D051716Chemicals & DrugsD12.776.260.7009160.990043Replication Protein Aplugins:FeaturedVideosFeatured Videosprns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:orcidIdORCID idPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson20957187Lee HC, Aalto AP, Yang Q, Chang SS, Huang G, Fisher D, Cha J, Poranen MM, Bamford DH, Liu YPLoS biologyThe DNA/RNA-dependent RNA polymerase QDE-1 generates aberrant RNA and dsRNA for RNAi in a process requiring replication protein A and a DNA helicase. PLoS Biol. 2010 Oct 05; 8(10).PLoS Biol2010-10-05T00:00:002010The DNA/RNA-dependent RNA polymerase QDE-1 generates aberrant RNA and dsRNA for RNAi in a process requiring replication protein A and a DNA helicase.Molecular Genetics and Cell BiologyRadiation and Cellular OncologyMedicine-Genetic Medicine30462332Chan YL, Zhang A, Weissman BP, Bishop DKNucleic acids researchRPA resolves conflicting activities of accessory proteins during reconstitution of Dmc1-mediated meiotic recombination. Nucleic Acids Res. 2019 01 25; 47(2):747-761.Nucleic Acids Res2019-01-25T00:00:002019RPA resolves conflicting activities of accessory proteins during reconstitution of Dmc1-mediated meiotic recombination.30309964Liu P, Rojo de la Vega M, Sammani S, Mascarenhas JB, Kerins M, Dodson M, Sun X, Wang T, Ooi A, Garcia JGN, Zhang DDProceedings of the National Academy of Sciences of the United States of AmericaRPA1 binding to NRF2 switches ARE-dependent transcriptional activation to ARE-NRE-dependent repression. Proc Natl Acad Sci U S A. 2018 10 30; 115(44):E10352-E10361.Proc Natl Acad Sci U S A2018-10-11T00:00:002018RPA1 binding to NRF2 switches ARE-dependent transcriptional activation to ARE-NRE-dependent repression.25787788Chen J, Le S, Basu A, Chazin WJ, Yan JScientific reportsMechanochemical regulations of RPA's binding to ssDNA. Sci Rep. 2015 Mar 19; 5:9296.Sci Rep2015-03-19T00:00:002015Mechanochemical regulations of RPA's binding to ssDNA.1.061750.01922039research area of0.6986040.042084513subject area forhttp://bishoplab.bsd.uchicago.edu/Bishop Lab Websitehttps://biologicalsciences.uchicago.edu/faculty/stephen-j-kron-md-phdFaculty Profilehttps://mgcb.uchicago.edu/Department of Molecular Genetics & Cell Biologyhttp://www.hcleelab.orgLee Lab Websitehttp://wordpress.uchospitals.edu/basu-lab/Basu Labhttps://voices.uchicago.edu/kronlab/Kron LabUniversity of ChicagoDouglas K.Bishop02BgGKkaCczbgn4qdUXm+mb7+MTz7LFLDouglas K. Bishop41.78927490000000-87.601250000000002358Bishop, Douglas K.ProfessorJosephMascarenhasJoseph Mascarenhas41.78927490000000-87.601250000000002655Mascarenhas, JosephStephen J.KronxGl7BK81DO/RmHllZ0mg9mHvStephen J. Kron41.78927490000000-87.60125000000000665Kron, Stephen J.Professortrue1true1Assistant ProfessorAssistant Professortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1ProfessorProfessor26019182Tsabar M, Eapen VV, Mason JM, Memisoglu G, Waterman DP, Long MJ, Bishop DK, Haber JENucleic acids researchCaffeine impairs resection during DNA break repair by reducing the levels of nucleases Sae2 and Dna2. Nucleic Acids Res. 2015 Aug 18; 43(14):6889-901.Nucleic Acids Res2015-05-27T00:00:002015Caffeine impairs resection during DNA break repair by reducing the levels of nucleases Sae2 and Dna2.Heng-ChiLeeHeng-Chi Lee0.000000000000000.000000000000003275Lee, Heng-ChiAssociate ProfessorAninditaBasuAnindita Basu0.000000000000000.000000000000003403Basu, Anindita0000-0001-9468-3727Assistant Professor