D003170PhysiologyG12.274.69510130.994652Complement Pathway, Alternativeplugins:TwitterTwitterprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation ResourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson31545648Frid MG, McKeon BA, Thurman JM, Maron BA, Li M, Zhang H, Kumar S, Sullivan T, Laskowsky J, Fini MA, Hu S, Tuder RM, Gandjeva A, Wilkins MR, Rhodes CJ, Ghataorhe P, Leopold JA, Wang RS, Holers VM, Stenmark KRAmerican journal of respiratory and critical care medicineImmunoglobulin-driven Complement Activation Regulates Proinflammatory Remodeling in Pulmonary Hypertension. Am J Respir Crit Care Med. 2020 01 15; 201(2):224-239.Am J Respir Crit Care Med2020-01-15T00:00:002020Immunoglobulin-driven Complement Activation Regulates Proinflammatory Remodeling in Pulmonary Hypertension.32540405Zhang Y, Kremsdorf RA, Sperati CJ, Henriksen KJ, Mori M, Goodfellow RX, Pitcher GR, Benson CL, Borsa NG, Taylor RP, Nester CM, Smith RJHKidney internationalMutation of complement factor B causing massive fluid-phase dysregulation of the alternative complement pathway can result in atypical hemolytic uremic syndrome. Kidney Int. 2020 11; 98(5):1265-1274.Kidney Int2020-06-12T00:00:002020Mutation of complement factor B causing massive fluid-phase dysregulation of the alternative complement pathway can result in atypical hemolytic uremic syndrome.Radiology-Neuroradiology17523212Alexander JJ, Jacob A, Vezina P, Sekine H, Gilkeson GS, Quigg RJEuropean journal of immunologyAbsence of functional alternative complement pathway alleviates lupus cerebritis. Eur J Immunol. 2007 Jun; 37(6):1691-701.Eur J Immunol2007-06-01T00:00:002007Absence of functional alternative complement pathway alleviates lupus cerebritis.34139209Mahajan S, Jacob A, Kelkar A, Chang A, Mcskimming D, Neelamegham S, Quigg RJ, Alexander JJKidney internationalLocal complement factor H protects kidney endothelial cell structure and function. Kidney Int. 2021 10; 100(4):824-836.Kidney Int2021-06-15T00:00:002021Local complement factor H protects kidney endothelial cell structure and function.22492944Thurman JM, Tchepeleva SN, Haas M, Panzer S, Boackle SA, Glogowska MJ, Quigg RJ, Holers VMAmerican journal of physiology. Renal physiologyComplement alternative pathway activation in the autologous phase of nephrotoxic serum nephritis. Am J Physiol Renal Physiol. 2012 Jun 15; 302(12):F1529-36.Am J Physiol Renal Physiol2012-04-04T00:00:002012Complement alternative pathway activation in the autologous phase of nephrotoxic serum nephritis.ElaineTanhehcoElaine Tanhehco41.7886000000000087.598699999999994199Tanhehco, ElaineAssistant Professor0.489140.024787810research area of0.4358540.043472610subject area forChangUCanSpareMedicinePathologyPediatricsUniversity of ChicagoPaulVezinaPaul Vezina41.78927490000000-87.601250000000001492Vezina, PaulPROFESSORAnthonyChangAnthony Chang41.78927490000000-87.601250000000002601Chang, AnthonyProfessorRichardQuiggRichard Quigg41.78927490000000-87.60125000000000527Quigg, RichardEmeritus/Emerita, ProfessorChristopher W.ClardyChristopher W. Clardy41.78927490000000-87.60125000000000857Clardy, Christopher W.Associate Professortrue1Emeritus/Emerita, ProfessorEmeritus/Emerita, Professortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1PROFESSORPROFESSORtrue1Assistant ProfessorAssistant ProfessorPsychiatry & Behav. Neurosci