22723704Zhang X, Garbett K, Veeraraghavalu K, Wilburn B, Gilmore R, Mirnics K, Sisodia SSThe Journal of neuroscience : the official journal of the Society for NeuroscienceAutophagy; Lysosomes; Presenilin-1; Presenilin-2; PresenilinsAnimals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Blastocyst; Blotting, Western; Cathepsin D; Cell Line, Tumor; Cells, Cultured; DNA Primers; Gene Expression; Humans; Hydrogen-Ion Concentration; Mice; Mice, Knockout; Neurons; Polymerase Chain Reaction; RNA; RNA, Small Interfering; Vacuolar Proton-Translocating ATPasesA role for presenilins in autophagy revisited: normal acidification of lysosomes in cells lacking PSEN1 and PSEN2. J Neurosci. 2012 Jun 20; 32(25):8633-48.J Neurosci2012-06-20T00:00:002012A role for presenilins in autophagy revisited: normal acidification of lysosomes in cells lacking PSEN1 and PSEN2.prns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD001343Physiology761480.857271AutophagyD000818Living Beings1457265180.249624AnimalsD001755Anatomy21330.990225BlastocystD002402Chemicals & Drugs550.996616Cathepsin DNeurobiologyD006863Concepts & Ideas1974930.898048Hydrogen-Ion ConcentrationD009474Anatomy29515450.526388NeuronsD012313Chemicals & Drugs2195600.726603RNAD006801Living Beings2262862810.130052HumansAuthorship 487817Authorship 487823D008247Anatomy581040.930298LysosomesD025262Chemicals & Drugs16190.987407Vacuolar Proton-Translocating ATPasesD015870Physiology47612810.710433Gene ExpressionD018345Living Beings43819180.695188Mice, Knockout0.442270.1105672authors10.2523has subject areaD051379Living Beings980113130.368397MiceD053763Chemicals & Drugs360.99231PresenilinsD053766Chemicals & Drugs7250.993028Presenilin-2D051778Chemicals & Drugs35540.968552Basic Helix-Loop-Helix Leucine Zipper Transcription FactorsD015153PhenomenaProcedures3187810.86116Blotting, WesternD016133Procedures3549270.826552Polymerase Chain ReactionD053764Chemicals & Drugs151000.95726Presenilin-1D034741Chemicals & Drugs2335470.850016RNA, Small InterferingD045744Anatomy46824210.643233Cell Line, TumorD002478Anatomy60328100.667881Cells, Culturedhttp://voices.uchicago.edu/drsisodialab/Sisodia LabD017931Chemicals & Drugs2555420.907631DNA PrimersUniversity of ChicagoKarthikeyanVeeraraghavaluKarthikeyan Veeraraghavalu41.78927490000000-87.601250000000002265Veeraraghavalu, KarthikeyanSangram S.SisodiaxHF6ArIaHeX5hHlsaUXv9Gq0+s+oSangram S. Sisodia41.78927490000000-87.60125000000000510Sisodia, Sangram S.Professortrue1true1ProfessorProfessor