15534117Azuma T, Otsuki T, Kuzushima K, Froelich CJ, Fujita S, Yasukawa MClinical cancer research : an official journal of the American Association for Cancer ResearchCytoplasmic Granules; Multiple Myeloma; T-Lymphocytes, Cytotoxic; WT1 ProteinsAntigens, Neoplasm; Bone Marrow Cells; Calcium; Cell Line; Cell Line, Tumor; Chromium; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme-Linked Immunosorbent Assay; Exocytosis; Flow Cytometry; Genes, MHC Class I; Humans; Immunotherapy; Interferon-gamma; Lymphoma; Macrolides; Membrane Glycoproteins; Peptides; Perforin; Pore Forming Cytotoxic Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Treatment OutcomeMyeloma cells are highly sensitive to the granule exocytosis pathway mediated by WT1-specific cytotoxic T lymphocytes. Clin Cancer Res. 2004 Nov 01; 10(21):7402-12.Clin Cancer Res2004-11-01T00:00:002004Myeloma cells are highly sensitive to the granule exocytosis pathway mediated by WT1-specific cytotoxic T lymphocytes.prns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasSubjectAreahas subject areaInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcePositionvivo:positionInOrganizationposition in organizationrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD000951Chemicals & Drugs1073240.840388Antigens, NeoplasmD001854Anatomy1202530.89941Bone Marrow CellsD003594Anatomy37940.960687Cytoplasmic GranulesD005089Physiology431080.951164ExocytosisD002857Chemicals & Drugs16170.990972ChromiumD004533Chemicals & Drugs26340.992746Egtazic AcidD004305Concepts & Ideas52019580.724084Dose-Response Relationship, DrugD007167Procedures1836270.665954ImmunotherapyD004797Procedures2173760.903442Enzyme-Linked Immunosorbent AssayD005434Procedures2836790.849112Flow CytometryD005805Genes & Molecular Sequences24480.975321Genes, MHC Class ID008562Chemicals & Drugs1894280.823137Membrane GlycoproteinsAuthorship 259664D007371Chemicals & Drugs1554440.841977Interferon-gammaD006801Living Beings2262862810.130052HumansD020133Procedures3498770.836853Reverse Transcriptase Polymerase Chain Reaction0.06513990.06513991authors10.2528has subject areaD008223Disorders1142620.859106LymphomaD009101Disorders823070.737421Multiple MyelomaD016896Concepts & Ideas101179490.402389Treatment OutcomeD025721Chemicals & Drugs16190.991273WT1 ProteinsD012333Chemicals & Drugs51619750.640012RNA, MessengerD013602Anatomy783140.879073T-Lymphocytes, CytotoxicD045744Anatomy46824210.643233Cell Line, TumorD052899Chemicals & Drugs19540.978747Pore Forming Cytotoxic ProteinsD054353Chemicals & Drugs15550.974777PerforinD002118Chemicals & Drugs28211480.692432CalciumD002460Anatomy54024660.697085Cell LineD010455Chemicals & Drugs2456390.756113PeptidesD018942Chemicals & Drugs25310.985114MacrolidesUniversity of ChicagoChristopherFroelichChristopher Froelich41.78927490000000-87.601250000000001210Froelich, Christophertrue1