D051541Chemicals & DrugsD12.776.260.262.750D12.776.260.950.249.500D12.776.660.352.750D12.776.930.318.750D12.776.930.977.249.500580.996367Hepatocyte Nuclear Factor 3-alphaprns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson27257062Yang YA, Zhao JC, Fong KW, Kim J, Li S, Song C, Song B, Zheng B, He C, Yu JNucleic acids researchFOXA1 potentiates lineage-specific enhancer activation through modulating TET1 expression and function. Nucleic Acids Res. 2016 09 30; 44(17):8153-64.Nucleic Acids Res2016-06-01T00:00:002016FOXA1 potentiates lineage-specific enhancer activation through modulating TET1 expression and function.31644911Cocce KJ, Jasper JS, Desautels TK, Everett L, Wardell S, Westerling T, Baldi R, Wright TM, Tavares K, Yllanes A, Bae Y, Blitzer JT, Logsdon C, Rakiec DP, Ruddy DA, Jiang T, Broadwater G, Hyslop T, Hall A, Laine M, Phung L, Greene GL, Martin LA, Pancholi S, Dowsett M, Detre S, Marks JR, Crawford GE, Brown M, Norris JD, Chang CY, McDonnell DPCell reportsThe Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer. Cell Rep. 2019 10 22; 29(4):889-903.e10.Cell Rep2019-10-22T00:00:002019The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer.RaghuMirmiraRaghu Mirmira41.7886000000000087.598699999999993890Mirmira, RaghuProfessor32512502Hight SK, Mootz A, Kollipara RK, McMillan E, Yenerall P, Otaki Y, Li LS, Avila K, Peyton M, Rodriguez-Canales J, Mino B, Villalobos P, Girard L, Dospoy P, Larsen J, White MA, Heymach JV, Wistuba II, Kittler R, Minna JDNeoplasia (New York, N.Y.)An in vivo functional genomics screen of nuclear receptors and their co-regulators identifies FOXA1 as an essential gene in lung tumorigenesis. Neoplasia. 2020 08; 22(8):294-310.Neoplasia2020-05-13T00:00:002020An in vivo functional genomics screen of nuclear receptors and their co-regulators identifies FOXA1 as an essential gene in lung tumorigenesis.Ben May Department of Cancer Research22590586DeGraff DJ, Clark PE, Cates JM, Yamashita H, Robinson VL, Yu X, Smolkin ME, Chang SS, Cookson MS, Herrick MK, Shariat SF, Steinberg GD, Frierson HF, Wu XR, Theodorescu D, Matusik RJPloS oneLoss of the urothelial differentiation marker FOXA1 is associated with high grade, late stage bladder cancer and increased tumor proliferation. PLoS One. 2012; 7(5):e36669.PLoS One2012-05-10T00:00:002012Loss of the urothelial differentiation marker FOXA1 is associated with high grade, late stage bladder cancer and increased tumor proliferation.0.1967250.01272665research area of0.7645030.05109210subject area forChuanHe1Gp8Cq8dHMzMknJtY0fp/Cv/+94=Chuan He0.000000000000000.000000000000003123He, ChuanProfessorhttps://benmay.uchicago.eduBen May Department web sitehttp://he-group.uchicago.eduMy Lab SiteChemistryUniversity of ChicagoCancer BiologySimonHaywardSimon Hayward41.7886000000000087.598699999999994469Hayward, SimonJean Ruggles Romoser Chair of Cancer Research24840332DeGraff DJ, Grabowska MM, Case TC, Yu X, Herrick MK, Hayward WJ, Strand DW, Cates JM, Hayward SW, Gao N, Walter MA, Buttyan R, Yi Y, Kaestner KH, Matusik RJLaboratory investigation; a journal of technical methods and pathologyFOXA1 deletion in luminal epithelium causes prostatic hyperplasia and alteration of differentiated phenotype. Lab Invest. 2014 Jul; 94(7):726-39.Lab Invest2014-05-19T00:00:002014FOXA1 deletion in luminal epithelium causes prostatic hyperplasia and alteration of differentiated phenotype.RalfKittlerRalf Kittler41.78927490000000-87.60125000000000695Kittler, RalfGeoffreyGreene0GV7DqQbHMzMknJtY0fp/Cv/+94=Geoffrey Greene41.78927490000000-87.60125000000000901Greene, GeoffreyProfessortrue1true1ProfessorProfessortrue1Jean Ruggles Romoser Chair of Cancer ResearchJean Ruggles Romoser Chair of Cancer Researchtrue1ProfessorProfessortrue1ProfessorProfessorMedicine-Endocrinology