12933792Gupta M, Sueblinvong V, Raman J, Jeevanandam V, Gupta MPThe Journal of biological chemistryCyclic AMP Response Element-Binding Protein; DNA, Single-Stranded; DNA-Binding Proteins; Gene Expression Regulation; Myocytes, Cardiac; Myosin Heavy Chains; Regulatory Sequences, Nucleic AcidAnimals; Binding Sites; Binding, Competitive; Blotting, Western; Cloning, Molecular; DNA; Genes, Reporter; Heart Diseases; HeLa Cells; Humans; Nerve Tissue Proteins; Oncogene Proteins; Protein Biosynthesis; Proto-Oncogene Proteins c-ets; RNA, Messenger; Transcription Factors; Transcription, GeneticSingle-stranded DNA-binding proteins PURalpha and PURbeta bind to a purine-rich negative regulatory element of the alpha-myosin heavy chain gene and control transcriptional and translational regulation of the gene expression. Implications in the repression of alpha-myosin heavy chain during heart failure. J Biol Chem. 2003 Nov 07; 278(45):44935-48.J Biol Chem2003-08-21T00:00:002003Single-stranded DNA-binding proteins PURalpha and PURbeta bind to a purine-rich negative regulatory element of the alpha-myosin heavy chain gene and control transcriptional and translational regulation of the gene expression. Implications in the repression of alpha-myosin heavy chain during heart failure.prns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD000818Living Beings1457265180.249646AnimalsD001665Chemicals & Drugs32910980.797837Binding SitesD004268Chemicals & Drugs35612080.630119DNA-Binding ProteinsD004247Chemicals & Drugs36112930.643083DNAD005786Physiology51419170.529635Gene Expression RegulationD006331Disorders1282900.807368Heart DiseasesD009419Chemicals & Drugs2005030.780123Nerve Tissue ProteinsAuthorship 231524Authorship 231531D006367Anatomy1884980.889667HeLa CellsD014157Chemicals & Drugs40615550.562935Transcription FactorsD012045Chemicals & Drugs991480.918748Regulatory Sequences, Nucleic AcidD006801Living Beings2262862810.130064HumansD014158Physiology38111350.694173Transcription, GeneticD014176Physiology1533780.834518Protein BiosynthesisD015513Chemicals & Drugs37590.958757Oncogene Proteins0.2397320.0599332authors10.2524has subject areaD017362Chemicals & Drugs46660.975241Cyclic AMP Response Element-Binding ProteinD017930Genes & Molecular Sequences1622660.934749Genes, ReporterD018995Chemicals & Drugs58880.960304Myosin Heavy ChainsD050783Chemicals & Drugs17250.982757Proto-Oncogene Proteins c-etsD032383Anatomy892750.806611Myocytes, CardiacD012333Chemicals & Drugs51619750.640048RNA, MessengerD015153PhenomenaProcedures3187810.861181Blotting, WesternD001667Physiology991450.976838Binding, CompetitiveD003001Procedures2246460.90158Cloning, Molecularhttp://maheshguptalaboratory.weebly.comMahesh Gupta LaboratoryD004277Chemicals & Drugs45920.945275DNA, Single-StrandedSurgeryUniversity of ChicagoValluvanJeevanandamValluvan Jeevanandam41.78927490000000-87.601250000000002130Jeevanandam, ValluvanProfessorMahesh P.GuptaMahesh P. Gupta41.78927490000000-87.601250000000002244Gupta, Mahesh P.Professortrue1ProfessorProfessortrue1ProfessorProfessorSurgery-Cardiac