D051820Chemicals & DrugsD12.776.260.730D12.776.660.235.400.800D12.776.664.235.400.800D12.776.930.87513230.988968TCF Transcription Factorsprns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonGokhan M.Mutlu0G98H611OfnamXNnYUHhvWD+6g==Gokhan M. Mutlu0.000000000000000.000000000000002890Mutlu, Gokhan M.Professor20348951Kwon IK, Wang R, Thangaraju M, Shuang H, Liu K, Dashwood R, Dulin N, Ganapathy V, Browning DDOncogenePKG inhibits TCF signaling in colon cancer cells by blocking beta-catenin expression and activating FOXO4. Oncogene. 2010 Jun 10; 29(23):3423-34.Oncogene2010-03-29T00:00:002010PKG inhibits TCF signaling in colon cancer cells by blocking beta-catenin expression and activating FOXO4.19934000Villareal DT, Robertson H, Bell GI, Patterson BW, Tran H, Wice B, Polonsky KSDiabetesTCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action. Diabetes. 2010 Feb; 59(2):479-85.Diabetes2009-11-23T00:00:002009TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action.20682688Freathy RM, Hayes MG, Urbanek M, Lowe LP, Lee H, Ackerman C, Frayling TM, Cox NJ, Dunger DB, Dyer AR, Hattersley AT, Metzger BE, Lowe WL, HAPO Study Cooperative Research GroupDiabetesHyperglycemia and Adverse Pregnancy Outcome (HAPO) study: common genetic variants in GCK and TCF7L2 are associated with fasting and postchallenge glucose levels in pregnancy and with the new consensus definition of gestational diabetes mellitus from the International Association of Diabetes and Pregnancy Study Groups. Diabetes. 2010 Oct; 59(10):2682-9.Diabetes2010-08-03T00:00:002010Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study: common genetic variants in GCK and TCF7L2 are associated with fasting and postchallenge glucose levels in pregnancy and with the new consensus definition of gestational diabetes mellitus from the International Association of Diabetes and Pregnancy Study Groups.0.4376760.011921713research area of0.3881360.032271522subject area for19933277Flozak AS, Lam AP, Russell S, Jain M, Peled ON, Sheppard KA, Beri R, Mutlu GM, Budinger GR, Gottardi CJThe Journal of biological chemistryBeta-catenin/T-cell factor signaling is activated during lung injury and promotes the survival and migration of alveolar epithelial cells. J Biol Chem. 2010 Jan 29; 285(5):3157-67.J Biol Chem2009-11-20T00:00:002009Beta-catenin/T-cell factor signaling is activated during lung injury and promotes the survival and migration of alveolar epithelial cells.https://mutlulab.uchicago.edu/Mutlu LabMedicinePathologyUniversity of ChicagoSusannahSpiessxHF5AqQGOeLWg25sc07h4WC08Nm6Susannah Spiess41.78927490000000-87.601250000000001012Spiess, SusannahKenneth S.PolonskyKenneth S. Polonsky41.78927490000000-87.601250000000002326Polonsky, Kenneth S.ProfessorBarbara LynneKeeBarbara Lynne Kee41.78927490000000-87.60125000000000308Kee, Barbara LynneProfessorYusukeNakamuraYusuke Nakamura41.78927490000000-87.60125000000000582Nakamura, YusukeEmeritus/Emerita, Professortrue1true1Emeritus/Emerita, ProfessorEmeritus/Emerita, Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessor16273202Takahashi M, Nakamura Y, Obama K, Furukawa YInternational journal of oncologyIdentification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer. Int J Oncol. 2005 Dec; 27(6):1483-7.Int J Oncol2005-12-01T00:00:002005Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer.Medicine-Endocrinology