D056811PhenomenaG02.111.660.871.790.600.962G02.111.691.600.850G03.734.871.790.600.850G05.308.670.600.85020390.96269Unfolded Protein Responseprns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonMolecular Genetics and Cell BiologyDavidPincusx2tnCLQGOfnamXNnYUHhvWD+6g==David Pincus41.7886000000000087.598699999999993739Pincus, DavidAssistant ProfessorMedicine-Gastroenterology30352046Jo S, Fonseca TL, Bocco BMLC, Fernandes GW, McAninch EA, Bolin AP, Da Conceição RR, Werneck-de-Castro JP, Ignacio DL, Egri P, Németh D, Fekete C, Bernardi MM, Leitch VD, Mannan NS, Curry KF, Butterfield NC, Bassett JHD, Williams GR, Gereben B, Ribeiro MO, Bianco ACThe Journal of clinical investigationType 2 deiodinase polymorphism causes ER stress and hypothyroidism in the brain. J Clin Invest. 2019 01 02; 129(1):230-245.J Clin Invest2018-12-03T00:00:002018Type 2 deiodinase polymorphism causes ER stress and hypothyroidism in the brain.30923003Dzhashiashvili Y, Monckton CP, Shah HS, Kunjamma RB, Popko BNeurobiology of diseaseThe UPR-PERK pathway is not a promising therapeutic target for mutant SOD1-induced ALS. Neurobiol Dis. 2019 07; 127:527-544.Neurobiol Dis2019-03-26T00:00:002019The UPR-PERK pathway is not a promising therapeutic target for mutant SOD1-induced ALS.31031005Mogilenko DA, Haas JT, L'homme L, Fleury S, Quemener S, Levavasseur M, Becquart C, Wartelle J, Bogomolova A, Pineau L, Molendi-Coste O, Lancel S, Dehondt H, Gheeraert C, Melchior A, Dewas C, Nikitin A, Pic S, Rabhi N, Annicotte JS, Oyadomari S, Velasco-Hernandez T, Cammenga J, Foretz M, Viollet B, Vukovic M, Villacreces A, Kranc K, Carmeliet P, Marot G, Boulter A, Tavernier S, Berod L, Longhi MP, Paget C, Janssens S, Staumont-Sallé D, Aksoy E, Staels B, Dombrowicz DCellMetabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR. Cell. 2019 05 16; 177(5):1201-1216.e19.Cell2019-04-25T00:00:002019Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR.ScottOakesScott Oakes41.7886000000000087.598699999999993838Oakes, ScottProfessorRaghuMirmiraRaghu Mirmira41.7886000000000087.598699999999993890Mirmira, RaghuProfessor33177154Abderrahman B, Maximov PY, Curpan RF, Fanning SW, Hanspal JS, Fan P, Foulds CE, Chen Y, Malovannaya A, Jain A, Xiong R, Greene GL, Tonetti DA, Thatcher GRJ, Jordan VCMolecular cancer therapeuticsRapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer. Mol Cancer Ther. 2021 01; 20(1):11-25.Mol Cancer Ther2020-11-11T00:00:002020Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer.MaryRinellaMary Rinella41.7886000000000087.598699999999994118Rinella, MaryProfessor35405004Ibarra J, Elbanna YA, Kurylowicz K, Ciboddo M, Greenbaum HS, Arellano NS, Rodriguez D, Evers M, Bock-Hughes A, Liu C, Smith Q, Lutze J, Baumeister J, Kalmer M, Olschok K, Nicholson B, Silva D, Maxwell L, Dowgielewicz J, Rumi E, Pietra D, Casetti IC, Catricala S, Koschmieder S, Gurbuxani S, Schneider RK, Oakes SA, Elf SEBlood cancer discoveryType I but Not Type II Calreticulin Mutations Activate the IRE1a/XBP1 Pathway of the Unfolded Protein Response to Drive Myeloproliferative Neoplasms. Blood Cancer Discov. 2022 07 06; 3(4):298-315.Blood Cancer Discov2022-07-06T00:00:002022Type I but Not Type II Calreticulin Mutations Activate the IRE1a/XBP1 Pathway of the Unfolded Protein Response to Drive Myeloproliferative Neoplasms.2.383870.023110920research area of0.8871450.096026441subject area forhttp://pathology.uchicago.eduUChicago Dept of Pathologyhttp://www.oakeslab.uchicago.eduOakes Lab WebsiteNeurologyPathologyUniversity of Chicagohttps://pincuslab.uchicago.edu/Pincus LabRaymond P.RoosxXBmBLI1F+nMg3Vob0H3vWfp+4Wo6r1Xc3h9eaOOFmI=Raymond P. Roos41.78927490000000-87.601250000000001191Roos, Raymond P.Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessortrue1ProfessorProfessorMedicine-Endocrinology