D012330Chemicals & DrugsD13.444.735.490G02.111.570.820.486.775G05.360.580.77516220.988842RNA, Double-Strandedprns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonMolecular Genetics and Cell Biology28814792Kim-Hellmuth S, Bechheim M, Pütz B, Mohammadi P, Nédélec Y, Giangreco N, Becker J, Kaiser V, Fricker N, Beier E, Boor P, Castel SE, Nöthen MM, Barreiro LB, Pickrell JK, Müller-Myhsok B, Lappalainen T, Schumacher J, Hornung VNature communicationsGenetic regulatory effects modified by immune activation contribute to autoimmune disease associations. Nat Commun. 2017 08 16; 8(1):266.Nat Commun2017-08-16T00:00:002017Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations.30798990Khodarev NNInternational review of cell and molecular biologyIntracellular RNA Sensing in Mammalian Cells: Role in Stress Response and Cancer Therapies. Int Rev Cell Mol Biol. 2019; 344:31-89.Int Rev Cell Mol Biol2018-10-19T00:00:002018Intracellular RNA Sensing in Mammalian Cells: Role in Stress Response and Cancer Therapies.22912486Toroney R, Hull CM, Sokoloski JE, Bevilacqua PCRNA (New York, N.Y.)Mechanistic characterization of the 5'-triphosphate-dependent activation of PKR: lack of 5'-end nucleobase specificity, evidence for a distinct triphosphate binding site, and a critical role for the dsRBD. RNA. 2012 Oct; 18(10):1862-74.RNA2012-08-21T00:00:002012Mechanistic characterization of the 5'-triphosphate-dependent activation of PKR: lack of 5'-end nucleobase specificity, evidence for a distinct triphosphate binding site, and a critical role for the dsRBD.0.3884210.0087271116research area of0.8917020.016000131subject area for35922514Li Q, Gloudemans MJ, Geisinger JM, Fan B, Aguet F, Sun T, Ramaswami G, Li YI, Ma JB, Pritchard JK, Montgomery SB, Li JBNatureRNA editing underlies genetic risk of common inflammatory diseases. Nature. 2022 08; 608(7923):569-577.Nature2022-08-03T00:00:002022RNA editing underlies genetic risk of common inflammatory diseases.https://staley.uchicago.eduStaley Lab Websitehttp://www.hcleelab.orgLee Lab WebsiteHuman GeneticsNeurologyUniversity of ChicagoJonathan P.Staley3XF9Cq0QeczMknJtY0fp/Cv/+94=Jonathan P. Staley41.78927490000000-87.601250000000001221Staley, Jonathan P.ProfessorJonathanPritchardJonathan K. Pritchard41.78927490000000-87.601250000000001284Pritchard, JonathanPROFESSORGhanashyamGhadgeGhanashyam Ghadge41.78927490000000-87.601250000000002070Ghadge, GhanashyamSenior Research AssociateRalfKittlerRalf Kittler41.78927490000000-87.60125000000000695Kittler, Ralftrue1true1PROFESSORPROFESSORtrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Senior Research AssociateSenior Research AssociateHeng-ChiLeeHeng-Chi Lee0.000000000000000.000000000000003275Lee, Heng-ChiAssociate Professor21742363Rosebeck S, Sudini K, Chen T, Leaman DWVirologyInvolvement of Noxa in mediating cellular ER stress responses to lytic virus infection. Virology. 2011 Sep 01; 417(2):293-303.Virology2011-07-13T00:00:002011Involvement of Noxa in mediating cellular ER stress responses to lytic virus infection.