11303783Martys-Zage JL, Kim SH, Berechid B, Bingham SJ, Chu S, Sklar J, Nye J, Sisodia SSJournal of molecular neuroscience : MNAlzheimer Disease; Carrier Proteins; Cell Membrane; Membrane Proteins; Peptide Hydrolases; Receptors, Cell Surface; Signal Transduction; Transcription FactorsAmyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Carbamates; Cell Line, Transformed; Cell Nucleus; Dipeptides; Endopeptidases; Fetus; Fibroblasts; Green Fluorescent Proteins; Indicators and Reagents; Intercellular Signaling Peptides and Proteins; Jagged-2 Protein; Luminescent Proteins; Mice; Mice, Knockout; Peptide Fragments; Presenilin-1; Protease Inhibitors; Receptor, Notch1; Recombinant Fusion Proteins; Translocation, GeneticRequirement for presenilin 1 in facilitating lagged 2-mediated endoproteolysis and signaling of notch 1. J Mol Neurosci. 2000 Dec; 15(3):189-204.J Mol Neurosci2000-12-01T00:00:002000Requirement for presenilin 1 in facilitating lagged 2-mediated endoproteolysis and signaling of notch 1.prns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD002461Anatomy871530.966171Cell Line, TransformedD000818Living Beings1457265180.249624AnimalsD002467Anatomy2525790.827191Cell NucleusD004151Chemicals & Drugs27460.970266DipeptidesD002462Anatomy2366640.777777Cell MembraneD002219Chemicals & Drugs15190.980949CarbamatesD005347Anatomy2447290.786016FibroblastsNeurobiologyD007202Chemicals & Drugs49720.982483Indicators and ReagentsD008565Chemicals & Drugs37111940.607129Membrane ProteinsAuthorship 188318D010446Chemicals & Drugs2134600.839276Peptide FragmentsD010447Chemicals & Drugs431000.959959Peptide HydrolasesD010450Chemicals & Drugs561160.943886EndopeptidasesD005333Anatomy1172260.897951FetusD011480Chemicals & Drugs51720.962356Protease InhibitorsD014157Chemicals & Drugs40615550.562899Transcription FactorsD011956Chemicals & Drugs1622860.87673Receptors, Cell Surface0.1985950.1985951authors10.2532has subject areaD016282Chemicals & Drugs23660.965992Aspartic Acid EndopeptidasesD016564Chemicals & Drugs261430.930256Amyloid beta-Protein PrecursorD018345Living Beings43819180.695188Mice, KnockoutD036341Chemicals & Drugs1141790.911054Intercellular Signaling Peptides and ProteinsD049452Chemicals & Drugs1673050.912421Green Fluorescent ProteinsD051379Living Beings980113130.368397MiceD053764Chemicals & Drugs151000.95726Presenilin-1D051881Chemicals & Drugs41850.947333Receptor, Notch1D053829Chemicals & Drugs28930.945281Amyloid Precursor Protein SecretasesD000544Disorders974700.73465Alzheimer DiseaseD002352Chemicals & Drugs2666720.751711Carrier ProteinsD000072101460.998795Jagged-2 Proteinhttp://voices.uchicago.edu/drsisodialab/Sisodia LabD008164Chemicals & Drugs881440.940668Luminescent ProteinsD011993Chemicals & Drugs2485550.847892Recombinant Fusion ProteinsD014178Physiology902650.907259Translocation, GeneticD015398Physiology69932330.460036Signal TransductionUniversity of ChicagoSangram S.SisodiaxHF6ArIaHeX5hHlsaUXv9Gq0+s+oSangram S. Sisodia41.78927490000000-87.60125000000000510Sisodia, Sangram S.Professortrue1ProfessorProfessor