22753902Mendler JH, Maharry K, Radmacher MD, Mrózek K, Becker H, Metzeler KH, Schwind S, Whitman SP, Khalife J, Kohlschmidt J, Nicolet D, Powell BL, Carter TH, Wetzler M, Moore JO, Kolitz JE, Baer MR, Carroll AJ, Larson RA, Caligiuri MA, Marcucci G, Bloomfield CDJournal of clinical oncology : official journal of the American Society of Clinical OncologyAntineoplastic Combined Chemotherapy Protocols; Core Binding Factor Alpha 2 Subunit; Cytogenetic Analysis; Gene Expression Profiling; Leukemia, Myeloid, Acute; MicroRNAs; MutationAdolescent; Adult; Age Factors; Aged; Aged, 80 and over; Disease Progression; Disease-Free Survival; DNA Mutational Analysis; Female; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Multivariate Analysis; Nucleophosmin; Oligonucleotide Array Sequence Analysis; Phenotype; Polymerase Chain Reaction; Proportional Hazards Models; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; United States; Young AdultRUNX1 mutations are associated with poor outcome in younger and older patients with cytogenetically normal acute myeloid leukemia and with distinct gene and MicroRNA expression signatures. J Clin Oncol. 2012 Sep 01; 30(25):3109-18.J Clin Oncol2012-07-02T00:00:002012RUNX1 mutations are associated with poor outcome in younger and older patients with cytogenetically normal acute myeloid leukemia and with distinct gene and MicroRNA expression signatures.prns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD000367Concepts & Ideas62718420.694019Age FactorsD000369Living Beings93664810.461294Aged, 80 and overD000293Living Beings111389680.400538AdolescentD000368Living Beings1341183530.294764AgedD000328Living Beings1578255770.254432AdultD000971Procedures30624340.476235Antineoplastic Combined Chemotherapy ProtocolsD004252Procedures2265260.864587DNA Mutational AnalysisD008875Concepts & IdeasLiving Beings1473249570.258811Middle AgedD009154Physiology70239520.442648MutationD005260Physiology1992444050.191167FemaleD012307Concepts & Ideas94153970.464223Risk FactorsAuthorship 4886418D006801Living Beings2262862810.130052HumansD013997Concepts & Ideas118351980.519628Time FactorsD014481Geographic Areas102566370.406601United StatesD008297Physiology1931408600.201617MaleD016016Concepts & Ideas3048570.817586Proportional Hazards ModelsD018570Concepts & IdeasProcedures62722530.57096Risk AssessmentMedicine-Hematology and OncologyD015470Disorders1227550.629242Leukemia, Myeloid, AcuteD016896Concepts & Ideas101179490.402389Treatment OutcomeD018450Physiology49815310.700842Disease Progression0.1108190.1108191authors10.2534has subject areaD020411DevicesProcedures2526890.819693Oligonucleotide Array Sequence AnalysisD020869Procedures44213810.644605Gene Expression ProfilingD015999Concepts & Ideas4199970.796631Multivariate AnalysisD016015Concepts & IdeasProcedures44611840.742875Logistic ModelsD016133Procedures3549270.826552Polymerase Chain ReactionD050676Chemicals & Drugs21520.97529Core Binding Factor Alpha 2 SubunitD053208Concepts & Ideas3258590.818599Kaplan-Meier EstimateD010641Physiology64723750.615854PhenotypeD015972Physiology31511960.666181Gene Expression Regulation, NeoplasticD018572Concepts & Ideas25812030.792696Disease-Free SurvivalD020022Physiology39922670.521961Genetic Predisposition to DiseaseD020732Procedures37710.978916Cytogenetic AnalysisD035683Chemicals & Drugs2225340.684235MicroRNAsD055815Living Beings97159610.423207Young AdultUniversity of ChicagoRichard A.LarsonRichard A. Larson41.78927490000000-87.601250000000001169Larson, Richard A.Professortrue1ProfessorProfessor