19010906Fels DR, Ye J, Segan AT, Kridel SJ, Spiotto M, Olson M, Koong AC, Koumenis CCancer researchAntineoplastic Agents; Boronic Acids; Endoplasmic Reticulum; Protease Inhibitors; Pyrazines; Stress, PhysiologicalActivating Transcription Factor 4; Apoptosis; Autophagy; Bortezomib; Cell Hypoxia; Cell Line, Tumor; DNA-Binding Proteins; Humans; Microtubule-Associated Proteins; Necrosis; Protein Folding; Regulatory Factor X Transcription Factors; Signal Transduction; Thapsigargin; Transcription FactorsPreferential cytotoxicity of bortezomib toward hypoxic tumor cells via overactivation of endoplasmic reticulum stress pathways. Cancer Res. 2008 Nov 15; 68(22):9323-30.Cancer Res2008-11-15T00:00:002008Preferential cytotoxicity of bortezomib toward hypoxic tumor cells via overactivation of endoplasmic reticulum stress pathways.prns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAuthorshipvivo:hasSubjectAreahas subject areaInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkedInformationResourcelinked information resourcerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptD001343Physiology761480.857271AutophagyD000970Chemicals & Drugs40723510.435461Antineoplastic AgentsD001897Chemicals & Drugs28540.97053Boronic AcidsD004268Chemicals & Drugs35612080.630083DNA-Binding ProteinsD004721Anatomy1032500.866987Endoplasmic ReticulumD008869Chemicals & Drugs751760.897672Microtubule-Associated ProteinsD009336Disorders1362040.943338NecrosisD013312Physiology1502260.854218Stress, PhysiologicalD011480Chemicals & Drugs51720.962356Protease InhibitorsD011719Chemicals & Drugs39840.950276PyrazinesD014157Chemicals & Drugs40615550.562899Transcription FactorsAuthorship 36620D006801Living Beings2262862810.130052Humans0.1723630.1723631authors10.2521has subject areaD017209Physiology41016780.608637ApoptosisD019284Chemicals & Drugs30550.989347ThapsigarginD017510Physiology902800.84624Protein FoldingD015687Physiology671640.920544Cell HypoxiaD051701Chemicals & Drugs15150.988832Activating Transcription Factor 4D045744Anatomy46824210.643233Cell Line, TumorD00006928630750.970216BortezomibD00007170110110.997267Regulatory Factor X Transcription FactorsD015398Physiology69932330.460036Signal Transduction