Resistance Gene Detection in Clinical Isolates.29437920Weingarten RA, Johnson RC, Conlan S, Ramsburg AM, Dekker JP, Lau AF, Khil P, Odom RT, Deming C, Park M, Thomas PJ, NISC Comparative Sequencing Program, Henderson DK, Palmore TN, Segre JA, Frank KMmBioGenomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of Bacterial Plasmids Conferring Carbapenem Resistance. mBio. 2018 02 06; 9(1).mBio2018-02-06T00:00:002018Genomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of Bacterial Plasmids Conferring Carbapenem Resistance.Authorship 1261041230586509Johnson RC, Deming C, Conlan S, Zellmer CJ, Michelin AV, Lee-Lin S, Thomas PJ, Park M, Weingarten RA, Less J, Dekker JP, Frank KM, Musser KA, McQuiston JR, Henderson DK, Lau AF, Palmore TN, Segre JAThe New England journal of medicineInvestigation of a Cluster of Sphingomonas koreensis Infections. N Engl J Med. 2018 12 27; 379(26):2529-2539.N Engl J Med2018-12-27T00:00:002018Investigation of a Cluster of Sphingomonas koreensis Infections.Authorship 126959730679057Lerner AM, Bennett JE, Pittaluga S, Khil PP, Youn JH, Fahle GA, Frank KM, Dekker JP, Jerussi TD, Sun C, Wiestner A, Gea-Banacloche JDiagnostic microbiology and infectious diseaseProtracted course of disseminated adenovirus disease with necrotizing granulomas in the liver. Diagn Microbiol Infect Dis. 2019 Jun; 94(2):180-182.Diagn Microbiol Infect Dis2019-01-02T00:00:002019Protracted course of disseminated adenovirus disease with necrotizing granulomas in the liver.Authorship 127069430541938England MR, Stock F, Gebo JET, Frank KM, Lau AFJournal of clinical microbiologyComprehensive Evaluation of Compendial USP<71>, BacT/Alert Dual-T, and Bactec FX for Detection of Product Sterility Testing Contaminants. J Clin Microbiol. 2019 02; 57(2).J Clin Microbiol2019-01-30T00:00:002019Comprehensive Evaluation of Compendial USP<71>, BacT/Alert Dual-T, and Bactec FX for Detection of Product Sterility Testing Contaminants.EricPamerEric Pamer41.7886000000000087.598699999999993819Pamer, EricProfessorAuthorship 132923731530672Khil PP, Dulanto Chiang A, Ho J, Youn JH, Lemon JK, Gea-Banacloche J, Frank KM, Parta M, Bonomo RA, Dekker JPmBioDynamic Emergence of Mismatch Repair Deficiency Facilitates Rapid Evolution of Ceftazidime-Avibactam Resistance in Pseudomonas aeruginosa Acute Infection. mBio. 2019 09 17; 10(5).mBio2019-09-17T00:00:002019Dynamic Emergence of Mismatch Repair Deficiency Facilitates Rapid Evolution of Ceftazidime-Avibactam Resistance in Pseudomonas aeruginosa Acute Infection.Authorship 1334859Authorship 133549329889729Desai A, Aucott S, Frank K, Silbert-Flagg JAdvances in neonatal care : official journal of the National Association of Neonatal NursesComparing N-PASS and NIPS: Improving Pain Measurement in the Neonate. Adv Neonatal Care. 2018 Aug; 18(4):260-266.Adv Neonatal Care2018-08-01T00:00:002018Comparing N-PASS and NIPS: Improving Pain Measurement in the Neonate.31594809Conlan S, Lau AF, Deming C, Spalding CD, Lee-Lin S, Thomas PJ, Park M, Dekker JP, Frank KM, Palmore TN, Segre JAmBioPlasmid Dissemination and Selection of a Multidrug-Resistant Klebsiella pneumoniae Strain during Transplant-Associated Antibiotic Therapy. mBio. 2019 10 08; 10(5).mBio2019-10-08T00:00:002019Plasmid Dissemination and Selection of a Multidrug-Resistant Klebsiella pneumoniae Strain during Transplant-Associated Antibiotic Therapy.D008826Procedures681420.945408Microbial Sensitivity TestsAuthorship 1335913031616388Lau AF, Walchak RC, Miller HB, Slechta ES, Kamboj K, Riebe K, Robertson AE, Gilbreath JJ, Mitchell KF, Wallace MA, Bryson AL, Balada-Llasat JM, Bulman A, Buchan BW, Burnham CD, Butler-Wu S, Desai U, Doern CD, Hanson KE, Henderson CM, Kostrzewa M, Ledeboer NA, Maier T, Pancholi P, Schuetz AN, Shi G, Wengenack NL, Zhang SX, Zelazny AM, Frank KMFrontiers in microbiologyMulticenter Study Demonstrates Standardization Requirements for Mold Identification by MALDI-TOF MS. Front Microbiol. 2019; 10:2098.Front Microbiol2019-09-20T00:00:002019Multicenter Study Demonstrates Standardization Requirements for Mold Identification by MALDI-TOF MS.Authorship 1342341031711969Wilkie DJ, Yao Y, Ezenwa MO, Suarez ML, Dyal BW, Gill A, Hipp T, Shea R, Miller J, Frank K, Nardi N, Murray M, Glendenning J, Perez J, Carrasco JD, Shuey D, Angulo V, McCurry T, Martin J, Butler A, Wang ZJ, Molokie REJournal of pain and symptom managementA Stepped-Wedge Randomized Controlled Trial: Effects of eHealth Interventions for Pain Control Among Adults With Cancer in Hospice. J Pain Symptom Manage. 2020 03; 59(3):626-636.J Pain Symptom Manage2019-11-09T00:00:002019A Stepped-Wedge Randomized Controlled Trial: Effects of eHealth Interventions for Pain Control Among Adults With Cancer in Hospice.D010957Chemicals & Drugs1432870.92898PlasmidsAuthorship 140786632920431Das S, Lau AF, Youn JH, Khil PP, Zelazny AM, Frank KMJournal of clinical virology : the official publication of the Pan American Society for Clinical VirologyPooled Testing for Surveillance of SARS-CoV-2 in Asymptomatic Individuals. J Clin Virol. 2020 11; 132:104619.J Clin Virol2020-09-03T00:00:002020Pooled Testing for Surveillance of SARS-CoV-2 in Asymptomatic Individuals.Authorship 1414881533052363Barat B, Das S, De Giorgi V, Henderson DK, Kopka S, Lau AF, Miller T, Moriarty T, Palmore TN, Sawney S, Spalding C, Tanjutco P, Wortmann G, Zelazny AM, Frank KMmedRxiv : the preprint server for health sciencesPooled Saliva Specimens for SARS-CoV-2 Testing. medRxiv. 2020 Oct 05.medRxiv2020-10-05T00:00:002020Pooled Saliva Specimens for SARS-CoV-2 Testing.Chicago60637IL2.525270.00713376424research areas0.3605150.0325366coauthor of36.73567.6183660similar to1175selected publicationsKammiHenriksenKammi Henriksen0.000000000000000.000000000000003033Henriksen, KammiAssociate ProfessorAuthorship 141610633080426Kline A, Putnam NE, Youn JH, East A, Das S, Frank KM, Zelazny AMDiagnostic microbiology and infectious diseaseDacron swab and PBS are acceptable alternatives to flocked swab and viral transport media for SARS-CoV-2. Diagn Microbiol Infect Dis. 2021 Jan; 99(1):115209.Diagn Microbiol Infect Dis2020-09-16T00:00:002020Dacron swab and PBS are acceptable alternatives to flocked swab and viral transport media for SARS-CoV-2.Authorship 142035733165614McKeeby JW, Siwy CM, Revoir J, Carlson SD, Joyce MD, Bailin H, Frank KM, Krumlauf M, Matlock AM, Lee LM, Sparks M, Barnes T, Liu Y, Row CH, Schmitt JM, Smith D, Zelazny AM, Lonnerdal D, Coffey PSJournal of the American Medical Informatics Association : JAMIAUnveiling the silent threat among us: leveraging health information technology in the search for asymptomatic COVID 19 healthcare workers. J Am Med Inform Assoc. 2021 02 15; 28(2):377-383.J Am Med Inform Assoc2021-02-15T00:00:002021Unveiling the silent threat among us: leveraging health information technology in the search for asymptomatic COVID 19 healthcare workers.Authorship 1423774233140061Huang N, Perez P, Kato T, Mikami Y, Okuda K, Gilmore RC, DomÃnguez Conde C, Gasmi B, Stein S, Beach M, Pelayo E, Maldonado J, LaFont B, Padilla R, Murrah V, Maile R, Lovell W, Wallet S, Bowman NM, Meinig SL, Wolfgang MC, Choudhury SN, Novotny M, Aevermann BD, Scheuermann R, Cannon G, Anderson C, Marchesan J, Bush M, Freire M, Kimple A, Herr DL, Rabin J, Grazioli A, French BN, Pranzatelli T, Chiorini JA, Kleiner DE, Pittaluga S, Hewitt S, Burbelo PD, Chertow D, Frank K, Lee J, Boucher RC, Teichmann SA, Warner BM, Byrd KMmedRxiv : the preprint server for health sciencesIntegrated Single-Cell Atlases Reveal an Oral SARS-CoV-2 Infection and Transmission Axis. medRxiv. 2020 Oct 27.medRxiv2020-10-27T00:00:002020Integrated Single-Cell Atlases Reveal an Oral SARS-CoV-2 Infection and Transmission Axis.Authorship 1424881533262219Barat B, Das S, De Giorgi V, Henderson DK, Kopka S, Lau AF, Miller T, Moriarty T, Palmore TN, Sawney S, Spalding C, Tanjutco P, Wortmann G, Zelazny AM, Frank KMJournal of clinical microbiologyPooled Saliva Specimens for SARS-CoV-2 Testing. J Clin Microbiol. 2021 02 18; 59(3).J Clin Microbiol2021-02-18T00:00:002021Pooled Saliva Specimens for SARS-CoV-2 Testing.Authorship 1427465Authorship 14274210Authorship 1427446Authorship 1427454Authorship 1427475Authorship 14284518Authorship 1428601010716994Gu Y, Sekiguchi J, Gao Y, Dikkes P, Frank K, Ferguson D, Hasty P, Chun J, Alt FWProceedings of the National Academy of Sciences of the United States of AmericaDefective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice. Proc Natl Acad Sci U S A. 2000 Mar 14; 97(6):2668-73.Proc Natl Acad Sci U S A2000-03-14T00:00:002000Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice.10555147Minamisawa S, Hoshijima M, Chu G, Ward CA, Frank K, Gu Y, Martone ME, Wang Y, Ross J, Kranias EG, Giles WR, Chien KRCellChronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy. Cell. 1999 Oct 29; 99(3):313-22.Cell1999-10-29T00:00:001999Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy.33323397Zhang Q, Ma C, Duan Y, Heinrich B, Rosato U, Diggs LP, Ma L, Roy S, Fu Q, Brown ZJ, Wabitsch S, Thovarai V, Fu J, Feng D, Ruf B, Cui LL, Subramanyam V, Frank KM, Wang S, Kleiner DE, Ritz T, Rupp C, Gao B, Longerich T, Kroemer A, Wang XW, Ruchirawat M, Korangy F, Schnabl B, Trinchieri G, Greten TFCancer discoveryGut Microbiome Directs Hepatocytes to Recruit MDSCs and Promote Cholangiocarcinoma. Cancer Discov. 2021 05; 11(5):1248-1267.Cancer Discov2020-12-15T00:00:002020Gut Microbiome Directs Hepatocytes to Recruit MDSCs and Promote Cholangiocarcinoma.9390689Gu Y, Seidl KJ, Rathbun GA, Zhu C, Manis JP, van der Stoep N, Davidson L, Cheng HL, Sekiguchi JM, Frank K, Stanhope-Baker P, Schlissel MS, Roth DB, Alt FWImmunityGrowth retardation and leaky SCID phenotype of Ku70-deficient mice. Immunity. 1997 Nov; 7(5):653-65.Immunity1997-11-01T00:00:001997Growth retardation and leaky SCID phenotype of Ku70-deficient mice.11779495Sharpless NE, Ferguson DO, O'Hagan RC, Castrillon DH, Lee C, Farazi PA, Alson S, Fleming J, Morton CC, Frank K, Chin L, Alt FW, DePinho RAMolecular cellImpaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions. Mol Cell. 2001 Dec; 8(6):1187-96.Mol Cell2001-12-01T00:00:002001Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions.11248063Sekiguchi J, Ferguson DO, Chen HT, Yang EM, Earle J, Frank K, Whitlow S, Gu Y, Xu Y, Nussenzweig A, Alt FWProceedings of the National Academy of Sciences of the United States of AmericaGenetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development. Proc Natl Acad Sci U S A. 2001 Mar 13; 98(6):3243-8.Proc Natl Acad Sci U S A2001-03-06T00:00:002001Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development.11232282Sekiguchi JM, Gao Y, Gu Y, Frank K, Sun Y, Chaudhuri J, Zhu C, Cheng HL, Manis J, Ferguson D, Davidson L, Greenberg ME, Alt FWCold Spring Harbor symposia on quantitative biologyNonhomologous end-joining proteins are required for V(D)J recombination, normal growth, and neurogenesis. Cold Spring Harb Symp Quant Biol. 1999; 64:169-81.Cold Spring Harb Symp Quant Biol1999-01-01T00:00:001999Nonhomologous end-joining proteins are required for V(D)J recombination, normal growth, and neurogenesis.Medicine-Pulmonary and Critical CareAuthorship 144028233532808Guan B, Frank KM, Maldonado JO, Beach M, Pelayo E, Warner BM, Hufnagel RBmedRxiv : the preprint server for health sciencesSensitive extraction-free SARS-CoV-2 RNA virus detection using a novel RNA preparation method. medRxiv. 2021 Feb 01.medRxiv2021-02-01T00:00:002021Sensitive extraction-free SARS-CoV-2 RNA virus detection using a novel RNA preparation method.Authorship 1450604733767405Huang N, Pérez P, Kato T, Mikami Y, Okuda K, Gilmore RC, Conde CD, Gasmi B, Stein S, Beach M, Pelayo E, Maldonado JO, Lafont BA, Jang SI, Nasir N, Padilla RJ, Murrah VA, Maile R, Lovell W, Wallet SM, Bowman NM, Meinig SL, Wolfgang MC, Choudhury SN, Novotny M, Aevermann BD, Scheuermann RH, Cannon G, Anderson CW, Lee RE, Marchesan JT, Bush M, Freire M, Kimple AJ, Herr DL, Rabin J, Grazioli A, Das S, French BN, Pranzatelli T, Chiorini JA, Kleiner DE, Pittaluga S, Hewitt SM, Burbelo PD, Chertow D, NIH COVID-19 Autopsy Consortium, HCA Oral and Craniofacial Biological Network, Frank K, Lee J, Boucher RC, Teichmann SA, Warner BM, Byrd KMNature medicineSARS-CoV-2 infection of the oral cavity and saliva. Nat Med. 2021 05; 27(5):892-903.Nat Med2021-03-25T00:00:002021SARS-CoV-2 infection of the oral cavity and saliva.19587341Frank KM, Hogarth DK, Miller JL, Mandal S, Mease PJ, Samulski RJ, Weisgerber GA, Hart JThe New England journal of medicineInvestigation of the cause of death in a gene-therapy trial. N Engl J Med. 2009 Jul 09; 361(2):161-9.N Engl J Med2009-07-09T00:00:002009Investigation of the cause of death in a gene-therapy trial.18923009Charnot-Katsikas A, Dorafshar AH, Aycock JK, David MZ, Weber SG, Frank KMJournal of clinical microbiologyTwo cases of necrotizing fasciitis due to Acinetobacter baumannii. J Clin Microbiol. 2009 Jan; 47(1):258-63.J Clin Microbiol2008-10-15T00:00:002008Two cases of necrotizing fasciitis due to Acinetobacter baumannii.21714673Frank KM, Schneewind O, Shieh WJThe New England journal of medicineInvestigation of a researcher's death due to septicemic plague. N Engl J Med. 2011 Jun 30; 364(26):2563-4.N Engl J Med2011-06-30T00:00:002011Investigation of a researcher's death due to septicemic plague.Authorship 1476966Authorship 147810734198050Totten AH, Youn JH, Roder A, Ghedin E, Palmore TN, Frank KM, Das S, Zelazny AMJournal of clinical virology : the official publication of the Pan American Society for Clinical VirologyDetection of SARS-CoV2 variants by Mesa Accula. J Clin Virol. 2021 08; 141:104901.J Clin Virol2021-06-19T00:00:002021Detection of SARS-CoV2 variants by Mesa Accula.34165324Bellerose MM, Clark AE, Youn JH, Weingarten RA, Crooks CM, Dekker JP, Frank KMJournal of clinical microbiologyManual Reading of Sensititre Broth Microdilution System Panels Improves Accuracy of Susceptibility Reporting for Polymyxin Antibiotics. J Clin Microbiol. 2021 08 18; 59(9):e0033221.J Clin Microbiol2021-08-18T00:00:002021Manual Reading of Sensititre Broth Microdilution System Panels Improves Accuracy of Susceptibility Reporting for Polymyxin Antibiotics.Authorship 148891234396082Guan B, Frank KM, Maldonado JO, Beach M, Pelayo E, Warner BM, Hufnagel RBiScienceSensitive extraction-free SARS-CoV-2 RNA virus detection using a chelating resin. iScience. 2021 09 24; 24(9):102960.iScience2021-08-09T00:00:002021Sensitive extraction-free SARS-CoV-2 RNA virus detection using a chelating resin.Authorship 1511211034724999Totten AH, Matlock AM, Bailin H, Revoir J, Siwy CM, Joyce M, Coffey P, Henderson DK, Palmore TN, Frank KM, McKeeby JInfection control and hospital epidemiologyExperience with voluntary severe acute respiratory coronavirus virus 2 (SARS-CoV-2) testing of asymptomatic staff at the National Institutes of Health for one year. Infect Control Hosp Epidemiol. 2022 11; 43(11):1661-1663.Infect Control Hosp Epidemiol2021-11-02T00:00:002021Experience with voluntary severe acute respiratory coronavirus virus 2 (SARS-CoV-2) testing of asymptomatic staff at the National Institutes of Health for one year.Authorship 155110235636826Das S, Frank KMClinics in laboratory medicineStrategies for Scaling up SARS-CoV-2 Molecular Testing Capacity. Clin Lab Med. 2022 06; 42(2):261-282.Clin Lab Med2022-03-08T00:00:002022Strategies for Scaling up SARS-CoV-2 Molecular Testing Capacity.Authorship 1557494635753512Similuk MN, Yan J, Ghosh R, Oler AJ, Franco LM, Setzer MR, Kamen M, Jodarski C, DiMaggio T, Davis J, Gore R, Jamal L, Borges A, Gentile N, Niemela J, Lowe C, Jevtich K, Yu Y, Hullfish H, Hsu AP, Hong C, Littel P, Seifert BA, Milner J, Johnston JJ, Cheng X, Li Z, Veltri D, Huang K, Kaladi K, Barnett J, Zhang L, Vlasenko N, Fan Y, Karlins E, Ganakammal SR, Gilmore R, Tran E, Yun A, Mackey J, Yazhuk S, Lack J, Kuram V, Cao W, Huse S, Frank K, Fahle G, Rosenzweig S, Su Y, Hwang S, Bi W, Bennett J, Myles IA, De Ravin SS, Fuss I, Strober W, Bielekova B, Almeida de Jesus A, Goldbach-Mansky R, Williamson P, Kumar K, Dempsy C, Frischmeyer-Guerrerio P, Fisch R, Bolan H, Metcalfe DD, Komarow H, Carter M, Druey KM, Sereti I, Dropulic L, Klion AD, Khoury P, O' Connell EM, Holland-Thomas NC, Brown T, McDermott DH, Murphy PM, Bundy V, Keller MD, Peng C, Kim H, Norman S, Delmonte OM, Kang E, Su HC, Malech H, Freeman A, Zerbe C, Uzel G, Bergerson JRE, Rao VK, Olivier KN, Lyons JJ, Lisco A, Cohen JI, Lionakis MS, Biesecker LG, Xirasagar S, Notarangelo LD, Holland SM, Walkiewicz MAThe Journal of allergy and clinical immunologyClinical exome sequencing of 1000 families with complex immune phenotypes: Toward comprehensive genomic evaluations. J Allergy Clin Immunol. 2022 10; 150(4):947-954.J Allergy Clin Immunol2022-06-24T00:00:002022Clinical exome sequencing of 1000 families with complex immune phenotypes: Toward comprehensive genomic evaluations.https://pamerlab.uchicago.eduPamer Lab websitehttps://voices.uchicago.edu/missiakaslab/Missiakas Labhttps://rubinlab.uchicago.edu/Rubin Lab Sitehttp://dfi.uchicago.eduDuchossois Family Institutehttp://headandneckpathology.com/Head and Neck Pathologyhttps://voices.uchicago.edu/grosspathology/Gross Pathologyhttps://www.uchicagomedicine.org/conditions-services/inflammatory-bowel-diseaseInflammatory Bowel Disease Center@nicoleciprianiIBDMD2002-02-28NIHFRANK, KAREN M1997-03-01XRCC4 AND V<D>J RECOMBINATION AND DNA REPAIRK08AI001428Principal Investigator25348152Pauli NT, Kim HK, Falugi F, Huang M, Dulac J, Henry Dunand C, Zheng NY, Kaur K, Andrews SF, Huang Y, DeDent A, Frank KM, Charnot-Katsikas A, Schneewind O, Wilson PCThe Journal of experimental medicineStaphylococcus aureus infection induces protein A-mediated immune evasion in humans. J Exp Med. 2014 Nov 17; 211(12):2331-9.J Exp Med2014-10-27T00:00:002014Staphylococcus aureus infection induces protein A-mediated immune evasion in humans.MedicinePathologyPediatricsUniversity of ChicagoDouglas KyleHogarthDouglas Kyle Hogarth41.78927490000000-87.601250000000001208Hogarth, Douglas KyleProfessorLarryKociolekLarry Kociolek41.78927490000000-87.601250000000001531Kociolek, LarryClinical AssociateDominiqueMissiakas029gGLIcGOf5hHlsaUXv9Gq0+s+oDominique Missiakas41.78927490000000-87.601250000000002010Missiakas, DominiqueProfessorVineetAroraVineet Arora41.78927490000000-87.601250000000002306Arora, VineetProfessorStephen G.WeberStephen G. Weber41.78927490000000-87.601250000000002476Weber, Stephen G.ProfessorDavid T.RubinDavid T. Rubin41.78927490000000-87.60125000000000256Rubin, David T.ProfessorJoyceAycockJoyce K. Aycock41.78927490000000-87.60125000000000450Aycock, JoyceJohnHartJohn Hart41.78927490000000-87.60125000000000470Hart, JohnProfessorVeraTesicVera Tesic41.78927490000000-87.60125000000000869Tesic, Vera0000-0003-0004-8445Professortrue1true1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1Assoc Prof-Clinical DeptAssoc Prof-Clinical Depttrue1ProfessorProfessortrue1ProfessorProfessortrue1Clinical AssociateClinical Associatetrue1ProfessorProfessortrue1Clinical AssociateClinical AssociateAuthorship 655131Authorship 6597613Authorship 675916Authorship 683581Authorship 695613Authorship 717761Authorship 706871Authorship 747834Authorship 7483014Authorship 746921Authorship 767255Authorship 784365Authorship 7922312Authorship 687485Authorship 709416Authorship 740073Authorship 741585Authorship 7752349875844Gao Y, Sun Y, Frank KM, Dikkes P, Fujiwara Y, Seidl KJ, Sekiguchi JM, Rathbun GA, Swat W, Wang J, Bronson RT, Malynn BA, Bryans M, Zhu C, Chaudhuri J, Davidson L, Ferrini R, Stamato T, Orkin SH, Greenberg ME, Alt FWCellA critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis. Cell. 1998 Dec 23; 95(7):891-902.Cell1998-12-23T00:00:001998A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis.9823897Frank KM, Sekiguchi JM, Seidl KJ, Swat W, Rathbun GA, Cheng HL, Davidson L, Kangaloo L, Alt FWNatureLate embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV. Nature. 1998 Nov 12; 396(6707):173-7.Nature1998-11-12T00:00:001998Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV.10823907Ferguson DO, Sekiguchi JM, Chang S, Frank KM, Gao Y, DePinho RA, Alt FWProceedings of the National Academy of Sciences of the United States of AmericaThe nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations. Proc Natl Acad Sci U S A. 2000 Jun 06; 97(12):6630-3.Proc Natl Acad Sci U S A2000-06-06T00:00:002000The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations.25398999Lau AF, Wang H, Weingarten RA, Drake SK, Suffredini AF, Chen Y, Gucek M, Youn JH, Stock F, Tso H, DeLeo J, Cimino JJ, Frank KM, Dekker JPJournal of clinical microbiologyReply to "Tn4401 carrying blaKPC is inserted within another insertion in pKpQIL and related plasmids". J Clin Microbiol. 2014 Dec; 52(12):4450.J Clin Microbiol2014-12-01T00:00:002014Reply to "Tn4401 carrying blaKPC is inserted within another insertion in pKpQIL and related plasmids".24227878Charnot-Katsikas A, Tesic V, Boonlayangoor S, Bethel C, Frank KMJournal of medical microbiologyProspective evaluation of the VITEK MS for the routine identification of bacteria and yeast in the clinical microbiology laboratory: assessment of accuracy of identification and turnaround time. J Med Microbiol. 2014 Feb; 63(Pt 2):235-241.J Med Microbiol2013-11-13T00:00:002013Prospective evaluation of the VITEK MS for the routine identification of bacteria and yeast in the clinical microbiology laboratory: assessment of accuracy of identification and turnaround time.10786799Gao Y, Ferguson DO, Xie W, Manis JP, Sekiguchi J, Frank KM, Chaudhuri J, Horner J, DePinho RA, Alt FWNatureInterplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development. Nature. 2000 Apr 20; 404(6780):897-900.Nature2000-04-20T00:00:002000Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development.12760055Ferguson DO, Sekiguchi JM, Frank KM, Gao Y, Sharpless NE, Gu Y, Manis J, DePinho RA, Alt FWCold Spring Harbor symposia on quantitative biologyThe interplay between nonhomologous end-joining and cell cycle checkpoint factors in development, genomic stability, and tumorigenesis. Cold Spring Harb Symp Quant Biol. 2000; 65:395-403.Cold Spring Harb Symp Quant Biol2000-01-01T00:00:002000The interplay between nonhomologous end-joining and cell cycle checkpoint factors in development, genomic stability, and tumorigenesis.10911993Frank KM, Sharpless NE, Gao Y, Sekiguchi JM, Ferguson DO, Zhu C, Manis JP, Horner J, DePinho RA, Alt FWMolecular cellDNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway. Mol Cell. 2000 Jun; 5(6):993-1002.Mol Cell2000-06-01T00:00:002000DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway.16412978Foster RE, Nnakwe C, Woo L, Frank KMBiochemical and biophysical research communicationsMonoubiquitination of the nonhomologous end joining protein XRCC4. Biochem Biophys Res Commun. 2006 Mar 03; 341(1):175-83.Biochem Biophys Res Commun2006-01-06T00:00:002006Monoubiquitination of the nonhomologous end joining protein XRCC4.16949575Woo LL, Futami K, Shimamoto A, Furuichi Y, Frank KMExperimental cell researchThe Rothmund-Thomson gene product RECQL4 localizes to the nucleolus in response to oxidative stress. Exp Cell Res. 2006 Oct 15; 312(17):3443-57.Exp Cell Res2006-08-02T00:00:002006The Rothmund-Thomson gene product RECQL4 localizes to the nucleolus in response to oxidative stress.15194694Wang YG, Nnakwe C, Lane WS, Modesti M, Frank KMThe Journal of biological chemistryPhosphorylation and regulation of DNA ligase IV stability by DNA-dependent protein kinase. J Biol Chem. 2004 Sep 03; 279(36):37282-90.J Biol Chem2004-06-11T00:00:002004Phosphorylation and regulation of DNA ligase IV stability by DNA-dependent protein kinase.24850353Lau AF, Wang H, Weingarten RA, Drake SK, Suffredini AF, Garfield MK, Chen Y, Gucek M, Youn JH, Stock F, Tso H, DeLeo J, Cimino JJ, Frank KM, Dekker JPJournal of clinical microbiologyA rapid matrix-assisted laser desorption ionization-time of flight mass spectrometry-based method for single-plasmid tracking in an outbreak of carbapenem-resistant Enterobacteriaceae. J Clin Microbiol. 2014 Aug; 52(8):2804-12.J Clin Microbiol2014-05-21T00:00:002014A rapid matrix-assisted laser desorption ionization-time of flight mass spectrometry-based method for single-plasmid tracking in an outbreak of carbapenem-resistant Enterobacteriaceae.1010Authorship 846193Authorship 8452424Authorship 8465418Authorship 844622Authorship 846334Authorship 847396Authorship 84728226338860Lau AF, Fahle GA, Kemp MA, Jassem AN, Dekker JP, Frank KMJournal of clinical microbiologyClinical Performance of Check-Direct CPE, a Multiplex PCR for Direct Detection of bla(KPC), bla(NDM) and/or bla(VIM), and bla(OXA)-48 from Perirectal Swabs. J Clin Microbiol. 2015 Dec; 53(12):3729-37.J Clin Microbiol2015-09-02T00:00:002015Clinical Performance of Check-Direct CPE, a Multiplex PCR for Direct Detection of bla(KPC), bla(NDM) and/or bla(VIM), and bla(OXA)-48 from Perirectal Swabs.10738042Dorman SE, Cannon ME, Telford SR, Frank KM, Churchill WHTransfusionFulminant babesiosis treated with clindamycin, quinine, and whole-blood exchange transfusion. Transfusion. 2000 Mar; 40(3):375-80.Transfusion2000-03-01T00:00:002000Fulminant babesiosis treated with clindamycin, quinine, and whole-blood exchange transfusion.26511484Viau R, Frank KM, Jacobs MR, Wilson B, Kaye K, Donskey CJ, Perez F, Endimiani A, Bonomo RAClinical microbiology reviewsIntestinal Carriage of Carbapenemase-Producing Organisms: Current Status of Surveillance Methods. Clin Microbiol Rev. 2016 Jan; 29(1):1-27.Clin Microbiol Rev2016-01-01T00:00:002016Intestinal Carriage of Carbapenemase-Producing Organisms: Current Status of Surveillance Methods.25232178Conlan S, Thomas PJ, Deming C, Park M, Lau AF, Dekker JP, Snitkin ES, Clark TA, Luong K, Song Y, Tsai YC, Boitano M, Dayal J, Brooks SY, Schmidt B, Young AC, Thomas JW, Bouffard GG, Blakesley RW, NISC Comparative Sequencing Program, Mullikin JC, Korlach J, Henderson DK, Frank KM, Palmore TN, Segre JAScience translational medicineSingle-molecule sequencing to track plasmid diversity of hospital-associated carbapenemase-producing Enterobacteriaceae. Sci Transl Med. 2014 Sep 17; 6(254):254ra126.Sci Transl Med2014-09-17T00:00:002014Single-molecule sequencing to track plasmid diversity of hospital-associated carbapenemase-producing Enterobacteriaceae.24264989Iida N, Dzutsev A, Stewart CA, Smith L, Bouladoux N, Weingarten RA, Molina DA, Salcedo R, Back T, Cramer S, Dai RM, Kiu H, Cardone M, Naik S, Patri AK, Wang E, Marincola FM, Frank KM, Belkaid Y, Trinchieri G, Goldszmid RSScience (New York, N.Y.)Commensal bacteria control cancer response to therapy by modulating the tumor microenvironment. Science. 2013 Nov 22; 342(6161):967-70.Science2013-11-22T00:00:002013Commensal bacteria control cancer response to therapy by modulating the tumor microenvironment.25239410Haspel RL, Rinder HM, Frank KM, Wagner J, Ali AM, Fisher PB, Parks ER, Training Residents in Genomics (TRIG) Working GroupAmerican journal of clinical pathologyThe current state of resident training in genomic pathology: a comprehensive analysis using the resident in-service examination. Am J Clin Pathol. 2014 Oct; 142(4):445-51.Am J Clin Pathol2014-10-01T00:00:002014The current state of resident training in genomic pathology: a comprehensive analysis using the resident in-service examination.26004640Dekker JP, Frank KMClinics in laboratory medicineSalmonella, Shigella, and yersinia. Clin Lab Med. 2015 Jun; 35(2):225-46.Clin Lab Med2015-04-02T00:00:002015Salmonella, Shigella, and yersinia.Authorship 85206426338858Youn JH, Drake SK, Weingarten RA, Frank KM, Dekker JP, Lau AFJournal of clinical microbiologyClinical Performance of a Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Method for Detection of Certain blaKPC-Containing Plasmids. J Clin Microbiol. 2016 Jan; 54(1):35-42.J Clin Microbiol2015-09-02T00:00:002015Clinical Performance of a Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Method for Detection of Certain blaKPC-Containing Plasmids.Authorship 87565826888898Hughes HY, Conlan SP, Lau AF, Dekker JP, Michelin AV, Youn JH, Henderson DK, Frank KM, Segre JA, Palmore TNJournal of clinical microbiologyDetection and Whole-Genome Sequencing of Carbapenemase-Producing Aeromonas hydrophila Isolates from Routine Perirectal Surveillance Culture. J Clin Microbiol. 2016 Apr; 54(4):1167-70.J Clin Microbiol2016-02-17T00:00:002016Detection and Whole-Genome Sequencing of Carbapenemase-Producing Aeromonas hydrophila Isolates from Routine Perirectal Surveillance Culture.Authorship 87814527052736Myles IA, Reckhow JD, Williams KW, Sastalla I, Frank KM, Datta SKBMC microbiologyA method for culturing Gram-negative skin microbiota. BMC Microbiol. 2016 Apr 06; 16:60.BMC Microbiol2016-04-06T00:00:002016A method for culturing Gram-negative skin microbiota.Authorship 89084926912758Blosser SJ, Drake SK, Andrasko JL, Henderson CM, Kamboj K, Antonara S, Mijares L, Conville P, Frank KM, Harrington SM, Balada-Llasat JM, Zelazny AMJournal of clinical microbiologyMulticenter Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Study for Identification of Clinically Relevant Nocardia spp. J Clin Microbiol. 2016 05; 54(5):1251-8.J Clin Microbiol2016-02-24T00:00:002016Multicenter Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Study for Identification of Clinically Relevant Nocardia spp.Authorship 912301327353756Conlan S, Park M, Deming C, Thomas PJ, Young AC, Coleman H, Sison C, NISC Comparative Sequencing Program, Weingarten RA, Lau AF, Dekker JP, Palmore TN, Frank KM, Segre JAmBioPlasmid Dynamics in KPC-Positive Klebsiella pneumoniae during Long-Term Patient Colonization. mBio. 2016 Jun 28; 7(3).mBio2016-06-28T00:00:002016Plasmid Dynamics in KPC-Positive Klebsiella pneumoniae during Long-Term Patient Colonization.Authorship 91500527417839Conlan S, Lau AF, NISC Comparative Sequencing Program, Palmore TN, Frank KM, Segre JAGenome announcementsComplete Genome Sequence of a Klebsiella pneumoniae Strain Carrying blaNDM-1 on a Multidrug Resistance Plasmid. Genome Announc. 2016 Jul 14; 4(4).Genome Announc2016-07-14T00:00:002016Complete Genome Sequence of a Klebsiella pneumoniae Strain Carrying blaNDM-1 on a Multidrug Resistance Plasmid.Authorship 92449927270289Hardiman CA, Weingarten RA, Conlan S, Khil P, Dekker JP, Mathers AJ, Sheppard AE, Segre JA, Frank KMAntimicrobial agents and chemotherapyHorizontal Transfer of Carbapenemase-Encoding Plasmids and Comparison with Hospital Epidemiology Data. Antimicrob Agents Chemother. 2016 08; 60(8):4910-9.Antimicrob Agents Chemother2016-07-22T00:00:002016Horizontal Transfer of Carbapenemase-Encoding Plasmids and Comparison with Hospital Epidemiology Data.ManuelUtsetManuel F. Utset0.000000000000000.000000000000002734Utset, ManuelClinical AssociateNicole A.CiprianiNicole A. Cipriani0.000000000000000.000000000000002756Cipriani, Nicole A.ProfessorJason X.Cheng3WN6BK9bGuTcn31EdUXm/Hbq9t+85aYQdX1vJason X. Cheng0.000000000000000.000000000000002798Cheng, Jason X.Associate Professor22733574Frank KM, Zhou T, Moreno-Vinasco L, Hollett B, Garcia JG, Bubeck Wardenburg JInfection and immunityHost response signature to Staphylococcus aureus alpha-hemolysin implicates pulmonary Th17 response. Infect Immun. 2012 Sep; 80(9):3161-9.Infect Immun2012-06-25T00:00:002012Host response signature to Staphylococcus aureus alpha-hemolysin implicates pulmonary Th17 response.21926978Inoshima I, Inoshima N, Wilke GA, Powers ME, Frank KM, Wang Y, Bubeck Wardenburg JNature medicineA Staphylococcus aureus pore-forming toxin subverts the activity of ADAM10 to cause lethal infection in mice. Nat Med. 2011 Sep 18; 17(10):1310-4.Nat Med2011-09-18T00:00:002011A Staphylococcus aureus pore-forming toxin subverts the activity of ADAM10 to cause lethal infection in mice.Authorship 97125927826141Sun W, Weingarten RA, Xu M, Southall N, Dai S, Shinn P, Sanderson PE, Williamson PR, Frank KM, Zheng WEmerging microbes & infectionsRapid antimicrobial susceptibility test for identification of new therapeutics and drug combinations against multidrug-resistant bacteria. Emerg Microbes Infect. 2016 Nov 09; 5(11):e116.Emerg Microbes Infect2016-11-09T00:00:002016Rapid antimicrobial susceptibility test for identification of new therapeutics and drug combinations against multidrug-resistant bacteria.DanielArberDaniel Arber0.000000000000000.000000000000003406Arber, DanielProfessorAuthorship 99345327917566Engorn BM, Kahntroff SL, Frank KM, Singh S, Harvey HA, Barkulis CT, Barnett AM, Olambiwonnu OO, Heitmiller ES, Greenberg RSPaediatric anaesthesiaPerioperative hypothermia in neonatal intensive care unit patients: effectiveness of a thermoregulation intervention and associated risk factors. Paediatr Anaesth. 2017 Feb; 27(2):196-204.Paediatr Anaesth2016-12-05T00:00:002016Perioperative hypothermia in neonatal intensive care unit patients: effectiveness of a thermoregulation intervention and associated risk factors.