21060808Sun C, Southard C, Witonsky DB, Kittler R, Di Rienzo APLoS geneticsAdaptation, Physiological; Adaptor Proteins, Signal Transducing; Climate; Polymorphism, Single NucleotideAlleles; Benzoates; Binding Sites; Cell Line, Tumor; Chromatin Immunoprecipitation; Down-Regulation; Gene Frequency; Genetics, Population; Geography; Hep G2 Cells; Humans; Octamer Transcription Factor-1; Protein Binding; Regulatory-Associated Protein of mTOR; Retinoid X Receptors; Retinoids; Temperature; Tetrahydronaphthalenes; Time Factors; Transcription Initiation SiteAllele-specific down-regulation of RPTOR expression induced by retinoids contributes to climate adaptations. PLoS Genet. 2010 Oct 28; 6(10):e1001178.PLoS Genet2010-10-28T00:00:002010Allele-specific down-regulation of RPTOR expression induced by retinoids contributes to climate adaptations.plugins:FeaturedVideosFeatured Videosprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD000222Physiology1603060.815144Adaptation, PhysiologicalD000483Genes & Molecular Sequences29311270.757194AllelesD001565Chemicals & Drugs26440.976352BenzoatesD001665Chemicals & Drugs32910980.797809Binding SitesD005787Concepts & Ideas1706760.840385Gene FrequencyD005843Concepts & IdeasOccupations1082230.917289GeographyD005828Occupations973940.779923Genetics, PopulationD011485PhenomenaPhysiology42014540.739266Protein BindingAuthorship 430245D012176Chemicals & Drugs16170.993161RetinoidsAuthorship 430234Authorship 430251D006801Living Beings2262862810.130052HumansD013997Concepts & Ideas118351980.519628Time FactorsD024363Chemicals & Drugs37450.983779Transcription Initiation Site0.3945970.09864933authors10.2524has subject areaD050811Chemicals & Drugs15170.995018Octamer Transcription Factor-1D047369Procedures841330.95555Chromatin ImmunoprecipitationD047488Chemicals & Drugs20390.98713Retinoid X ReceptorsD048868Chemicals & Drugs1653020.849209Adaptor Proteins, Signal TransducingD013696Concepts & Ideas2043950.88309TemperatureD015536Physiology2565040.86254Down-RegulationD056945Anatomy35480.981957Hep G2 CellsD045744Anatomy46824210.643233Cell Line, TumorD002980Phenomena31500.96434ClimateD0000762239110.996948Regulatory-Associated Protein of mTORhttp://genapps.uchicago.edu/newlabweb/index.htmlLab web siteD013764Chemicals & Drugs14150.990917TetrahydronaphthalenesD020641Genes & Molecular Sequences32223500.535626Polymorphism, Single NucleotideHuman GeneticsUniversity of ChicagoChangSunChang Sun41.78927490000000-87.601250000000002024Sun, ChangRalfKittlerRalf Kittler41.78927490000000-87.60125000000000695Kittler, RalfAnnaDi RienzoAnna Di Rienzo41.78927490000000-87.60125000000000993Di Rienzo, AnnaProfessortrue1true1true1ProfessorProfessor