YoshifumiSonobeYoshifumi Sonobe0.000000000000000.000000000000003021Sonobe, YoshifumiPost Doctoral Scholarprns:coAuthorOfcoauthor ofprns:emailEncryptedemail addressFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 100952827079835Liang J, Takeuchi H, Jin S, Noda M, Li H, Doi Y, Kawanokuchi J, Sonobe Y, Mizuno T, Suzumura ABrain researchCorrigendum to "Glutamate induces neurotrophic factor production from microglia via protein kinase C pathway" [Brain Research 1322 (2010) 8-23]. Brain Res. 2016 Aug 01; 1644:306-307.Brain Res2016-04-05T00:00:002016Corrigendum to "Glutamate induces neurotrophic factor production from microglia via protein kinase C pathway" [Brain Research 1322 (2010) 8-23].D000690Disorders451820.86772Amyotrophic Lateral SclerosisD004681Disorders21570.962693Encephalomyelitis, Autoimmune, ExperimentalJeffreyHubbell3Wp8CaMQFeD5hHlsaUXv9Gq0+s+oJeffrey Hubbell41.7886000000000087.598699999999993473Hubbell, JeffreyBarry L. MacLean ProfessorMicrobiologyNeurobiologyAuthorship 125268129792928Sonobe Y, Ghadge G, Masaki K, Sendoel A, Fuchs E, Roos RPNeurobiology of diseaseTranslation of dipeptide repeat proteins from the C9ORF72 expanded repeat is associated with cellular stress. Neurobiol Dis. 2018 08; 116:155-165.Neurobiol Dis2018-05-22T00:00:002018Translation of dipeptide repeat proteins from the C9ORF72 expanded repeat is associated with cellular stress.Authorship 127704230742696Masaki K, Sonobe Y, Ghadge G, Pytel P, Roos RPPLoS pathogensTDP-43 proteinopathy in Theiler's murine encephalomyelitis virus infection. PLoS Pathog. 2019 02; 15(2):e1007574.PLoS Pathog2019-02-11T00:00:002019TDP-43 proteinopathy in Theiler's murine encephalomyelitis virus infection.Authorship 134834231837419Ghadge GD, Sonobe Y, Camarena A, Drigotas C, Rigo F, Ling KK, Roos RPNeurobiology of diseaseKnockdown of GADD34 in neonatal mutant SOD1 mice ameliorates ALS. Neurobiol Dis. 2020 03; 136:104702.Neurobiol Dis2019-12-16T00:00:002019Knockdown of GADD34 in neonatal mutant SOD1 mice ameliorates ALS.Pritzker Institute for Molecular EngineeringAuthorship 136485232217641Masaki K, Sonobe Y, Ghadge G, Pytel P, Lépine P, Pernin F, Cui QL, Antel JP, Zandee S, Prat A, Roos RPNeurology(R) neuroimmunology & neuroinflammationRNA-binding protein altered expression and mislocalization in MS. Neurol Neuroimmunol Neuroinflamm. 2020 05; 7(3).Neurol Neuroimmunol Neuroinflamm2020-03-26T00:00:002020RNA-binding protein altered expression and mislocalization in MS.Chicago60637IL2.404220.010655280research areas2.113540.09116034coauthor of33.60884.3421660similar to1145selected publicationsAnaSolodkinAna Solodkin0.000000000000000.000000000000003041Solodkin, AnaASSOCIATE PROFESSOR Authorship 150366134654821Sonobe Y, Aburas J, Krishnan G, Fleming AC, Ghadge G, Islam P, Warren EC, Gu Y, Kankel MW, Brown AEX, Kiskinis E, Gendron TF, Gao FB, Roos RP, Kratsios PNature communicationsA C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation. Nat Commun. 2021 10 15; 12(1):6025.Nat Commun2021-10-15T00:00:002021A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation.Authorship 155157435648796Gleason AC, Ghadge G, Chen J, Sonobe Y, Roos RPPloS oneMachine learning predicts translation initiation sites in neurologic diseases with nucleotide repeat expansions. PLoS One. 2022; 17(6):e0256411.PLoS One2022-06-01T00:00:002022Machine learning predicts translation initiation sites in neurologic diseases with nucleotide repeat expansions.ShabaanaKhaderShabaana Khader41.7886000000000087.598699999999994229Khader, ShabaanaProfessorD057180Disorders7270.958314Frontotemporal DementiaAuthorship 159570336142475Gleason AC, Ghadge G, Sonobe Y, Roos RPInternational journal of molecular sciencesKozak Similarity Score Algorithm Identifies Alternative Translation Initiation Codons Implicated in Cancers. Int J Mol Sci. 2022 Sep 12; 23(18).Int J Mol Sci2022-09-12T00:00:002022Kozak Similarity Score Algorithm Identifies Alternative Translation Initiation Codons Implicated in Cancers.D0000738856180.972338C9orf72 Proteinhttp://voices.uchicago.edu/drsisodialab/Sisodia Labhttp://www.kratsioslab.orgKratsios LabAikateriniMarkopoulouAikaterini Markopoulou0.000000000000000.000000000000003127Markopoulou, AikateriniClinical Asst ProfessorD017628Anatomy481020.927159MicrogliaNeurologyPathologyUniversity of ChicagoPeterPytelx3JwH6QZOfnamXNnYUHhvWD+6g==Peter Pytel41.78927490000000-87.601250000000001091Pytel, PeterProfessorRaymond P.RoosxXBmBLI1F+nMg3Vob0H3vWfp+4Wo6r1Xc3h9eaOOFmI=Raymond P. Roos41.78927490000000-87.601250000000001191Roos, Raymond P.Professor37675986Sonobe Y, Lee S, Krishnan G, Gu Y, Kwon DY, Gao FB, Roos RP, Kratsios PeLifeTranslation of dipeptide repeat proteins in C9ORF72 ALS/FTD through unique and redundant AUG initiation codons. Elife. 2023 09 07; 12.Elife2023-09-07T00:00:002023Translation of dipeptide repeat proteins in C9ORF72 ALS/FTD through unique and redundant AUG initiation codons.Authorship 1662171GhanashyamGhadgeGhanashyam Ghadge41.78927490000000-87.601250000000002070Ghadge, GhanashyamSenior Research AssociateThomas F.GajewskiThomas F. Gajewski41.78927490000000-87.60125000000000355Gajewski, Thomas F.ProfessorSangram S.SisodiaxHF6ArIaHeX5hHlsaUXv9Gq0+s+oSangram S. Sisodia41.78927490000000-87.60125000000000510Sisodia, Sangram S.Professortrue1ASSOCIATE PROFESSOR ASSOCIATE PROFESSOR true1Clinical Assistant ProfessorClinical Assistant Professortrue1Clinical ProfessorClinical Professortrue1Post Doctoral ScholarPost Doctoral Scholartrue1Postdoctoral ScholarPostdoctoral Scholartrue1Clinical Asst ProfessorClinical Asst Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Senior Research AssociateSenior Research Associatetrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Barry L. MacLean ProfessorBarry L. MacLean ProfessorAuthorship 662905Authorship 658023Authorship 663585Authorship 680368Authorship 673602Authorship 673216Authorship 695635Authorship 692913Authorship 698892Authorship 698732Authorship 722068Authorship 737522Authorship 726621Authorship 721152Authorship 738605Authorship 731121Authorship 724687Authorship 746961Authorship 731857Authorship 744672Authorship 738516Authorship 747399Authorship 764105Authorship 749893Authorship 777053Authorship 771257Authorship 788126Authorship 784291Authorship 774835Authorship 665121Authorship 6927314Authorship 708631Authorship 745585Authorship 74067625313834Wang Y, Jin S, Sonobe Y, Cheng Y, Horiuchi H, Parajuli B, Kawanokuchi J, Mizuno T, Takeuchi H, Suzumura APloS oneInterleukin-1ß induces blood-brain barrier disruption by downregulating Sonic hedgehog in astrocytes. PLoS One. 2014; 9(10):e110024.PLoS One2014-10-14T00:00:002014Interleukin-1ß induces blood-brain barrier disruption by downregulating Sonic hedgehog in astrocytes.22036952Endong L, Shijie J, Sonobe Y, Di M, Hua L, Kawanokuchi J, Mizuno T, Suzumura AJournal of neuroimmunologyThe gap-junction inhibitor carbenoxolone suppresses the differentiation of Th17 cells through inhibition of IL-23 expression in antigen presenting cells. J Neuroimmunol. 2011 Dec 15; 240-241:58-64.J Neuroimmunol2011-10-28T00:00:002011The gap-junction inhibitor carbenoxolone suppresses the differentiation of Th17 cells through inhibition of IL-23 expression in antigen presenting cells.25062013Doi Y, Takeuchi H, Mizoguchi H, Fukumoto K, Horiuchi H, Jin S, Kawanokuchi J, Parajuli B, Sonobe Y, Mizuno T, Suzumura APloS oneGranulocyte-colony stimulating factor attenuates oligomeric amyloid ß neurotoxicity by activation of neprilysin. PLoS One. 2014; 9(7):e103458.PLoS One2014-07-25T00:00:002014Granulocyte-colony stimulating factor attenuates oligomeric amyloid ß neurotoxicity by activation of neprilysin.23593505Doi Y, Takeuchi H, Horiuchi H, Hanyu T, Kawanokuchi J, Jin S, Parajuli B, Sonobe Y, Mizuno T, Suzumura APloS oneFingolimod phosphate attenuates oligomeric amyloid ß-induced neurotoxicity via increased brain-derived neurotrophic factor expression in neurons. PLoS One. 2013; 8(4):e61988.PLoS One2013-04-12T00:00:002013Fingolimod phosphate attenuates oligomeric amyloid ß-induced neurotoxicity via increased brain-derived neurotrophic factor expression in neurons.22306300Parajuli B, Sonobe Y, Kawanokuchi J, Doi Y, Noda M, Takeuchi H, Mizuno T, Suzumura AJournal of neuroimmunologyImmunoglobulin G(1) immune complex upregulates interferon-?-induced nitric oxide production via ERK1/2 activation in murine microglia. J Neuroimmunol. 2012 Mar; 244(1-2):57-62.J Neuroimmunol2012-02-04T00:00:002012Immunoglobulin G(1) immune complex upregulates interferon-?-induced nitric oxide production via ERK1/2 activation in murine microglia.22323540Sonobe Y, Li H, Jin S, Kishida S, Kadomatsu K, Takeuchi H, Mizuno T, Suzumura AJournal of immunology (Baltimore, Md. : 1950)Midkine inhibits inducible regulatory T cell differentiation by suppressing the development of tolerogenic dendritic cells. J Immunol. 2012 Mar 15; 188(6):2602-11.J Immunol2012-02-08T00:00:002012Midkine inhibits inducible regulatory T cell differentiation by suppressing the development of tolerogenic dendritic cells.19212100Shijie J, Takeuchi H, Yawata I, Harada Y, Sonobe Y, Doi Y, Liang J, Hua L, Yasuoka S, Zhou Y, Noda M, Kawanokuchi J, Mizuno T, Suzumura AThe Tohoku journal of experimental medicineBlockade of glutamate release from microglia attenuates experimental autoimmune encephalomyelitis in mice. Tohoku J Exp Med. 2009 Feb; 217(2):87-92.Tohoku J Exp Med2009-02-01T00:00:002009Blockade of glutamate release from microglia attenuates experimental autoimmune encephalomyelitis in mice.21237519Hashiba N, Nagayama S, Araya SI, Inada H, Sonobe Y, Suzumura A, Matsui MJournal of neuroimmunologyPhenytoin at optimum doses ameliorates experimental autoimmune encephalomyelitis via modulation of immunoregulatory cells. J Neuroimmunol. 2011 Apr; 233(1-2):112-9.J Neuroimmunol2011-01-14T00:00:002011Phenytoin at optimum doses ameliorates experimental autoimmune encephalomyelitis via modulation of immunoregulatory cells.21071446Noda M, Doi Y, Liang J, Kawanokuchi J, Sonobe Y, Takeuchi H, Mizuno T, Suzumura AThe Journal of biological chemistryFractalkine attenuates excito-neurotoxicity via microglial clearance of damaged neurons and antioxidant enzyme heme oxygenase-1 expression. J Biol Chem. 2011 Jan 21; 286(3):2308-19.J Biol Chem2010-11-11T00:00:002010Fractalkine attenuates excito-neurotoxicity via microglial clearance of damaged neurons and antioxidant enzyme heme oxygenase-1 expression.25535736Jin S, Sonobe Y, Kawanokuchi J, Horiuchi H, Cheng Y, Wang Y, Mizuno T, Takeuchi H, Suzumura APloS oneInterleukin-34 restores blood-brain barrier integrity by upregulating tight junction proteins in endothelial cells. PLoS One. 2014; 9(12):e115981.PLoS One2014-12-23T00:00:002014Interleukin-34 restores blood-brain barrier integrity by upregulating tight junction proteins in endothelial cells.21346235Zhou Y, Sonobe Y, Akahori T, Jin S, Kawanokuchi J, Noda M, Iwakura Y, Mizuno T, Suzumura AJournal of immunology (Baltimore, Md. : 1950)IL-9 promotes Th17 cell migration into the central nervous system via CC chemokine ligand-20 produced by astrocytes. J Immunol. 2011 Apr 01; 186(7):4415-21.J Immunol2011-02-23T00:00:002011IL-9 promotes Th17 cell migration into the central nervous system via CC chemokine ligand-20 produced by astrocytes.15804443Sonobe Y, Yawata I, Kawanokuchi J, Takeuchi H, Mizuno T, Suzumura ABrain researchProduction of IL-27 and other IL-12 family cytokines by microglia and their subpopulations. Brain Res. 2005 Apr 08; 1040(1-2):202-7.Brain Res2005-04-08T00:00:002005Production of IL-27 and other IL-12 family cytokines by microglia and their subpopulations.21349253Yasuoka S, Kawanokuchi J, Parajuli B, Jin S, Doi Y, Noda M, Sonobe Y, Takeuchi H, Mizuno T, Suzumura ABrain researchProduction and functions of IL-33 in the central nervous system. Brain Res. 2011 Apr 18; 1385:8-17.Brain Res2011-02-22T00:00:002011Production and functions of IL-33 in the central nervous system.17905201Jin S, Kawanokuchi J, Mizuno T, Wang J, Sonobe Y, Takeuchi H, Suzumura ABrain researchInterferon-beta is neuroprotective against the toxicity induced by activated microglia. Brain Res. 2007 Nov 07; 1179:140-6.Brain Res2007-09-04T00:00:002007Interferon-beta is neuroprotective against the toxicity induced by activated microglia.22999806Ma D, Jin S, Li E, Doi Y, Parajuli B, Noda M, Sonobe Y, Mizuno T, Suzumura AJournal of neuroimmunologyThe neurotoxic effect of astrocytes activated with toll-like receptor ligands. J Neuroimmunol. 2013 Jan 15; 254(1-2):10-8.J Neuroimmunol2012-09-19T00:00:002012The neurotoxic effect of astrocytes activated with toll-like receptor ligands.24357806Parajuli B, Sonobe Y, Horiuchi H, Takeuchi H, Mizuno T, Suzumura ACell death & diseaseOligomeric amyloid ß induces IL-1ß processing via production of ROS: implication in Alzheimer's disease. Cell Death Dis. 2013 Dec 19; 4:e975.Cell Death Dis2013-12-19T00:00:002013Oligomeric amyloid ß induces IL-1ß processing via production of ROS: implication in Alzheimer's disease.18319343Wang J, Takeuchi H, Sonobe Y, Jin S, Mizuno T, Miyakawa S, Fujiwara M, Nakamura Y, Kato T, Muramatsu H, Muramatsu T, Suzumura AProceedings of the National Academy of Sciences of the United States of AmericaInhibition of midkine alleviates experimental autoimmune encephalomyelitis through the expansion of regulatory T cell population. Proc Natl Acad Sci U S A. 2008 Mar 11; 105(10):3915-20.Proc Natl Acad Sci U S A2008-03-04T00:00:002008Inhibition of midkine alleviates experimental autoimmune encephalomyelitis through the expansion of regulatory T cell population.19776017Sonobe Y, Takeuchi H, Kataoka K, Li H, Jin S, Mimuro M, Hashizume Y, Sano Y, Kanda T, Mizuno T, Suzumura AThe Journal of biological chemistryInterleukin-25 expressed by brain capillary endothelial cells maintains blood-brain barrier function in a protein kinase Cepsilon-dependent manner. J Biol Chem. 2009 Nov 13; 284(46):31834-42.J Biol Chem2009-09-23T00:00:002009Interleukin-25 expressed by brain capillary endothelial cells maintains blood-brain barrier function in a protein kinase Cepsilon-dependent manner.22985514Ma D, Doi Y, Jin S, Li E, Sonobe Y, Takeuchi H, Mizuno T, Suzumura ANeuroscience lettersTGF-ß induced by interleukin-34-stimulated microglia regulates microglial proliferation and attenuates oligomeric amyloid ß neurotoxicity. Neurosci Lett. 2012 Oct 31; 529(1):86-91.Neurosci Lett2012-09-07T00:00:002012TGF-ß induced by interleukin-34-stimulated microglia regulates microglial proliferation and attenuates oligomeric amyloid ß neurotoxicity.24565075Cheng Y, Takeuchi H, Sonobe Y, Jin S, Wang Y, Horiuchi H, Parajuli B, Kawanokuchi J, Mizuno T, Suzumura AJournal of neuroimmunologySirtuin 1 attenuates oxidative stress via upregulation of superoxide dismutase 2 and catalase in astrocytes. J Neuroimmunol. 2014 Apr 15; 269(1-2):38-43.J Neuroimmunol2014-02-12T00:00:002014Sirtuin 1 attenuates oxidative stress via upregulation of superoxide dismutase 2 and catalase in astrocytes.15021962Sonobe Y, Nakane H, Watanabe T, Nakano KInflammation research : official journal of the European Histamine Research Society ... [et al.]Regulation of Con A-dependent cytokine production from CD4+ and CD8+ T lymphocytes by autosecretion of histamine. Inflamm Res. 2004 Mar; 53(3):87-92.Inflamm Res2004-02-16T00:00:002004Regulation of Con A-dependent cytokine production from CD4+ and CD8+ T lymphocytes by autosecretion of histamine.24735639Noda M, Takii K, Parajuli B, Kawanokuchi J, Sonobe Y, Takeuchi H, Mizuno T, Suzumura AJournal of neuroinflammationFGF-2 released from degenerating neurons exerts microglial-induced neuroprotection via FGFR3-ERK signaling pathway. J Neuroinflammation. 2014 Apr 16; 11:76.J Neuroinflammation2014-04-16T00:00:002014FGF-2 released from degenerating neurons exerts microglial-induced neuroprotection via FGFR3-ERK signaling pathway.18075237Sonobe Y, Jin S, Wang J, Kawanokuchi J, Takeuchi H, Mizuno T, Suzumura AThe Tohoku journal of experimental medicineChronological changes of CD4(+) and CD8(+) T cell subsets in the experimental autoimmune encephalomyelitis, a mouse model of multiple sclerosis. Tohoku J Exp Med. 2007 Dec; 213(4):329-39.Tohoku J Exp Med2007-12-01T00:00:002007Chronological changes of CD4(+) and CD8(+) T cell subsets in the experimental autoimmune encephalomyelitis, a mouse model of multiple sclerosis.15241568Nakane H, Sonobe Y, Watanabe T, Nakano KInflammation research : official journal of the European Histamine Research Society ... [et al.]Histamine: its novel role as an endogenous regulator of Con A-dependent T cell proliferation. Inflamm Res. 2004 Jul; 53(7):324-8.Inflamm Res2004-06-25T00:00:002004Histamine: its novel role as an endogenous regulator of Con A-dependent T cell proliferation.20138844Liang J, Takeuchi H, Jin S, Noda M, Li H, Doi Y, Kawanokuchi J, Sonobe Y, Mizuno T, Suzumura ABrain researchGlutamate induces neurotrophic factor production from microglia via protein kinase C pathway. Brain Res. 2010 Mar 31; 1322:8-23.Brain Res2010-02-06T00:00:002010Glutamate induces neurotrophic factor production from microglia via protein kinase C pathway.16720574Takeuchi H, Jin S, Wang J, Zhang G, Kawanokuchi J, Kuno R, Sonobe Y, Mizuno T, Suzumura AThe Journal of biological chemistryTumor necrosis factor-alpha induces neurotoxicity via glutamate release from hemichannels of activated microglia in an autocrine manner. J Biol Chem. 2006 Jul 28; 281(30):21362-21368.J Biol Chem2006-05-23T00:00:002006Tumor necrosis factor-alpha induces neurotoxicity via glutamate release from hemichannels of activated microglia in an autocrine manner.18358830Sonobe Y, Liang J, Jin S, Zhang G, Takeuchi H, Mizuno T, Suzumura ABiochemical and biophysical research communicationsMicroglia express a functional receptor for interleukin-23. Biochem Biophys Res Commun. 2008 May 23; 370(1):129-33.Biochem Biophys Res Commun2008-03-20T00:00:002008Microglia express a functional receptor for interleukin-23.21712989Takeuchi H, Mizoguchi H, Doi Y, Jin S, Noda M, Liang J, Li H, Zhou Y, Mori R, Yasuoka S, Li E, Parajuli B, Kawanokuchi J, Sonobe Y, Sato J, Yamanaka K, Sobue G, Mizuno T, Suzumura APloS oneBlockade of gap junction hemichannel suppresses disease progression in mouse models of amyotrophic lateral sclerosis and Alzheimer's disease. PLoS One. 2011; 6(6):e21108.PLoS One2011-06-21T00:00:002011Blockade of gap junction hemichannel suppresses disease progression in mouse models of amyotrophic lateral sclerosis and Alzheimer's disease.18410911Liang J, Takeuchi H, Doi Y, Kawanokuchi J, Sonobe Y, Jin S, Yawata I, Li H, Yasuoka S, Mizuno T, Suzumura ABrain researchExcitatory amino acid transporter expression by astrocytes is neuroprotective against microglial excitotoxicity. Brain Res. 2008 May 19; 1210:11-9.Brain Res2008-03-20T00:00:002008Excitatory amino acid transporter expression by astrocytes is neuroprotective against microglial excitotoxicity.21872563Mizuno T, Doi Y, Mizoguchi H, Jin S, Noda M, Sonobe Y, Takeuchi H, Suzumura AThe American journal of pathologyInterleukin-34 selectively enhances the neuroprotective effects of microglia to attenuate oligomeric amyloid-ß neurotoxicity. Am J Pathol. 2011 Oct; 179(4):2016-27.Am J Pathol2011-08-26T00:00:002011Interleukin-34 selectively enhances the neuroprotective effects of microglia to attenuate oligomeric amyloid-ß neurotoxicity.16956589Kuno R, Yoshida Y, Nitta A, Nabeshima T, Wang J, Sonobe Y, Kawanokuchi J, Takeuchi H, Mizuno T, Suzumura ABrain researchThe role of TNF-alpha and its receptors in the production of NGF and GDNF by astrocytes. Brain Res. 2006 Oct 20; 1116(1):12-8.Brain Res2006-09-07T00:00:002006The role of TNF-alpha and its receptors in the production of NGF and GDNF by astrocytes.18198214Mizuno T, Zhang G, Takeuchi H, Kawanokuchi J, Wang J, Sonobe Y, Jin S, Takada N, Komatsu Y, Suzumura AFASEB journal : official publication of the Federation of American Societies for Experimental BiologyInterferon-gamma directly induces neurotoxicity through a neuron specific, calcium-permeable complex of IFN-gamma receptor and AMPA GluR1 receptor. FASEB J. 2008 Jun; 22(6):1797-806.FASEB J2008-01-15T00:00:002008Interferon-gamma directly induces neurotoxicity through a neuron specific, calcium-permeable complex of IFN-gamma receptor and AMPA GluR1 receptor.23234315Parajuli B, Sonobe Y, Kawanokuchi J, Doi Y, Noda M, Takeuchi H, Mizuno T, Suzumura AJournal of neuroinflammationGM-CSF increases LPS-induced production of proinflammatory mediators via upregulation of TLR4 and CD14 in murine microglia. J Neuroinflammation. 2012 Dec 13; 9:268.J Neuroinflammation2012-12-13T00:00:002012GM-CSF increases LPS-induced production of proinflammatory mediators via upregulation of TLR4 and CD14 in murine microglia.22742657Li E, Noda M, Doi Y, Parajuli B, Kawanokuchi J, Sonobe Y, Takeuchi H, Mizuno T, Suzumura AJournal of neuroinflammationThe neuroprotective effects of milk fat globule-EGF factor 8 against oligomeric amyloid ß toxicity. J Neuroinflammation. 2012 Jun 28; 9:148.J Neuroinflammation2012-06-28T00:00:002012The neuroprotective effects of milk fat globule-EGF factor 8 against oligomeric amyloid ß toxicity.1010BSD-NeurologyAuthorship 91004127288521Sonobe Y, Takeuchi H, Kataoka K, Li H, Jin S, Mimuro M, Hashizume Y, Sano Y, Kanda T, Mizuno T, Suzumura AThe Journal of biological chemistryInterleukin-25 expressed by brain capillary endothelial cells maintains blood-brain barrier function in a protein kinase C?-dependent manner. J Biol Chem. 2016 Jun 10; 291(24):12573.J Biol Chem2016-06-10T00:00:002016Interleukin-25 expressed by brain capillary endothelial cells maintains blood-brain barrier function in a protein kinase C?-dependent manner.Authorship 91263527371564Noda M, Doi Y, Liang J, Kawanokuchi J, Sonobe Y, Takeuchi H, Mizuno T, Suzumura AThe Journal of biological chemistryFractalkine attenuates excito-neurotoxicity via microglial clearance of damaged neurons and antioxidant enzyme heme oxygenase-1 expression. J Biol Chem. 2016 Jul 01; 291(27):14388.J Biol Chem2016-07-01T00:00:002016Fractalkine attenuates excito-neurotoxicity via microglial clearance of damaged neurons and antioxidant enzyme heme oxygenase-1 expression.PaschalisKratsiosPaschalis Kratsios0.000000000000000.000000000000003280Kratsios, PaschalisAssociate ProfessorKaePusicKae Pusic0.000000000000000.000000000000002715Pusic, KaePostdoctoral ScholarNicholasVickNicholas Vick0.000000000000000.000000000000002808Vick, NicholasClinical ProfessorKhalilahBrownKhalilah Brown0.000000000000000.000000000000002842Brown, KhalilahClinical Assistant Professor