D019893Chemicals & DrugsD08.811.913.696.620.682.700.862D12.644.360.600D12.776.476.6009100.996916Ribosomal Protein S6 Kinasesplugins:FeaturedVideosFeatured Videosprns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson29059430Morton LM, Sampson JN, Armstrong GT, Chen TH, Hudson MM, Karlins E, Dagnall CL, Li SA, Wilson CL, Srivastava DK, Liu W, Kang G, Oeffinger KC, Henderson TO, Moskowitz CS, Gibson TM, Merino DM, Wong JR, Hammond S, Neglia JP, Turcotte LM, Miller J, Bowen L, Wheeler WA, Leisenring WM, Whitton JA, Burdette L, Chung C, Hicks BD, Jones K, Machiela MJ, Vogt A, Wang Z, Yeager M, Neale G, Lear M, Strong LC, Yasui Y, Stovall M, Weathers RE, Smith SA, Howell R, Davies SM, Radloff GA, Onel K, Berrington de González A, Inskip PD, Rajaraman P, Fraumeni JF, Bhatia S, Chanock SJ, Tucker MA, Robison LLJournal of the National Cancer InstituteGenome-Wide Association Study to Identify Susceptibility Loci That Modify Radiation-Related Risk for Breast Cancer After Childhood Cancer. J Natl Cancer Inst. 2017 11 01; 109(11).J Natl Cancer Inst2017-11-01T00:00:002017Genome-Wide Association Study to Identify Susceptibility Loci That Modify Radiation-Related Risk for Breast Cancer After Childhood Cancer.RaghuMirmiraRaghu Mirmira41.7886000000000087.598699999999993890Mirmira, RaghuProfessor28699639Blandino-Rosano M, Barbaresso R, Jimenez-Palomares M, Bozadjieva N, Werneck-de-Castro JP, Hatanaka M, Mirmira RG, Sonenberg N, Liu M, Rüegg MA, Hall MN, Bernal-Mizrachi ENature communicationsLoss of mTORC1 signalling impairs ß-cell homeostasis and insulin processing. Nat Commun. 2017 07 12; 8:16014.Nat Commun2017-07-12T00:00:002017Loss of mTORC1 signalling impairs ß-cell homeostasis and insulin processing.11274216Dickson LM, Lingohr MK, McCuaig J, Hugl SR, Snow L, Kahn BB, Myers MG, Rhodes CJThe Journal of biological chemistryDifferential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1). J Biol Chem. 2001 Jun 15; 276(24):21110-20.J Biol Chem2001-03-27T00:00:002001Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1).18651560Yuan G, Nanduri J, Khan S, Semenza GL, Prabhakar NRJournal of cellular physiologyInduction of HIF-1alpha expression by intermittent hypoxia: involvement of NADPH oxidase, Ca2+ signaling, prolyl hydroxylases, and mTOR. J Cell Physiol. 2008 Dec; 217(3):674-85.J Cell Physiol2008-12-01T00:00:002008Induction of HIF-1alpha expression by intermittent hypoxia: involvement of NADPH oxidase, Ca2+ signaling, prolyl hydroxylases, and mTOR.0.2139230.007891819research area of0.6414210.03166499subject area forhttps://integrativephysiology.uchicago.edu/Institute for Integrative Physiology and Center for Systems Biology of Oxygen SensingNeurologyPediatricsUniversity of ChicagoRaymond P.RoosxXBmBLI1F+nMg3Vob0H3vWfp+4Wo6r1Xc3h9eaOOFmI=Raymond P. Roos41.78927490000000-87.601250000000001191Roos, Raymond P.ProfessorNanduri R.Prabhakar2WNnD7QHEMzMknJtY0fp/Cv/+94=Nanduri R. Prabhakar41.78927490000000-87.601250000000001680Prabhakar, Nanduri R.ProfessorTara O.HendersonTara O. Henderson41.78927490000000-87.60125000000000406Henderson, Tara O.ProfessorChristopherRhodesChristopher J. Rhodes41.78927490000000-87.60125000000000926Rhodes, ChristopherEmeritus/Emerita, Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1Emeritus/Emerita, ProfessorEmeritus/Emerita, Professortrue1ProfessorProfessortrue1ProfessorProfessor25722288Jansen LA, Mirzaa GM, Ishak GE, O'Roak BJ, Hiatt JB, Roden WH, Gunter SA, Christian SL, Collins S, Adams C, Rivière JB, St-Onge J, Ojemann JG, Shendure J, Hevner RF, Dobyns WBBrain : a journal of neurologyPI3K/AKT pathway mutations cause a spectrum of brain malformations from megalencephaly to focal cortical dysplasia. Brain. 2015 Jun; 138(Pt 6):1613-28.Brain2015-02-25T00:00:002015PI3K/AKT pathway mutations cause a spectrum of brain malformations from megalencephaly to focal cortical dysplasia.Medicine-Emergency MedicineMedicine-Endocrinology