D037761Chemicals & DrugsD08.811.277.087.520.200.650D08.811.913.400.725.115.961D12.776.476.90022450.960046Sirtuinsprns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson30407871Samant SA, Pillai VB, Gupta MPCanadian journal of physiology and pharmacologyCellular mechanisms promoting cachexia and how they are opposed by sirtuins 1. Can J Physiol Pharmacol. 2019 Apr; 97(4):235-245.Can J Physiol Pharmacol2019-04-01T00:00:002019Cellular mechanisms promoting cachexia and how they are opposed by sirtuins 1.28928419Samant SA, Kanwal A, Pillai VB, Bao R, Gupta MPScientific reportsThe histone deacetylase SIRT6 blocks myostatin expression and development of muscle atrophy. Sci Rep. 2017 09 19; 7(1):11877.Sci Rep2017-09-19T00:00:002017The histone deacetylase SIRT6 blocks myostatin expression and development of muscle atrophy.31318577Kanwal A, Pillai VB, Samant S, Gupta M, Gupta MPFASEB journal : official publication of the Federation of American Societies for Experimental BiologyThe nuclear and mitochondrial sirtuins, Sirt6 and Sirt3, regulate each other's activity and protect the heart from developing obesity-mediated diabetic cardiomyopathy. FASEB J. 2019 10; 33(10):10872-10888.FASEB J2019-07-12T00:00:002019The nuclear and mitochondrial sirtuins, Sirt6 and Sirt3, regulate each other's activity and protect the heart from developing obesity-mediated diabetic cardiomyopathy.33308014Pillai VB, Gupta MPAmerican journal of physiology. Endocrinology and metabolismIs nuclear sirtuin SIRT6 a master regulator of immune function? Am J Physiol Endocrinol Metab. 2021 03 01; 320(3):E399-E414.Am J Physiol Endocrinol Metab2020-12-14T00:00:002020Is nuclear sirtuin SIRT6 a master regulator of immune function?Ben May Department of Cancer Research33934090Pillai VB, Samant S, Hund S, Gupta M, Gupta MPAgingThe nuclear sirtuin SIRT6 protects the heart from developing aging-associated myocyte senescence and cardiac hypertrophy. Aging (Albany NY). 2021 05 02; 13(9):12334-12358.Aging (Albany NY)2021-05-02T00:00:002021The nuclear sirtuin SIRT6 protects the heart from developing aging-associated myocyte senescence and cardiac hypertrophy.4.708090.017308322research area of0.8176270.040111632subject area forhttp://maheshguptalaboratory.weebly.comMahesh Gupta Laboratoryhttp://medicine.uchicago.edu/sections/dermatology/research-programs/He Grouphttps://he-lab.uchicago.eduHe LabHuman GeneticsUniversity of ChicagoMahesh P.GuptaMahesh P. Gupta41.78927490000000-87.601250000000002244Gupta, Mahesh P.ProfessorYu-YingHeznthDoF1GuTQkntjbwjr93A=Yu-Ying He41.78927490000000-87.60125000000000496He, Yu-YingProfessorZiaKhanZia Khan41.78927490000000-87.60125000000000497Khan, ZiaPostdoctoral FellowYingmingZhaoYingming Zhao41.78927490000000-87.6012500000000073Zhao, YingmingProfessorGene H.KimGene H. Kim41.78927490000000-87.60125000000000921Kim, Gene H.Associate Professortrue1ProfessorProfessortrue1Postdoctoral FellowPostdoctoral Fellowtrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1ProfessorProfessorMedicine-CardiologySurgery-CardiacMedicine-Dermatology