15467831Bernal-Mizrachi E, Fatrai S, Johnson JD, Ohsugi M, Otani K, Han Z, Polonsky KS, Permutt MAThe Journal of clinical investigationDiabetes Mellitus, Experimental; Insulin; Islets of Langerhans; Protein Serine-Threonine Kinases; Proto-Oncogene ProteinsAnimals; Apoptosis; Blood Glucose; Body Weight; Calcium; Culture Techniques; Dietary Fats; Disease Susceptibility; Gene Expression Regulation; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Protein Isoforms; Proto-Oncogene Proteins c-akt; Signal TransductionDefective insulin secretion and increased susceptibility to experimental diabetes are induced by reduced Akt activity in pancreatic islet beta cells. J Clin Invest. 2004 Oct; 114(7):928-36.J Clin Invest2004-10-01T00:00:002004Defective insulin secretion and increased susceptibility to experimental diabetes are induced by reduced Akt activity in pancreatic islet beta cells.prns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD000818Living Beings1457265180.249624AnimalsD003921Disorders611900.900961Diabetes Mellitus, ExperimentalD001786Chemicals & Drugs1948730.721653Blood GlucoseD001835Concepts & IdeasPhysiology2064590.877214Body WeightD007328Chemicals & Drugs22111590.666128InsulinD004198Concepts & IdeasPhysiology1091920.915972Disease SusceptibilityD005786Physiology51419170.529599Gene Expression RegulationD008810Living Beings55730870.60566Mice, Inbred C57BLAuthorship 257237D011518Chemicals & Drugs2306450.750392Proto-Oncogene ProteinsD007333Disorders1073770.808401Insulin ResistanceD007515Anatomy785440.752835Islets of LangerhansD008297Physiology1931408600.201617Male0.06475780.06475781authors10.2521has subject areaD017209Physiology41016780.608637ApoptosisD018345Living Beings43819180.695188Mice, KnockoutD051379Living Beings980113130.368397MiceD046508Procedures59910.989101Culture TechniquesD002118Chemicals & Drugs28211480.692432CalciumD004041Chemicals & DrugsObjects621340.923395Dietary FatsD015398Physiology69932330.460036Signal TransductionD020033Chemicals & Drugs1812690.909625Protein IsoformsD051057Chemicals & Drugs1483210.870521Proto-Oncogene Proteins c-aktUniversity of ChicagoKenneth S.PolonskyKenneth S. Polonsky41.78927490000000-87.601250000000002326Polonsky, Kenneth S.Professortrue1ProfessorProfessorMedicine-Endocrinology