D051638Chemicals & DrugsD12.776.157.530.400.600.900.249D12.776.543.550.450.750.900.249D12.776.543.585.400.750.900.24912260.97748Ether-A-Go-Go Potassium Channelsplugins:FeaturedVideosFeatured Videosprns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson31017964Vaddi DR, Piao L, Khan SA, Wang N, Prabhakar NR, Nanduri JPloS oneHypoxia induced hERG trafficking defect linked to cell cycle arrest in SH-SY5Y cells. PLoS One. 2019; 14(4):e0215905.PLoS One2019-04-24T00:00:002019Hypoxia induced hERG trafficking defect linked to cell cycle arrest in SH-SY5Y cells.SunhwanJoSunhwan Jo0.000000000000000.000000000000003046Jo, SunhwanPost Doctoral Scholar19654002Nanduri J, Bergson P, Wang N, Ficker E, Prabhakar NRBiochemical and biophysical research communicationsHypoxia inhibits maturation and trafficking of hERG K(+) channel protein: Role of Hsp90 and ROS. Biochem Biophys Res Commun. 2009 Oct 16; 388(2):212-6.Biochem Biophys Res Commun2009-08-03T00:00:002009Hypoxia inhibits maturation and trafficking of hERG K(+) channel protein: Role of Hsp90 and ROS.21908602Ferrer T, Cordero-Morales JF, Arias M, Ficker E, Medovoy D, Perozo E, Tristani-Firouzi MThe Journal of biological chemistryMolecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K+ channel inactivation pathway. J Biol Chem. 2011 Nov 11; 286(45):39091-9.J Biol Chem2011-09-09T00:00:002011Molecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K+ channel inactivation pathway.20712994Rodriguez N, Amarouch MY, Montnach J, Piron J, Labro AJ, Charpentier F, Mérot J, Baró I, Loussouarn GBiophysical journalPhosphatidylinositol-4,5-bisphosphate (PIP(2)) stabilizes the open pore conformation of the Kv11.1 (hERG) channel. Biophys J. 2010 Aug 09; 99(4):1110-8.Biophys J2010-08-09T00:00:002010Phosphatidylinositol-4,5-bisphosphate (PIP(2)) stabilizes the open pore conformation of the Kv11.1 (hERG) channel.1.925660.014052312research area of0.7105030.046581719subject area forhttps://integrativephysiology.uchicago.edu/Institute for Integrative Physiology and Center for Systems Biology of Oxygen SensingBiochem/Mol BioUniversity of ChicagoAlainLabroAlain J. Labro41.78927490000000-87.601250000000001296Labro, AlainNanduri R.Prabhakar2WNnD7QHEMzMknJtY0fp/Cv/+94=Nanduri R. Prabhakar41.78927490000000-87.601250000000001680Prabhakar, Nanduri R.ProfessorLinPiaoLin Piao41.78927490000000-87.601250000000001820Piao, LinJayasriNanduriJayasri Nanduri41.78927490000000-87.601250000000002544Nanduri, JayasriResearch Professortrue1true1true1Post Doctoral ScholarPost Doctoral Scholartrue1ProfessorProfessortrue1Research ProfessorResearch ProfessorMedicine-Emergency Medicine26659724Wang N, Kang HS, Ahmmed G, Khan SA, Makarenko VV, Prabhakar NR, Nanduri JAmerican journal of physiology. Cell physiologyCalpain activation by ROS mediates human ether-a-go-go-related gene protein degradation by intermittent hypoxia. Am J Physiol Cell Physiol. 2016 Mar 01; 310(5):C329-36.Am J Physiol Cell Physiol2015-12-09T00:00:002015Calpain activation by ROS mediates human ether-a-go-go-related gene protein degradation by intermittent hypoxia.