B-cells and IL-4 promote methylcholanthrene-induced carcinogenesis but there is no evidence for a role of T/NKT-cells and their effector molecules (Fas-ligand, TNF-a, perforin).

B-cells and IL-4 promote methylcholanthrene-induced carcinogenesis but there is no evidence for a role of T/NKT-cells and their effector molecules (Fas-ligand, TNF-a, perforin). Int J Cancer. 2012 Oct 01; 131(7):1499-508.

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subject areas

Animals
B-Lymphocytes
Cell Transformation, Neoplastic
Environment
Fas Ligand Protein
Female
Interferon-gamma
Interleukin-4
Male
Methylcholanthrene
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Knockout
Mice, Nude
Natural Killer T-Cells
Perforin
T-Lymphocytes
Tumor Necrosis Factor-alpha