D002243Chemicals & DrugsD03.383.725.150D03.633.100.473.155D03.633.300.154680.99151CarbolinesFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:orcidIdORCID idPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonComparative Human DevelopmentDarioMaestripieriDario Maestripieri41.7886000000000087.598699999999993479Maestripieri, DarioProfessorMedicine-Hematology and Oncology35362793Papachristos A, Ratain MJCancer chemotherapy and pharmacologyLurbinectedin-induced thrombocytopenia: the role of body surface area. Cancer Chemother Pharmacol. 2022 05; 89(5):573-575.Cancer Chemother Pharmacol2022-04-01T00:00:002022Lurbinectedin-induced thrombocytopenia: the role of body surface area.0.9414670.08520676research area of0.6076510.06588589subject area forNeurologySurgeryUniversity of ChicagoEmilyRogalskiEmily Rogalski41.7886000000000087.598699999999994397Rogalski, Emily0000-0002-6472-1363Professor35945628Martersteck A, Ayala I, Ohm DT, Spencer C, Coventry C, Weintraub S, Bigio EH, Mesulam M-, Geula C, Rogalski EActa neuropathologica communicationsFocal amyloid and asymmetric tau in an imaging-to-autopsy case of clinical primary progressive aphasia with Alzheimer disease neuropathology. Acta Neuropathol Commun. 2022 08 09; 10(1):111.Acta Neuropathol Commun2022-08-09T00:00:002022Focal amyloid and asymmetric tau in an imaging-to-autopsy case of clinical primary progressive aphasia with Alzheimer disease neuropathology.Mark J.RatainMark J. Ratain41.78927490000000-87.601250000000001401Ratain, Mark J.ProfessorAdamMartersteckAdam Martersteck41.7886000000000087.598699999999994454Martersteck, AdamAssistant Professorhttps://voices.uchicago.edu/haarc/Healthy Aging & Alzheimer's Research Care Centertrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessor24563480Elez ME, Tabernero J, Geary D, Macarulla T, Kang SP, Kahatt C, Pita AS, Teruel CF, Siguero M, Cullell-Young M, Szyldergemajn S, Ratain MJClinical cancer research : an official journal of the American Association for Cancer ResearchFirst-in-human phase I study of Lurbinectedin (PM01183) in patients with advanced solid tumors. Clin Cancer Res. 2014 Apr 15; 20(8):2205-14.Clin Cancer Res2014-02-21T00:00:002014First-in-human phase I study of Lurbinectedin (PM01183) in patients with advanced solid tumors.1010NishantAgrawalNishant Agrawal0.000000000000000.000000000000003264Agrawal, NishantProfessor25564570Califano JA, Khan Z, Noonan KA, Rudraraju L, Zhang Z, Wang H, Goodman S, Gourin CG, Ha PK, Fakhry C, Saunders J, Levine M, Tang M, Neuner G, Richmon JD, Blanco R, Agrawal N, Koch WM, Marur S, Weed DT, Serafini P, Borrello IClinical cancer research : an official journal of the American Association for Cancer ResearchTadalafil augments tumor specific immunity in patients with head and neck squamous cell carcinoma. Clin Cancer Res. 2015 Jan 01; 21(1):30-8.Clin Cancer Res2015-01-01T00:00:002015Tadalafil augments tumor specific immunity in patients with head and neck squamous cell carcinoma.28105566Jimeno A, Sharma MR, Szyldergemajn S, Gore L, Geary D, Diamond JR, Fernandez Teruel C, Soto Matos-Pita A, Iglesias JL, Cullell-Young M, Ratain MJInvestigational new drugsPhase I study of lurbinectedin, a synthetic tetrahydroisoquinoline that inhibits activated transcription, induces DNA single- and double-strand breaks, on a weekly × 2 every-3-week schedule. Invest New Drugs. 2017 08; 35(4):471-477.Invest New Drugs2017-01-20T00:00:002017Phase I study of lurbinectedin, a synthetic tetrahydroisoquinoline that inhibits activated transcription, induces DNA single- and double-strand breaks, on a weekly × 2 every-3-week schedule.