26396175Concepcion AR, Salas JT, Sáez E, Sarvide S, Ferrer A, Portu A, Uriarte I, Hervás-Stubbs S, Oude Elferink RP, Prieto J, Medina JFOncotargetAutoimmune Diseases; CD8-Positive T-Lymphocytes; Cholangitis; Liver; Lymphocyte Activation; Programmed Cell Death 1 ReceptorAge Factors; Animals; Apoptosis; B7-H1 Antigen; Cell Proliferation; Cells, Cultured; Chloride-Bicarbonate Antiporters; Clonal Deletion; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Female; Genetic Predisposition to Disease; Male; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Knockout; Phenotype; Signal Transduction; T-Lymphocytes, Regulatory; TransfectionCD8+ T cells undergo activation and programmed death-1 repression in the liver of aged Ae2a,b-/- mice favoring autoimmune cholangitis. Oncotarget. 2015 Oct 06; 6(30):28588-606.Oncotarget2015-10-06T00:00:002015CD8+ T cells undergo activation and programmed death-1 repression in the liver of aged Ae2a,b-/- mice favoring autoimmune cholangitis.plugins:TwitterTwitterprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:orcidIdORCID idPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD000367Concepts & Ideas62718420.694019Age FactorsD000818Living Beings1457265180.249624AnimalsD001327Disorders1332410.830421Autoimmune DiseasesBiochemistry and Molecular BiologyD002761Disorders16190.985285CholangitisD008807Living Beings26110470.820932Mice, Inbred BALB CD008099Anatomy34612290.672325LiverD005260Physiology1992444050.191167FemaleD008297Physiology1931408600.201617MaleD017637Physiology17230.987474Clonal DeletionD017209Physiology41016780.608637ApoptosisD018345Living Beings43819180.695188Mice, KnockoutD018414Anatomy1605560.744835CD8-Positive T-LymphocytesD049109Physiology43515710.639735Cell ProliferationD027963Chemicals & Drugs7110.992915Chloride-Bicarbonate AntiportersD060890Chemicals & Drugs952500.845929B7-H1 AntigenAxelConcepcionAxel Concepcion41.7886000000000087.598699999999994173Concepcion, Axel0000-0003-2971-3488Assistant ProfessorAuthorship 15556110.5556940.5556941authors10.2527has subject areaD057507Living Beings48550.981039Mice, 129 StrainD014162PhysiologyProcedures2878950.851303TransfectionD019175Physiology1976220.705339DNA MethylationD050378Anatomy1092950.798608T-Lymphocytes, RegulatoryD061026Chemicals & Drugs911590.882236Programmed Cell Death 1 ReceptorD002478Anatomy60328100.667881Cells, CulturedD004195Disorders59222270.601904Disease Models, AnimalD008213PhysiologyProcedures1877270.790101Lymphocyte ActivationD010641Physiology64723750.615854PhenotypeD015398Physiology69932330.460036Signal TransductionD020022Physiology39922670.521961Genetic Predisposition to DiseaseD044127Physiology2004760.725889Epigenesis, GeneticTwitter @AxelRConcepcio1https://concepcionlab.comThe Concepcion LabUniversity of Chicagotrue1Assistant ProfessorAssistant Professor