11773369Cassady KA, Gross M, Gillespie GY, Roizman BJournal of virologyCapsid; Capsid Proteins; eIF-2 Kinase; Encephalitis, Herpes Simplex; Herpesvirus 1, Human; Immediate-Early Proteins; Phosphoproteins; RNA-Binding Proteins; Viral ProteinsAnimals; Brain; Chlorocebus aethiops; Enzyme Activation; Female; HeLa Cells; Humans; Mice; Mice, Inbred CBA; Mutagenesis; Neurons; Phosphorylation; Protein Structure, Tertiary; Recombination, Genetic; Vero Cells; Virulence; Virus ReplicationSecond-site mutation outside of the U(S)10-12 domain of Deltagamma(1)34.5 herpes simplex virus 1 recombinant blocks the shutoff of protein synthesis induced by activated protein kinase R and partially restores neurovirulence. J Virol. 2002 Feb; 76(3):942-9.J Virol2002-02-01T00:00:002002Second-site mutation outside of the U(S)10-12 domain of Deltagamma(1)34.5 herpes simplex virus 1 recombinant blocks the shutoff of protein synthesis induced by activated protein kinase R and partially restores neurovirulence.prns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD000818Living Beings1457265180.249624AnimalsD001921Anatomy49222110.472349BrainD002213Anatomy17340.992358CapsidMartinGrossMartin Gross41.7886000000000087.598699999999993660Gross, MartinEmeritus/Emerita, ProfessorD004789Physiology2436920.87473Enzyme ActivationAuthorship 1229422D008808Living Beings25520.990737Mice, Inbred CBAAuthorship 199254D011995Physiology1324390.82911Recombination, GeneticD006367Anatomy1884980.889649HeLa CellsD009474Anatomy29515450.526388NeuronsD010750Chemicals & Drugs1412530.885741PhosphoproteinsD010766Phenomena34811010.802856PhosphorylationD005260Physiology1992444050.191167FemaleD006801Living Beings2262862810.130052HumansD014774Concepts & IdeasPhysiology782700.914655VirulenceD014779Physiology843190.873942Virus ReplicationD018259Living Beings412440.805823Herpesvirus 1, Human0.2153570.05383942authors10.2525has subject areaD016296Physiology1201990.949604MutagenesisD036022Chemicals & Drugs18320.990187Capsid ProteinsD017434Concepts & Ideas2687360.844002Protein Structure, TertiaryD016601Chemicals & Drugs1192440.835647RNA-Binding ProteinsD017874Chemicals & Drugs521640.885786Immediate-Early ProteinsD020803Disorders8160.982091Encephalitis, Herpes SimplexD019892Chemicals & Drugs29460.969792eIF-2 KinaseD051379Living Beings980113130.368397MiceD014709Anatomy431000.97416Vero CellsD014764Chemicals & Drugs733000.862748Viral ProteinsBSD MicrobiologyPathologyUniversity of ChicagoBernardRoizman1Wd7BaAHHaLLnnN+bUfg02fp+4Wo6r1Xc3h9eaOOFmI=Bernard Roizman41.78927490000000-87.601250000000001112Roizman, BernardEmeritus/Emerita, Professortrue1Emeritus/Emerita, ProfessorEmeritus/Emerita, Professortrue1Emeritus/Emerita, ProfessorEmeritus/Emerita, Professor