17785202Kang S, Dong S, Gu TL, Guo A, Cohen MS, Lonial S, Khoury HJ, Fabbro D, Gilliland DG, Bergsagel PL, Taunton J, Polakiewicz RD, Chen JCancer cellCell Transformation, Neoplastic; MAP Kinase Signaling System; Multiple Myeloma; Receptor, Fibroblast Growth Factor, Type 3; Ribosomal Protein S6 Kinases, 90-kDaApoptosis; Binding Sites; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Mitogen-Activated Protein Kinase Kinases; Models, Biological; Phosphorylation; RNA Interference; TyrosineFGFR3 activates RSK2 to mediate hematopoietic transformation through tyrosine phosphorylation of RSK2 and activation of the MEK/ERK pathway. Cancer Cell. 2007 Sep; 12(3):201-14.Cancer Cell2007-09-01T00:00:002007FGFR3 activates RSK2 to mediate hematopoietic transformation through tyrosine phosphorylation of RSK2 and activation of the MEK/ERK pathway.prns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:orcidIdORCID idPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD001665Chemicals & Drugs32910980.797837Binding SitesD002471Disorders1774270.812593Cell Transformation, NeoplasticD004789Physiology2436920.874749Enzyme ActivationD010766Phenomena34811010.802883PhosphorylationD006801Living Beings2262862810.130064HumansJingChenJing Chen41.7886000000000087.598699999999993958Chen, Jing0000-0002-5376-9062ProfessorD014443Chemicals & Drugs741330.960512TyrosineAuthorship 143246130.3169890.3169891authors10.2517has subject areaMedicine-Hematology and OncologyD009101Disorders823070.737453Multiple MyelomaD034622PhenomenaPhysiology1993680.889319RNA InterferenceD017209Physiology41016780.608673ApoptosisD049109Physiology43515710.639771Cell ProliferationD020929Chemicals & Drugs581010.936604Mitogen-Activated Protein Kinase KinasesD038744Chemicals & Drugs690.989987Ribosomal Protein S6 Kinases, 90-kDaD020935Physiology1141920.917309MAP Kinase Signaling SystemD048049Chemicals & Drugs801150.944227Extracellular Signal-Regulated MAP KinasesD045744Anatomy46824210.643269Cell Line, TumorD051498Chemicals & Drugs17210.983303Receptor, Fibroblast Growth Factor, Type 3https://sites.google.com/view/jingchen-lab-uchicago/homeChen LabD008954Concepts & IdeasDevices59917480.587465Models, BiologicalUniversity of Chicagotrue1ProfessorProfessor