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Leukotriene B4 receptor antagonist LY293111 induces S-phase cell cycle arrest and apoptosis in human pancreatic cancer cells.
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Leukotriene B4 receptor antagonist LY293111 induces S-phase cell cycle arrest and apoptosis in human pancreatic cancer cells.
Leukotriene B4 receptor antagonist LY293111 induces S-phase cell cycle arrest and apoptosis in human pancreatic cancer cells. Anticancer Drugs. 2007 Jun; 18(5):535-41.
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PubMed
subject areas
Apoptosis
bcl-2-Associated X Protein
Benzoates
Blotting, Western
Caspase 3
Caspase 7
Caspase 9
Cell Cycle
Cell Line, Tumor
Cyclin A
Cyclin E
Cyclin-Dependent Kinase 2
Cyclin-Dependent Kinase Inhibitor p21
Cyclin-Dependent Kinase Inhibitor p27
Cytochromes c
Enzyme Activation
Flow Cytometry
Genes, bcl-2
Humans
Leukotriene Antagonists
Myeloid Cell Leukemia Sequence 1 Protein
Neoplasm Proteins
Pancreatic Neoplasms
Poly(ADP-ribose) Polymerase Inhibitors
Poly(ADP-ribose) Polymerases
Proto-Oncogene Proteins c-bcl-2
Receptors, Leukotriene B4
S Phase
authors with profiles
Mark Talamonti