D019895Chemicals & DrugsD08.811.739.500.667D08.811.913.696.445.8253210.985036Transposasesprns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonBiochemistry and Molecular Biology29294068Rasila TS, Pulkkinen E, Kiljunen S, Haapa-Paananen S, Pajunen MI, Salminen A, Paulin L, Vihinen M, Rice PA, Savilahti HNucleic acids researchMu transpososome activity-profiling yields hyperactive MuA variants for highly efficient genetic and genome engineering. Nucleic Acids Res. 2018 05 18; 46(9):4649-4661.Nucleic Acids Res2018-05-18T00:00:002018Mu transpososome activity-profiling yields hyperactive MuA variants for highly efficient genetic and genome engineering.FrancoisSpitz0XF5ArUPOfnamXNnYUHhvWD+6g==Francois Spitz41.7886000000000087.598699999999993775Spitz, FrancoisProfessor32499410Rice PA, Craig NL, Dyda FScience (New York, N.Y.)Comment on "RNA-guided DNA insertion with CRISPR-associated transposases". Science. 2020 06 05; 368(6495).Science2020-06-05T00:00:002020Comment on "RNA-guided DNA insertion with CRISPR-associated transposases".17785414Mizuuchi M, Rice PA, Wardle SJ, Haniford DB, Mizuuchi KProceedings of the National Academy of Sciences of the United States of AmericaControl of transposase activity within a transpososome by the configuration of the flanking DNA segment of the transposon. Proc Natl Acad Sci U S A. 2007 Sep 11; 104(37):14622-7.Proc Natl Acad Sci U S A2007-09-04T00:00:002007Control of transposase activity within a transpososome by the configuration of the flanking DNA segment of the transposon.2.904180.01147333research area of0.7678470.024916421subject area for23135398Montaño SP, Pigli YZ, Rice PANatureThe µ transpososome structure sheds light on DDE recombinase evolution. Nature. 2012 Nov 15; 491(7424):413-7.Nature2012-11-07T00:00:002012The µ transpososome structure sheds light on DDE recombinase evolution.http://voices.uchicago.edu/spitzlab/Spitzlab websitehttps://voices.uchicago.edu/phoebericelab/Rice Lab web siteHuman GeneticsPathologyUniversity of ChicagoPhoebe A.RicePhoebe A. Rice41.78927490000000-87.601250000000002362Rice, Phoebe A.ProfessorGodfreyGetzGodfrey S. Getz41.78927490000000-87.60125000000000725Getz, GodfreyEmeritus/Emerita, Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1Emeritus/Emerita, ProfessorEmeritus/Emerita, Professor28177285Fuller JR, Rice PAeLifeTarget DNA bending by the Mu transpososome promotes careful transposition and prevents its reversal. Elife. 2017 02 13; 6.Elife2017-02-13T00:00:002017Target DNA bending by the Mu transpososome promotes careful transposition and prevents its reversal.