34232919Huang L, Zhao L, Zhang J, He F, Wang H, Liu Q, Shi D, Ni N, Wagstaff W, Chen C, Reid RR, Haydon RC, Luu HH, Shen L, He TC, Tang LAgingAntinematodal Agents; Antineoplastic Agents; Carcinoma, Ovarian Epithelial; Cisplatin; Drug Resistance, Neoplasm; Mebendazole; Ovarian Neoplasms; Signal TransductionAnimals; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Repositioning; Female; Humans; Mice; Mice, Nude; Tumor Stem Cell Assay; Wound Healing; Xenograft Model Antitumor AssaysAntiparasitic mebendazole (MBZ) effectively overcomes cisplatin resistance in human ovarian cancer cells by inhibiting multiple cancer-associated signaling pathways. Aging (Albany NY). 2021 07 07; 13(13):17407-17427.Aging (Albany NY)2021-07-07T00:00:002021Antiparasitic mebendazole (MBZ) effectively overcomes cisplatin resistance in human ovarian cancer cells by inhibiting multiple cancer-associated signaling pathways.prns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD000970Chemicals & Drugs40723510.435461Antineoplastic AgentsD000818Living Beings1457265180.249624AnimalsD000969Chemicals & Drugs570.993837Antinematodal AgentsD002465Physiology2507560.750985Cell MovementD002945Chemicals & Drugs1296120.82183CisplatinSurgery-General SurgeryD008463Chemicals & Drugs460.994646MebendazoleD008819Living Beings2217900.84759Mice, NudeD010051Disorders1667380.613506Ovarian NeoplasmsD005260Physiology1992444050.191167FemaleD006801Living Beings2262862810.130052HumansD014410Procedures25350.994309Tumor Stem Cell AssayD019008Physiology1805890.751116Drug Resistance, NeoplasmOrthopedic Surgery and Rehabilitation MedicineD017209Physiology41016780.608637ApoptosisAuthorship 14775412Authorship 147755150.2069830.2069833authors10.2520has subject areaD049109Physiology43515710.639735Cell ProliferationAuthorship 15131514D051379Living Beings980113130.368397MiceD014945Physiology1643420.824933Wound HealingD023041Procedures1684580.868544Xenograft Model Antitumor AssaysD045744Anatomy46824210.643233Cell Line, TumorD058492Procedures16220.978372Drug Repositioninghttp://www.boneandcancer.orgLab homepagehttps://ortho.uchicago.edu/p-Haydon.phpDepartment of Orthopaedic Surgery and Rehabilitation Medicinehttps://scholar.google.com/citations?user=YRifvyAAAAAJ&hl=enGoogle ScholarD015398Physiology69932330.460036Signal TransductionUniversity of ChicagoRex C.HaydonRex C. Haydon41.78927490000000-87.60125000000000395Haydon, Rex C.ProfessorLeShenLe Shen41.78927490000000-87.60125000000000411Shen, LeResearch Associate ProfessorTong-ChuanHew2FhDoEXCuiXhHlsaUXv9Gq0+s+oTong-Chuan He41.78927490000000-87.60125000000000550He, Tong-ChuanAssociate Professortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1Research Associate ProfessorResearch Associate Professor