D044763Chemicals & DrugsD08.811.464.938.50013300.985816Ubiquitin-Conjugating Enzymesprns:emailEncryptedemail addressFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonBiochemistry and Molecular BiologyAntonioBiancoAntonio Bianco41.7886000000000087.598699999999993717Bianco, AntonioProfessorEnginOzkanEngin Ozkan0.000000000000000.000000000000002877Ozkan, EnginAssociate Professor18497339Suryavathi V, Khattri A, Gopal K, Rani DS, Panneerdoss S, Gupta NJ, Chakravarty B, Deenadayal M, Singh L, Thangaraj KJournal of andrologyNovel variants in UBE2B gene and idiopathic male infertility. J Androl. 2008 Sep-Oct; 29(5):564-71.J Androl2008-05-22T00:00:002008Novel variants in UBE2B gene and idiopathic male infertility.20818381Yamauchi T, Hara K, Maeda S, Yasuda K, Takahashi A, Horikoshi M, Nakamura M, Fujita H, Grarup N, Cauchi S, Ng DP, Ma RC, Tsunoda T, Kubo M, Watada H, Maegawa H, Okada-Iwabu M, Iwabu M, Shojima N, Shin HD, Andersen G, Witte DR, Jørgensen T, Lauritzen T, Sandbæk A, Hansen T, Ohshige T, Omori S, Saito I, Kaku K, Hirose H, So WY, Beury D, Chan JC, Park KS, Tai ES, Ito C, Tanaka Y, Kashiwagi A, Kawamori R, Kasuga M, Froguel P, Pedersen O, Kamatani N, Nakamura Y, Kadowaki TNature geneticsA genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B. Nat Genet. 2010 Oct; 42(10):864-8.Nat Genet2010-09-05T00:00:002010A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.22045845Agik S, Franek BS, Kumar AA, Kumabe M, Utset TO, Mikolaitis RA, Jolly M, Niewold TBThe Journal of rheumatologyThe autoimmune disease risk allele of UBE2L3 in African American patients with systemic lupus erythematosus: a recessive effect upon subphenotypes. J Rheumatol. 2012 Jan; 39(1):73-8.J Rheumatol2011-11-01T00:00:002011The autoimmune disease risk allele of UBE2L3 in African American patients with systemic lupus erythematosus: a recessive effect upon subphenotypes.0.5936950.011787113research area of0.4901820.02666834subject area forhttp://www.BiancoLab.orgMy Lab Sitehttps://voices.uchicago.edu/ozkanlabThe Özkan Lab at the University of ChicagoBSD MicrobiologyUniversity of ChicagoBernardRoizman1Wd7BaAHHaLLnnN+bUfg02fp+4Wo6r1Xc3h9eaOOFmI=Bernard Roizman41.78927490000000-87.601250000000001112Roizman, BernardEmeritus/Emerita, ProfessorMichaelEllisonMichael Ellison41.78927490000000-87.601250000000001270Ellison, MichaelBrianKimBrian Kim41.7886000000000087.598699999999994499Kim, BrianAssociate Professortrue1true1Associate ProfessorAssociate Professortrue1Emeritus/Emerita, ProfessorEmeritus/Emerita, Professortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessor1010Medicine-Endocrinology19887602Ueki T, Park JH, Nishidate T, Kijima K, Hirata K, Nakamura Y, Katagiri TCancer researchUbiquitination and downregulation of BRCA1 by ubiquitin-conjugating enzyme E2T overexpression in human breast cancer cells. Cancer Res. 2009 Nov 15; 69(22):8752-60.Cancer Res2009-11-03T00:00:002009Ubiquitination and downregulation of BRCA1 by ubiquitin-conjugating enzyme E2T overexpression in human breast cancer cells.24316736Huang H, Ceccarelli DF, Orlicky S, St-Cyr DJ, Ziemba A, Garg P, Plamondon S, Auer M, Sidhu S, Marinier A, Kleiger G, Tyers M, Sicheri FNature chemical biologyE2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin. Nat Chem Biol. 2014 Feb; 10(2):156-163.Nat Chem Biol2013-12-15T00:00:002013E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin.