22034008McDonald DA, Shi C, Shenkar R, Stockton RA, Liu F, Ginsberg MH, Marchuk DA, Awad IAStroke1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Enzyme Inhibitors; Intracranial Arteriovenous Malformations; Vasodilator AgentsAnimals; Brain; Cerebral Hemorrhage; Inflammation; KRIT1 Protein; Mice; Mice, Knockout; Microtubule-Associated Proteins; MutS Homolog 2 Protein; Phenotype; Proto-Oncogene Proteins; rho-Associated Kinases; Tumor Suppressor Protein p53Fasudil decreases lesion burden in a murine model of cerebral cavernous malformation disease. Stroke. 2012 Feb; 43(2):571-4.Stroke2011-10-27T00:00:002011Fasudil decreases lesion burden in a murine model of cerebral cavernous malformation disease.prns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD000818Living Beings1457265180.249624AnimalsD001921Anatomy49222110.472349BrainD002543Disorders723250.776618Cerebral HemorrhageD004791Chemicals & Drugs2686320.779731Enzyme InhibitorsAuthorship 108263D008869Chemicals & Drugs751760.897672Microtubule-Associated ProteinsD007249Disorders3889130.65692InflammationD011518Chemicals & Drugs2306450.750392Proto-Oncogene ProteinsAuthorship 466148Authorship 466153Authorship 46613D014665Chemicals & Drugs741520.924215Vasodilator AgentsNeurological SurgeryD018345Living Beings43819180.695188Mice, Knockout0.4228190.1057054authors10.2517has subject areaD051379Living Beings980113130.368397MiceD051718Chemicals & Drugs22300.981895MutS Homolog 2 ProteinD054460Chemicals & Drugs401590.883845rho-Associated KinasesD002538Disorders181040.925744Intracranial Arteriovenous MalformationsD00007592711620.976628KRIT1 Proteinhttp://surgeryresearch.uchicago.edu/robert-shenkarRobert Shenkar, PhDD010641Physiology64723750.615854PhenotypeD016159Chemicals & Drugs1783800.816799Tumor Suppressor Protein p53D019307Chemicals & Drugs11360.9790811-(5-Isoquinolinesulfonyl)-2-MethylpiperazineUniversity of ChicagoIssamAwad3mN+CqU1DO/RmHllZ0mg9mHvIssam Awad41.78927490000000-87.60125000000000867Awad, IssamProfessorRobertShenkarRobert Shenkar41.78927490000000-87.60125000000000963Shenkar, RobertResearch Associate Professortrue1ProfessorProfessortrue1Research Associate ProfessorResearch Associate Professor