11877460Beqaj S, Jakkaraju S, Mattingly RR, Pan D, Schuger LThe Journal of cell biologyBotulinum Toxins; Bronchi; Laminin; Mesoderm; Muscle, Smooth; rhoA GTP-Binding Protein; Stem CellsADP Ribose Transferases; Animals; Cell Differentiation; Down-Regulation; Endothelin-1; Female; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Immunohistochemistry; Lysophospholipids; Mice; Mice, Inbred ICR; Phenotype; Protein-Tyrosine Kinases; RNA, MessengerHigh RhoA activity maintains the undifferentiated mesenchymal cell phenotype, whereas RhoA down-regulation by laminin-2 induces smooth muscle myogenesis. J Cell Biol. 2002 Mar 04; 156(5):893-903.J Cell Biol2002-03-04T00:00:002002High RhoA activity maintains the undifferentiated mesenchymal cell phenotype, whereas RhoA down-regulation by laminin-2 induces smooth muscle myogenesis.prns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD000818Living Beings1457265180.249624AnimalsD002454Physiology39014560.620998Cell DifferentiationD001905Chemicals & Drugs15160.986885Botulinum ToxinsD001980Anatomy762290.897048BronchiD008246Chemicals & Drugs30630.950762LysophospholipidsD009130Anatomy763540.873482Muscle, SmoothAuthorship 202545D007150Procedures48817520.715464ImmunohistochemistryD008648Anatomy511070.9469MesodermD007797Chemicals & Drugs43850.957695LamininD005260Physiology1992444050.191167FemaleD011505Chemicals & Drugs1183020.866551Protein-Tyrosine KinasesD013234Anatomy1793500.817759Stem Cells0.2166280.2166281authors10.2522has subject areaD008813Living Beings31700.983435Mice, Inbred ICRD019332Chemicals & Drugs19410.962504Endothelin-1D020742Chemicals & Drugs41830.941129rhoA GTP-Binding ProteinD051379Living Beings980113130.368397MiceD051416Chemicals & Drugs16280.991836Focal Adhesion Protein-Tyrosine KinasesD051417Chemicals & Drugs19310.986215Focal Adhesion Kinase 1D012333Chemicals & Drugs51619750.640012RNA, MessengerD015536Physiology2565040.86254Down-RegulationD010641Physiology64723750.615854PhenotypeD036002Chemicals & Drugs440.998264ADP Ribose TransferasesPathologyUniversity of ChicagoLuciaSchugerLucia Schuger41.78927490000000-87.6012500000000087Schuger, LuciaPROFESSORtrue1PROFESSORPROFESSOR