34263728Richter WF, Shah RN, Ruthenburg AJeLifefms-Like Tyrosine Kinase 3; Gene Rearrangement; Histones; Leukemia; Myeloid-Lymphoid Leukemia ProteinEnzyme Inhibitors; Gene Expression Regulation, Leukemic; Histone-Lysine N-Methyltransferase; Homeodomain Proteins; Humans; Methylation; Myeloid Ecotropic Viral Integration Site 1 Protein; STAT5 Transcription Factor; Tumor Suppressor ProteinsNon-canonical H3K79me2-dependent pathways promote the survival of MLL-rearranged leukemia. Elife. 2021 07 15; 10.Elife2021-07-15T00:00:002021Non-canonical H3K79me2-dependent pathways promote the survival of MLL-rearranged leukemia.prns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD004791Chemicals & Drugs2686320.779731Enzyme InhibitorsD007938Disorders1023180.828811LeukemiaMolecular Genetics and Cell BiologyD006657Chemicals & Drugs1523090.838801HistonesD006801Living Beings2262862810.130052HumansD015321Physiology861700.916065Gene RearrangementD008745Phenomena932510.912297MethylationAuthorship 14798130.829190.829191authors10.2514has subject areaD015973Physiology36900.948118Gene Expression Regulation, LeukemicD018398Chemicals & Drugs1905350.737984Homeodomain ProteinsD025521Chemicals & Drugs1482790.844953Tumor Suppressor ProteinsD050799Chemicals & Drugs25420.984797STAT5 Transcription FactorD051788Chemicals & Drugs20720.965831Myeloid-Lymphoid Leukemia ProteinD051941Chemicals & Drugs431210.931518fms-Like Tyrosine Kinase 3D00007506413200.993004Myeloid Ecotropic Viral Integration Site 1 Proteinhttp://www.ruthenlab.orgruthenlab.orgD011495Chemicals & Drugs521540.903169Histone-Lysine N-MethyltransferaseUniversity of ChicagoAlexander J.Ruthenburg1nB8H6kQF+7Mg31EdUXm+mb7+MTz7LFLAlexander J. Ruthenburg41.78927490000000-87.601250000000001716Ruthenburg, Alexander J.Associate Professortrue1Associate ProfessorAssociate Professor