12093770Takemoto M, Sun J, Hiroki J, Shimokawa H, Liao JKCirculationDown-Regulation; Endothelium, Vascular; Nitric Oxide Synthase; Protein Serine-Threonine Kinases1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Hypoxia; Cells, Cultured; Enzyme Inhibitors; Gene Expression Regulation; Humans; Intracellular Signaling Peptides and Proteins; Nitric Oxide Synthase Type III; Pulmonary Artery; rho-Associated Kinases; RNA Stability; RNA, Messenger; Transcription, GeneticRho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase. Circulation. 2002 Jul 02; 106(1):57-62.Circulation2002-07-02T00:00:002002Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase.prns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD004730Anatomy1354350.823162Endothelium, VascularD004791Chemicals & Drugs2686320.779731Enzyme InhibitorsD005786Physiology51419170.529599Gene Expression RegulationD006801Living Beings2262862810.130052HumansD014158Physiology38111350.694138Transcription, GeneticAuthorship 2086450.2216180.2216181authors10.2516has subject areaD011651Anatomy1103050.849371Pulmonary ArteryD012333Chemicals & Drugs51619750.640012RNA, MessengerD015536Physiology2565040.86254Down-RegulationD015687Physiology671640.920544Cell HypoxiaD019001Chemicals & Drugs531250.947608Nitric Oxide SynthaseD047908Chemicals & Drugs1833780.829617Intracellular Signaling Peptides and ProteinsD052250Chemicals & Drugs36880.960794Nitric Oxide Synthase Type IIID054460Chemicals & Drugs401590.883845rho-Associated KinasesD002478Anatomy60328100.667881Cells, CulturedD019307Chemicals & Drugs11360.9790811-(5-Isoquinolinesulfonyl)-2-MethylpiperazineD020871Concepts & IdeasPhysiology35860.947918RNA StabilityMedicineUniversity of ChicagoJamesLiaoJames Liao41.78927490000000-87.60125000000000382Liao, JamesProfessortrue1ProfessorProfessor