D051356Chemicals & DrugsD05.750.078.730.281D12.644.360.024.280D12.776.157.057.014D12.776.220.525.281D12.776.476.024.311D12.776.744.39011110.986834Cortactinprns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonPhysicsMargaretGardelMargaret L. Gardel41.7886000000000087.598699999999993493Gardel, MargaretProfessor29535305Nekrasova O, Harmon RM, Broussard JA, Koetsier JL, Godsel LM, Fitz GN, Gardel ML, Green KJNature communicationsDesmosomal cadherin association with Tctex-1 and cortactin-Arp2/3 drives perijunctional actin polymerization to promote keratinocyte delamination. Nat Commun. 2018 03 13; 9(1):1053.Nat Commun2018-03-13T00:00:002018Desmosomal cadherin association with Tctex-1 and cortactin-Arp2/3 drives perijunctional actin polymerization to promote keratinocyte delamination.Medicine-Hematology and Oncology22219181Usatyuk PV, Singleton PA, Pendyala S, Kalari SK, He D, Gorshkova IA, Camp SM, Moitra J, Dudek SM, Garcia JG, Natarajan VThe Journal of biological chemistryNovel role for non-muscle myosin light chain kinase (MLCK) in hyperoxia-induced recruitment of cytoskeletal proteins, NADPH oxidase activation, and reactive oxygen species generation in lung endothelium. J Biol Chem. 2012 Mar 16; 287(12):9360-75.J Biol Chem2012-01-04T00:00:002012Novel role for non-muscle myosin light chain kinase (MLCK) in hyperoxia-induced recruitment of cytoskeletal proteins, NADPH oxidase activation, and reactive oxygen species generation in lung endothelium.26385474Stamatovic SM, Sladojevic N, Keep RF, Andjelkovic AVActa neuropathologicaPDCD10 (CCM3) regulates brain endothelial barrier integrity in cerebral cavernous malformation type 3: role of CCM3-ERK1/2-cortactin cross-talk. Acta Neuropathol. 2015 Nov; 130(5):731-50.Acta Neuropathol2015-09-18T00:00:002015PDCD10 (CCM3) regulates brain endothelial barrier integrity in cerebral cavernous malformation type 3: role of CCM3-ERK1/2-cortactin cross-talk.0.8776270.077966811research area of0.8893360.054435217subject area for35856787Mascarenhas JB, Song JH, Gaber AA, Jacobson JR, Cress AE, Camp SM, Dudek SM, Garcia JGNCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyAn Actin-, Cortactin- and Ena-VASP-Linked Complex Contributes to Endothelial Cell Focal Adhesion and Vascular Barrier Regulation. Cell Physiol Biochem. 2022 Jul 20; 56(4):329-339.Cell Physiol Biochem2022-07-20T00:00:002022An Actin-, Cortactin- and Ena-VASP-Linked Complex Contributes to Endothelial Cell Focal Adhesion and Vascular Barrier Regulation.http://www.pgrn.org/pgx-of-chemotherapeutic-toxicities.htmlMy Lab ObjectivesMedicineUniversity of ChicagoMary EileenDolan2mdtBK0UF8zMknJtY0fp/Cv/+94=Mary Eileen Dolan41.78927490000000-87.601250000000002594Dolan, Mary EileenProfessorPanfengFuPanfeng Fu41.78927490000000-87.601250000000002643Fu, PanfengJosephMascarenhasJoseph Mascarenhas41.78927490000000-87.601250000000002655Mascarenhas, JosephYujiaWenYujia Wen41.78927490000000-87.60125000000000845Wen, YujiaPostdoctoral Scholartrue1true1true1Postdoctoral ScholarPostdoctoral Scholartrue1ProfessorProfessortrue1ProfessorProfessor25022754Tian Y, Tian X, Gawlak G, O'Donnell JJ, Sacks DB, Birukova AAMolecular and cellular biologyIQGAP1 regulates endothelial barrier function via EB1-cortactin cross talk. Mol Cell Biol. 2014 Sep 15; 34(18):3546-58.Mol Cell Biol2014-07-14T00:00:002014IQGAP1 regulates endothelial barrier function via EB1-cortactin cross talk.